Engineering light-inducible nuclear localization signals for precise spatiotemporal control of protein dynamics in living cells

A light-inducible organelle-targeting system for dynamically activating and inactivating signaling in budding yeast

(2013) Xiaojing Yang et al.   MOLECULAR BIOLOGY OF THE CELL

Nitrosative/Oxidative Stress Conditions Regulate Thioredoxin-Interacting Protein (TXNIP) Expression and Thioredoxin-1 (TRX-1) Nuclear Localization

(2013) Fernando Toshio Ogata et al.   PLoS One

Ultraviolet-B-mediated induction of protein–protein interactions in mammalian cells

(2013) Remco P. Crefcoeur et al.   Nature Communications

Designing Photoswitchable Peptides Using the AsLOV2 Domain

(2012) Oana I. Lungu et al.   CHEMISTRY & BIOLOGY

TULIPs: tunable, light-controlled interacting protein tags for cell biology

(2012) Devin Strickland et al.   NATURE METHODS

p53 Dynamics Control Cell Fate

(2012) J. E. Purvis et al.   SCIENCE

PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells

(2011) L Davies et al.   Cell Death & Disease

Single-cell NF-κB dynamics reveal digital activation and analogue information processing

(2010) Savaş Tay et al.   NATURE

The promise of optogenetics in cell biology: interrogating molecular circuits in space and time

(2010) Jared E Toettcher et al.   NATURE METHODS

Rationally improving LOV domain–based photoswitches

(2010) Devin Strickland et al.   NATURE METHODS

Expanding the Definition of the Classical Bipartite Nuclear Localization Signal

(2009) Allison Lange et al.   TRAFFIC

Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF

(2008) Joseph R. Pomerening et al.   MOLECULAR BIOLOGY OF THE CELL

Frequency-modulated nuclear localization bursts coordinate gene regulation

(2008) Long Cai et al.   NATURE