4.6 Article

Superhydrophobic silver film as a SERS substrate for the detection of uric acid and creatinine

Journal

BIOMEDICAL OPTICS EXPRESS
Volume 9, Issue 10, Pages 4988-4997

Publisher

OPTICAL SOC AMER
DOI: 10.1364/BOE.9.004988

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Funding

  1. National Natural Science Foundation of China [61575043]
  2. Natural Science Foundation of Fujian Province of China [2016J01292]
  3. Program for New Century Excellent Talent in Fujian Province [J1-1160]

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Superhydrophobic silver films were fabricated by silver-mirror reaction and surface functionalization with thiol. The thiol-functionalization significantly improved the hydrophobic property of the Ag films (AFS), and their contact angle values slightly increased with the extension of a thiol alkyl chain, reaching about 160 degrees. The surface-enhanced Raman scattering (SERS) detection capacity of these films were investigated, and AFS-Dodcc showed the best substrate for R6G molecule detection with the concentration limit of 10(-11) M. AFS functionalized with dodecanethiol (AFS-Dodec) was applied for the SERS detection of uric acid and creatinine, it exhibited good linear dependence relationship between the Raman intensity and analyte concentration in the concentration range of 5 similar to 1000 mu M. (C) 2018 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

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