Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53
Published 2013 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Computational identification of a transiently open L1/S3 pocket for reactivation of mutant p53
Authors
Keywords
-
Journal
Nature Communications
Volume 4, Issue 1, Pages -
Publisher
Springer Nature
Online
2013-01-29
DOI
10.1038/ncomms2361
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Allele-Specific p53 Mutant Reactivation
- (2012) Xin Yu et al. CANCER CELL
- Halogen-Enriched Fragment Libraries as Leads for Drug Rescue of Mutant p53
- (2012) Rainer Wilcken et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Using targeted transgenic reporter mice to study promoter-specific p53 transcriptional activity
- (2012) A. M. Goh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity
- (2011) Tom J Petty et al. EMBO JOURNAL
- Interaction of the p53 DNA-Binding Domain with Its N-Terminal Extension Modulates the Stability of the p53 Tetramer
- (2011) Eviatar Natan et al. JOURNAL OF MOLECULAR BIOLOGY
- Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural CDKN1A (p21) p53-Response Element
- (2011) S. Emamzadah et al. MOLECULAR CANCER RESEARCH
- Ensemble-Based Computational Approach Discriminates Functional Activity of p53 Cancer and Rescue Mutants
- (2011) Özlem Demir et al. PLoS Computational Biology
- All-codon scanning identifies p53 cancer rescue mutations
- (2010) Roberta Baronio et al. NUCLEIC ACIDS RESEARCH
- Pharmacological reactivation of mutant p53: from protein structure to the cancer patient
- (2010) K G Wiman ONCOGENE
- Stabilization of mutant p53 via alkylation of cysteines and effects on DNA binding
- (2010) Joel L. Kaar et al. PROTEIN SCIENCE
- The Tumor Suppressor p53: From Structures to Drug Discovery
- (2010) A. C. Joerger et al. Cold Spring Harbor Perspectives in Biology
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques
- (2009) Ryan Brenke et al. BIOINFORMATICS
- Fpocket: An open source platform for ligand pocket detection
- (2009) Vincent Le Guilloux et al. BMC BIOINFORMATICS
- PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain
- (2009) Jeremy M.R. Lambert et al. CANCER CELL
- Predicting Positive p53 Cancer Rescue Regions Using Most Informative Positive (MIP) Active Learning
- (2009) Samuel A. Danziger et al. PLoS Computational Biology
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- An improved relaxed complex scheme for receptor flexibility in computer-aided drug design
- (2008) Rommie E. Amaro et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Ensemble-Based Virtual Screening Reveals Potential Novel Antiviral Compounds for Avian Influenza Neuraminidase
- (2008) Lily S. Cheng et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mutant p53 targeting by the low molecular weight compound STIMA-1
- (2008) Nicole Zache et al. Molecular Oncology
- Crystal structure of a p53 core tetramer bound to DNA
- (2008) K A Malecka et al. ONCOGENE
- Targeted rescue of a destabilized mutant of p53 by an in silico screened drug
- (2008) F. M. Boeckler et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search