The small-molecule BGP-15 protects against heart failure and atrial fibrillation in mice

Gαi2- and Gαi3-Deficient Mice Display Opposite Severity of Myocardial Ischemia Reperfusion Injury

(2014) David Köhler et al.   PLoS One

New insights into IGF-1 signaling in the heart

(2014) Rodrigo Troncoso et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

On ceramides, other sphingolipids and impaired glucose homeostasis

(2014) Philip J. Larsen et al.   Molecular Metabolism

Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling

(2013) Hannah J. Whittington et al.   CARDIOVASCULAR RESEARCH

Risk of atrial fibrillation as a function of the electrocardiographic PR interval: Results from the Copenhagen ECG Study

(2013) Jonas Bille Nielsen et al.   HEART RHYTHM

Plasma lipid profiling in a large population-based cohort

(2013) Jacquelyn M. Weir et al.   JOURNAL OF LIPID RESEARCH

Treatment of the Heart Failure Patient With Atrial Fibrillation

(2013) Michael R. Bristow et al.   JACC-Heart Failure

Beta-Blockers and Outcome in Heart Failure and Atrial Fibrillation

(2013) Michiel Rienstra et al.   JACC-Heart Failure

Heart Failure

(2013) Eugene Braunwald   JACC-Heart Failure

The HSP co-inducer BGP-15 can prevent the metabolic side effects of the atypical antipsychotics

(2012) Zsuzsanna Literáti-Nagy et al.   CELL STRESS & CHAPERONES

An Update on the Prognosis of Patients With Atrial Fibrillation

(2012) David D. McManus et al.   CIRCULATION

Heart Disease and Stroke Statistics—2013 Update

(2012) Alan S. Go et al.   CIRCULATION

Electrocardiographic PR Interval and Adverse Outcomes in Older Adults

(2012) Jared W. Magnani et al.   Circulation-Arrhythmia and Electrophysiology

Phosphoinositide 3-Kinase p110α Is a Master Regulator of Exercise-Induced Cardioprotection and PI3K Gene Therapy Rescues Cardiac Dysfunction

(2012) Kate L. Weeks et al.   Circulation-Heart Failure

Hydroximic Acid Derivatives: Pleiotropic Hsp Co-Inducers Restoring Homeostasis and Robustness

(2012) Tim Crul et al.   CURRENT PHARMACEUTICAL DESIGN

Overexpression of Sphingosine Kinase 1 Prevents Ceramide Accumulation and Ameliorates Muscle Insulin Resistance in High-Fat Diet-Fed Mice

(2012) C. R. Bruce et al.   DIABETES

BGP-15, a PARP-inhibitor, prevents imatinib-induced cardiotoxicity by activating Akt and suppressing JNK and p38 MAP kinases

(2012) Zsolt Sarszegi et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

(2012) Stefan M. Gehrig et al.   NATURE

Meta-analysis identifies six new susceptibility loci for atrial fibrillation

(2012) Patrick T Ellinor et al.   NATURE GENETICS

Connexins and Atrial Fibrillation

(2011) Takeshi Kato et al.   CIRCULATION

Molecular Genetic and Functional Characterization Implicate Muscle-Restricted Coiled-Coil Gene ( MURC ) as a Causal Gene for Familial Dilated Cardiomyopathy

(2011) Gabriela Rodriguez et al.   Circulation-Cardiovascular Genetics

Recent advances in the molecular pathophysiology of atrial fibrillation

(2011) Reza Wakili et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation

(2011) Deli Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation

(2011) Valentin Fuster et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Membrane-Lipid Therapy in Operation: The HSP Co-Inducer BGP-15 Activates Stress Signal Transduction Pathways by Remodeling Plasma Membrane Rafts

(2011) Imre Gombos et al.   PLoS One

Beneficial effect of the insulin sensitizer (HSP inducer) BGP-15 on olanzapine-induced metabolic disorders

(2010) B. Literáti-Nagy et al.   BRAIN RESEARCH BULLETIN

Atrial Fibrillation in Congestive Heart Failure

(2010) Steven A. Lubitz et al.   Heart Failure Clinics

Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation

(2009) Lynette Pretorius et al.   AMERICAN JOURNAL OF PATHOLOGY

Ganglioside GM3 and its biological functions

(2009) N. V. Prokazova et al.   BIOCHEMISTRY-MOSCOW

Improvement of Insulin Sensitivity by a Novel Drug, BGP-15, in Insulin-resistant Patients: A Proof of Concept Randomized Double-blind Clinical Trial

(2009) B. Literáti-Nagy et al.   HORMONE AND METABOLIC RESEARCH

Long-term Outcomes in Individuals With Prolonged PR Interval or First-Degree Atrioventricular Block

(2009) Susan Cheng   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Targeted Inhibition of Cardiomyocyte Gi Signaling Enhances Susceptibility to Apoptotic Cell Death in Response to Ischemic Stress

(2008) Brent R. DeGeorge et al.   CIRCULATION

ROLE OF INSULIN-LIKE GROWTH FACTOR 1 AND PHOSPHOINOSITIDE 3-KINASE IN A SETTING OF HEART DISEASE

(2008) Julie R McMullen   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

MURC, a Muscle-Restricted Coiled-Coil Protein That Modulates the Rho/ROCK Pathway, Induces Cardiac Dysfunction and Conduction Disturbance

(2008) T. Ogata et al.   MOLECULAR AND CELLULAR BIOLOGY

HSP72 protects against obesity-induced insulin resistance

(2008) J. Chung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Association of Met439Thr Substitution in Heat Shock Protein 70 Gene with Postoperative Atrial Fibrillation and Serum HSP70 Protein Levels

(2007) Ali R. Afzal et al.   CARDIOLOGY