The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The pyrido[b]indole MDM2 inhibitor SP-141 exerts potent therapeutic effects in breast cancer models
Authors
Keywords
-
Journal
Nature Communications
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2014-10-01
DOI
10.1038/ncomms6086
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2014
- (2014) Rebecca Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Small-molecule SMAC mimetics as new cancer therapeutics
- (2014) Longchuan Bai et al. PHARMACOLOGY & THERAPEUTICS
- The benefits and harms of breast cancer screening: an independent review
- (2013) M G Marmot et al. BRITISH JOURNAL OF CANCER
- Breast cancer statistics, 2013
- (2013) Carol DeSantis et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Targeting triple negative breast cancer: Is p53 the answer?
- (2013) Natalie Turner et al. CANCER TREATMENT REVIEWS
- Recent Advances in Validating MDM2 as a Cancer Target
- (2012) Elizabeth Rayburn et al. Anti-Cancer Agents in Medicinal Chemistry
- Molecular Pathways: Targeting Mdm2 and Mdm4 in Cancer Therapy
- (2012) Q. Li et al. CLINICAL CANCER RESEARCH
- Natural Product MDM2 Inhibitors: Anticancer Activity and Mechanisms of Action
- (2012) J.-J. Qin et al. CURRENT MEDICINAL CHEMISTRY
- Transcription Factor NFAT1 Activates themdm2Oncogene Independent of p53
- (2012) Xu Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of ribosomal protein S25 (RPS25)–MDM2–p53 regulatory feedback loop
- (2012) X Zhang et al. ONCOGENE
- Natural Product Ginsenoside 25-OCH3-PPD Inhibits Breast Cancer Growth and Metastasis through Down-Regulating MDM2
- (2012) Wei Wang et al. PLoS One
- New insights into the mechanisms of organ-specific breast cancer metastasis
- (2012) Girieca Lorusso et al. SEMINARS IN CANCER BIOLOGY
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Antagonists Induce a Conformational Change in cIAP1 That Promotes Autoubiquitination
- (2011) E. C. Dueber et al. SCIENCE
- Breast cancer assessment tools and optimizing adjuvant therapy
- (2010) Catherine Oakman et al. Nature Reviews Clinical Oncology
- Triple-negative breast cancer: disease entity or title of convenience?
- (2010) Lisa Carey et al. Nature Reviews Clinical Oncology
- Triple-Negative Breast Cancer
- (2010) William D. Foulkes et al. NEW ENGLAND JOURNAL OF MEDICINE
- A novel synthetic iminoquinone, BA-TPQ, as an anti-breast cancer agent: in vitro and in vivo activity and mechanisms of action
- (2009) Wei Wang et al. BREAST CANCER RESEARCH AND TREATMENT
- Regulation of XIAP Translation and Induction by MDM2 following Irradiation
- (2009) Lubing Gu et al. CANCER CELL
- In vitro and In vivo Anticancer Activity of Novel Synthetic Makaluvamine Analogues
- (2009) W. Wang et al. CLINICAL CANCER RESEARCH
- MDM2 Acts Downstream of p53 as an E3 Ligase to Promote FOXO Ubiquitination and Degradation
- (2009) Wei Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Murine double minute 2: p53-independent roads lead to genome instability or death
- (2009) Alyssa Bouska et al. TRENDS IN BIOCHEMICAL SCIENCES
- Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy
- (2008) Sanjeev Shangary et al. Annual Review of Pharmacology and Toxicology
- Targeting the MDM2-p53 Interaction for Cancer Therapy
- (2008) S. Shangary et al. CLINICAL CANCER RESEARCH
- Temporal activation of p53 by a specific MDM2 inhibitor is selectively toxic to tumors and leads to complete tumor growth inhibition
- (2008) S. Shangary et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now