Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis

Inhibition of Lymphangiogenesis and Angiogenesis in Breast Tumor Xenografts and Lymph Nodes by a Peptide Derived from Transmembrane Protein 45A

(2015) Esak Lee et al.   NEOPLASIA

The IL-6/JAK/Stat3 Feed-Forward Loop Drives Tumorigenesis and Metastasis

(2015) Qing Chang et al.   NEOPLASIA

Critical Role of STAT3 in IL-6–Mediated Drug Resistance in Human Neuroblastoma

(2013) Tasnim Ara et al.   CANCER RESEARCH

Pre-treatment of mice with tumor-conditioned media accelerates metastasis to lymph nodes and lungs: a new spontaneous breast cancer metastasis model

(2013) Esak Lee et al.   CLINICAL & EXPERIMENTAL METASTASIS

Epithelial to Mesenchymal Transition Promotes Breast Cancer Progression via a Fibronectin-dependent STAT3 Signaling Pathway

(2013) Nikolas Balanis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stat3-Targeted Therapies Overcome the Acquired Resistance to Vemurafenib in Melanomas

(2013) Fang Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Stat3-coordinated Lin-28–let-7–HMGA2 and miR-200–ZEB1 circuits initiate and maintain oncostatin M-driven epithelial–mesenchymal transition

(2013) L Guo et al.   ONCOGENE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

STAT3-RANTES Autocrine Signaling Is Essential for Tamoxifen Resistance in Human Breast Cancer Cells

(2012) E. H. Yi et al.   MOLECULAR CANCER RESEARCH

Role of STAT3 in Transformation and Drug Resistance in CML

(2012) Rajesh R. Nair et al.   Frontiers in Oncology

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Cross-Talk between Tumor Cells and the Microenvironment at the Metastatic Niche

(2011) M. J. Carlini et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Small peptides derived from somatotropin domain-containing proteins inhibit blood and lymphatic endothelial cell proliferation, migration, adhesion and tube formation

(2011) Esak Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition

(2011) Hua Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Endothelial FAK as a therapeutic target in disease

(2011) Giovanni A. Infusino et al.   MICROVASCULAR RESEARCH

The lymphatic vasculature in disease

(2011) Kari Alitalo   NATURE MEDICINE

Lymphangiogenesis: Molecular Mechanisms and Future Promise

(2010) Tuomas Tammela et al.   CELL

Stat3-dependent acute Rantes production in vascular smooth muscle cells modulates inflammation following arterial injury in mice

(2010) Jason C. Kovacic et al.   JOURNAL OF CLINICAL INVESTIGATION

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Ethanol Augments RANTES/CCL5 Expression in Rat Liver Sinusoidal Endothelial Cells and Human Endothelial Cells via Activation of NF- B, HIF-1 , and AP-1

(2009) S. M. Yeligar et al.   JOURNAL OF IMMUNOLOGY