Epistasis and natural selection shape the mutational architecture of complex traits

WHY EPISTASIS IS IMPORTANT FOR SELECTION AND ADAPTATION

(2013) Thomas F. Hansen   EVOLUTION

The Evolution of Canalization and Evolvability in Stable and Fluctuating Environments

(2013) Arnaud Le Rouzic et al.   Evolutionary Biology

Compensatory Evolution and the Origins of Innovations

(2013) E. Rajon et al.   GENETICS

PHENOTYPIC PLASTICITY FACILITATES MUTATIONAL VARIANCE, GENETIC VARIANCE, AND EVOLVABILITY ALONG THE MAJOR AXIS OF ENVIRONMENTAL VARIATION

(2012) Jeremy A. Draghi et al.   EVOLUTION

Epistasis dominates the genetic architecture of Drosophila quantitative traits

(2012) W. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutational robustness can facilitate adaptation

(2010) Jeremy A. Draghi et al.   NATURE

Common SNPs explain a large proportion of the heritability for human height

(2010) Jian Yang et al.   NATURE GENETICS

Evolution of adaptive phenotypic variation patterns by direct selection for evolvability

(2010) M. Pavlicev et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Robustness and Evolvability

(2010) Joanna Masel et al.   TRENDS IN GENETICS

GENETIC ARCHITECTURE AND POSTZYGOTIC REPRODUCTIVE ISOLATION: EVOLUTION OF BATESON-DOBZHANSKY-MULLER INCOMPATIBILITIES IN A POLYGENIC MODEL

(2009) Janna L. Fierst et al.   EVOLUTION

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Common disorders are quantitative traits

(2009) Robert Plomin et al.   NATURE REVIEWS GENETICS

The genetics of quantitative traits: challenges and prospects

(2009) Trudy F. C. Mackay et al.   NATURE REVIEWS GENETICS

Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems

(2008) Patrick C. Phillips   NATURE REVIEWS GENETICS

Genetic Mapping in Human Disease

(2008) D. Altshuler et al.   SCIENCE

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics

Robustness and evolvability: a paradox resolved

(2007) A. Wagner   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES