Review
Health Care Sciences & Services
Guilian Chen, Tong Wang, Lirong Zhong, Xinghui He, Chunxia Huang, Yingmin Wang, Kun Li
Summary: Telemedicine is a feasible way to prevent pressure injuries among patients with spinal cord injuries. It can decrease the incidence and severity of pressure injuries and accelerate patients' healing without imposing an economic burden. It is best used in tandem with other, more conventional interventions.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Review
Clinical Neurology
Mathias Moller Thygesen, Tim Damgaard Nielsen, Mads Rasmussen, Dariusz Orlowski, Michael Pedersen, Mikkel Mylius Rasmussen
Summary: Interventions on spinal cord perfusion pressure may have a positive correlation with neurological outcome in traumatic spinal cord injuries, but causality cannot be confirmed due to limited literature. Further well-designed studies are needed to address this issue.
EUROPEAN SPINE JOURNAL
(2021)
Review
Clinical Neurology
Carly Weber-Levine, Brendan F. Judy, Andrew M. Hersh, Tolulope Awosika, Yohannes Tsehay, Timothy Kim, Alejandro Chara, Nicholas Theodore
Summary: This study reviewed the current evidence supporting SCPP as a stronger predictor of outcomes in traumatic spinal cord injury, while also indicating inconclusive evidence on the effectiveness of CSF drainage for reducing ISP.
JOURNAL OF NEUROSURGERY-SPINE
(2022)
Article
Health Care Sciences & Services
Nicole M. Vecin, David R. Gater
Summary: This manuscript reviews the risk of pressure injuries caused by spinal cord injury and discusses the multidisciplinary approach required to prevent and treat these injuries in the vulnerable population.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Article
Surgery
Sarah Rose Adamson, Sarah Whitty, Stephen Flood, Derek Neoh, Andrew Nunn, Ben Clegg, Sally Kiu-Huen Ng
Summary: This retrospective data analysis investigates the factors contributing to pressure ulcers (PU) in spinal cord injury (SCI) patients, reviews the current management protocol, and assesses the risk of recurrence. The study found that among the 93 patients analyzed, there were 195 surgeries for 129 PUs, with the majority classified as grade 3 or 4 and 53% having osteomyelitis. Debridement alone was the most common surgical management, followed by flap reconstruction. Post-operative complications were observed in 41% of surgeries, with infection being the most prominent. 11% of PUs recurred at least 4 months after initial presentation.
ANZ JOURNAL OF SURGERY
(2023)
Article
Clinical Neurology
Perry Dhaliwal, Alwyn Gomez, Frederick Adam Zeiler
Summary: Acute traumatic spinal cord injury is commonly treated with surgical decompression and instrumentation of the spine. However, the evidence for these methods is limited. There is now interest in measuring spinal cord perfusion pressure through monitoring mean arterial pressure and intraspinal pressure. This study successfully used a strain gauge pressure transducer to measure intraspinal pressure and derive spinal cord perfusion pressure.
FRONTIERS IN NEUROLOGY
(2023)
Article
Nursing
Elizabeth Burkhart, Stacey Zurek, Mary E. Desmond, Keith Aguina, Ralph D. Cabigon, Autumn Smith, Barbara Bates-Jensen
Summary: This study aimed to develop and pilot an educational curriculum for healthcare providers to better understand community-acquired pressure injury (CAPrI) prevention. The Thomas six-step process model guided the development and evaluation of the curriculum. A five-module online curriculum was positively evaluated and is publicly available.
REHABILITATION NURSING
(2023)
Article
Dermatology
Angela Grigatti, Amit Gefen
Summary: The study found that using dressing cuts can reduce the pressure on facial tissues from continuous positive airway pressure masks, minimizing the risk of injuries, with the best performance seen at the nasal bridge and cheeks.
INTERNATIONAL WOUND JOURNAL
(2022)
Review
Nutrition & Dietetics
Jonas Campos, Nuno A. Silva, Antonio J. Salgado
Summary: Spinal cord injury is a condition that leads to motor, sensory, and autonomic impairments, and nutritional interventions have been proposed as a way to circumvent these issues. Published data have shown that nutritional interventions can improve various relevant pathophysiological processes of SCI, ultimately leading to neuroprotection and neuroplasticity.
Article
Nursing
Tarja Tervo-Heikkinen, Anniina Heikkila, Marita Koivunen, Tiina Kortteisto, Jaana Peltokoski, Susanne Salmela, Merja Sankelo, Tuija Ylitormanen, Kristiina Junttila
Summary: This study explores the prevention of pressure injuries in Finnish acute inpatient care. The results show that risk assessments and preventive interventions for pressure injuries are irregularly conducted, highlighting the gaps in evidence-based nursing practice.
Review
Chemistry, Multidisciplinary
He Shen, Caixia Fan, Zhifeng You, Zhifeng Xiao, Yannan Zhao, Jianwu Dai
Summary: Spinal cord injury (SCI) leads to the loss of motor and sensory functions and understanding the pathophysiological changes and inhibitory microenvironment is crucial for potential mechanisms of functional restoration. Implantation of functionalized biomaterials and transplantation of spinal cord tissue grafts have shown promising results for SCI repair, opening up new avenues for treatment.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Clinical Neurology
Lisa Burkhart, Lisa Skemp, Sameer Siddiqui
Summary: This study explored risks, resources, and actions associated with preventing community acquired pressure injuries (CAPrI) from the perspective of veterans living with spinal cord injury (SCI) in the community. Results revealed a model describing veterans' perspective of preventing CAPrIs associated with SCI, including three themes and nine subthemes, providing important insights for improving veteran quality of life.
JOURNAL OF SPINAL CORD MEDICINE
(2021)
Article
Critical Care Medicine
Ravindran Visagan, Florence R. A. Hogg, Mathew J. Gallagher, Siobhan Kearney, Argyro Zoumprouli, Marios C. Papadopoulos, Samira Saadoun
Summary: This study examines the feasibility of monitoring tissue oxygen tension in patients with acute, severe traumatic spinal cord injuries. The results show that tissue oxygen tension is influenced by various factors, including intraspinal pressure, spinal cord perfusion pressure, tissue glucose levels, lactate/pyruvate ratio, and fever. In patients with motor-incomplete injuries, fluctuations in tissue oxygen tension correlate with fluctuations in limb motor score.
CRITICAL CARE MEDICINE
(2022)
Article
Rehabilitation
Daniela Mitiyo Odagiri Utiyama, Fabio Marcon Alfieri, Vinicius Delgado Ramos, Linamara Rizzo Battistella
Summary: This study surveyed individuals with spinal cord injury in south-eastern Brazil. The majority of participants were male and paraplegic, and spasticity and neuropathic pain were the most frequently reported health conditions. Despite reporting a good quality of life, they still encountered disabling environmental barriers and only a small proportion were able to return to work.
JOURNAL OF REHABILITATION MEDICINE
(2022)
Review
Cell Biology
Jing Chen, Norbert Weidner, Radhika Puttagunta
Summary: Physical activity-based rehabilitative interventions are important in treating neuropathic pain caused by spinal cord injury (SCI). Animal models have shown that these interventions can modulate inflammatory-related changes and induce structural and functional changes in the spinal cord circuitry. However, the cellular and molecular mechanisms behind this beneficial effect are not yet fully understood and further research is needed to develop individualized rehabilitative therapies.