Structure of the pentameric ligand-gated ion channel ELIC cocrystallized with its competitive antagonist acetylcholine

Overview of theCCP4 suite and current developments

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Principles of activation and permeation in an anion-selective Cys-loop receptor

(2011) Ryan E. Hibbs et al.   NATURE

Ligand-binding domain of an α7-nicotinic receptor chimera and its complex with agonist

(2011) Shu-Xing Li et al.   NATURE NEUROSCIENCE

A Structural and Mutagenic Blueprint for Molecular Recognition of Strychnine and d-Tubocurarine by Different Cys-Loop Receptors

(2011) Marijke Brams et al.   PLOS BIOLOGY

Ligand Activation of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC

(2011) Iwan Zimmermann et al.   PLOS BIOLOGY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Allosteric Receptors: From Electric Organ to Cognition

(2010) Jean-Pierre Changeux   Annual Review of Pharmacology and Toxicology

Crystal Structures of a Cysteine-modified Mutant in Loop D of Acetylcholine-binding Protein

(2010) Marijke Brams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis of function in Cys-loop receptors

(2010) Andrew J. Thompson et al.   QUARTERLY REVIEWS OF BIOPHYSICS

Binding, activation and modulation of Cys-loop receptors

(2010) Paul S. Miller et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Gating of nicotinic ACh receptors: latest insights into ligand binding and function

(2009) Jerrel L. Yakel   JOURNAL OF PHYSIOLOGY-LONDON

The gating isomerization of neuromuscular acetylcholine receptors

(2009) Anthony Auerbach   JOURNAL OF PHYSIOLOGY-LONDON

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system

(2009) Antoine Taly et al.   NATURE REVIEWS DRUG DISCOVERY

Crystal Structures of the Choline/Acetylcholine Substrate-binding Protein ChoX fromSinorhizobium melilotiin the Liganded and Unliganded-Closed States

(2008) Christine Oswald et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a potentially open state of a proton-activated pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

X-ray structure of a pentameric ligand-gated ion channel in an apparently open conformation

(2008) Nicolas Bocquet et al.   NATURE

X-ray structure of a prokaryotic pentameric ligand-gated ion channel

(2008) Ricarda J. C. Hilf et al.   NATURE

A conserved salt bridge critical for GABAA receptor function and loop C dynamics

(2008) S. P. Venkatachalan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA