The synergistic effects of traditional Chinese herbs and radiotherapy for cancer treatment

Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer

(2014) Kwang Woon Kim et al.   Autophagy

ON-III inhibits erbB-2 tyrosine kinase receptor signal pathway and triggers apoptosis through induction of Bim in breast cancer cells

(2010) Dan-Dan Li et al.   CANCER BIOLOGY & THERAPY

The radiosensitization effects of Endostar on human lung squamous cancer cells H-520

(2010) Zhen Y You et al.   Cancer Cell International

Cyclooxygenase-2 Inhibitor NS398 Enhances Radiosensitivity of Radioresistant Esophageal Cancer Cells by Inhibiting AKT Activation and Inducing Apoptosis

(2010) Shao-Min Che et al.   CANCER INVESTIGATION

Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway

(2010) X. Pang et al.   CANCER RESEARCH

Caffeine enhances radiosensitization to orthotopic transplant LM3 hepatocellular carcinoma in vivo

(2010) Tie-Jun Wang et al.   CANCER SCIENCE

Cantharidin, a potent and selective PP2A inhibitor, induces an oxidative stress-independent growth inhibition of pancreatic cancer cells through G2/M cell-cycle arrest and apoptosis

(2010) Wei Li et al.   CANCER SCIENCE

Crosstalk between apoptosis and autophagy within the Beclin 1 interactome

(2010) Maria Chiara Maiuri et al.   EMBO JOURNAL

Icariin exterts negative effects on human gastric cancer cell invasion and migration by vasodilator-stimulated phosphoprotein via Rac1 pathway

(2010) Yongping Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

HIF-1 and NDRG2 contribute to hypoxia-induced radioresistance of cervical cancer Hela cells

(2010) Junye Liu et al.   EXPERIMENTAL CELL RESEARCH

Flavokawain B, a novel chalcone from Alpinia pricei Hayata with potent apoptotic activity: Involvement of ROS and GADD153 upstream of mitochondria-dependent apoptosis in HCT116 cells

(2010) Yu-Feng Kuo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Response to “Radiation Therapeutic Gain and Asian Botanicals,” by Stephen Sagar

(2010) Brian D. Lawenda   INTEGRATIVE CANCER THERAPIES

Inhibition of STAT3 and ErbB2 Suppresses Tumor Growth, Enhances Radiosensitivity, and Induces Mitochondria-Dependent Apoptosis in Glioma Cells

(2010) Ling Gao et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Osthole Suppresses Fatty Acid Synthase Expression in HER2-Overexpressing Breast Cancer Cells through Modulating Akt/mTOR Pathway

(2010) Victor Chia-Hsiang Lin et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Celastrol, a Triterpene, Enhances TRAIL-induced Apoptosis through the Down-regulation of Cell Survival Proteins and Up-regulation of Death Receptors

(2010) Bokyung Sung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment

(2010) Shelly Adi-Harel et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Photo-activated pheophorbide-a, an active component of Scutellaria barbata, enhances apoptosis via the suppression of ERK-mediated autophagy in the estrogen receptor-negative human breast adenocarcinoma cells MDA-MB-231

(2010) Ngoc-Ha Bui-Xuan et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cordyceps pruinosa extracts induce apoptosis of HeLa cells by a caspase dependent pathway

(2010) Ho Gyoung Kim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Cinobufacini, an aqueous extract from Bufo bufo gargarizans Cantor, induces apoptosis through a mitochondria-mediated pathway in human hepatocellular carcinoma cells

(2010) Fanghua Qi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antiproliferative and Antitumorigenic Activity of Toona sinensis Leaf Extracts in Lung Adenocarcinoma

(2010) Chih-Jen Yang et al.   JOURNAL OF MEDICINAL FOOD

Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis

(2010) B. Y. K. Law et al.   MOLECULAR CANCER THERAPEUTICS

Triterpenes FromGanoderma LucidumInduce Autophagy in Colon Cancer Through the Inhibition of p38 Mitogen-Activated Kinase (p38 MAPK)

(2010) Anita Thyagarajan et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Plumbagin, Isolated from Plumbago zeylanica, Induces Cell Death through Apoptosis in Human Pancreatic Cancer Cells

(2010) Chien-An Chen et al.   PANCREATOLOGY

Mice drinking goji berry juice (Lycium barbarum) are protected from UV radiation-induced skin damage via antioxidant pathways

(2010) Vivienne E. Reeve et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Synergistic antitumoral activity and induction of apoptosis by novel pan Bcl-2 proteins inhibitor apogossypolone with adriamycin in human hepatocellular carcinoma

(2009) Jin-xia Mi et al.   ACTA PHARMACOLOGICA SINICA

GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms

(2009) Hua Xie et al.   ACTA PHARMACOLOGICA SINICA

Casticin induces leukemic cell death through apoptosis and mitotic catastrophe

(2009) Jia-Kun Shen et al.   ANNALS OF HEMATOLOGY

A proteomic study on a human osteosarcoma cell line Saos-2 treated with diallyl trisulfide

(2009) Yong Kui Zhang et al.   ANTI-CANCER DRUGS

Antroquinonol displays anticancer potential against human hepatocellular carcinoma cells: A crucial role of AMPK and mTOR pathways

(2009) Po-Cheng Chiang et al.   BIOCHEMICAL PHARMACOLOGY

HDAC Inhibitor, Valproic Acid, Induces p53-Dependent Radiosensitization of Colon Cancer Cells

(2009) Xufeng Chen et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Corosolic acid induces apoptosis through mitochondrial pathway and caspases activation in human cervix adenocarcinoma HeLa cells

(2009) Yanfeng Xu et al.   CANCER LETTERS

Waltonitone induces human hepatocellular carcinoma cells apoptosis in vitro and in vivo

(2009) Zhang Zhang et al.   CANCER LETTERS

Effect of Yangyin Humo Decoction (养阴护膜饮) on oral mucomembranous reaction to radiotherapy

(2009) An-wei Dai et al.   Chinese Journal of Integrative Medicine

Combined Bcl-2/Mammalian Target of Rapamycin Inhibition Leads to Enhanced Radiosensitization via Induction of Apoptosis and Autophagy in Non-Small Cell Lung Tumor Xenograft Model

(2009) K. W. Kim et al.   CLINICAL CANCER RESEARCH

Silencing of Heat Shock Protein 70 Expression Enhances Radiotherapy Efficacy and Inhibits Cell Invasion in Endometrial Cancer Cell Line

(2009) Xue-lian Du et al.   CROATIAN MEDICAL JOURNAL

Suppression of human lung cancer cell growth and migration by berbamine

(2009) Huiying Duan et al.   CYTOTECHNOLOGY

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

(2009) Einat Zalckvar et al.   EMBO REPORTS

SYUNZ-16, a newly synthesized alkannin derivative, induces tumor cells apoptosis and suppresses tumor growth through inhibition of PKB/AKT kinase activity and blockade of AKT/FOXO signal pathway

(2009) Rong Deng et al.   INTERNATIONAL JOURNAL OF CANCER

Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl-2 and enhancing caspase-3 activity in human malignant melanoma A375 cells

(2009) Xiaoyuan Xu et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling

(2009) Elena V. Efimova et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Licorice and Licochalcone-A Induce Autophagy in LNCaP Prostate Cancer Cells by Suppression of Bcl-2 Expression and the mTOR Pathway

(2009) Yi-Te Yo et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anticancer Effects of Flavonoid Derivatives Isolated from Millettia reticulata Benth in SK-Hep-1 Human Hepatocellular Carcinoma Cells

(2009) Song-Chwan Fang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Berbamine induces Fas-mediated apoptosis in human hepatocellular carcinoma HepG2 cells and inhibits its tumor growth in nude mice

(2009) Guan-Yu Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

In vitro and in vivo anti-photoaging effects of an isoflavone extract from soybean cake

(2009) Tsu-Man Chiu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Effects of Gekko sulfated polysaccharide–protein complex on human hepatoma SMMC-7721 cells: Inhibition of proliferation and migration

(2009) Dan Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

The antitumoral effect of Paris Saponin I associated with the induction of apoptosis through the mitochondrial pathway

(2009) X. Xiao et al.   MOLECULAR CANCER THERAPEUTICS

PP2A regulates ionizing radiation-induced apoptosis through Ser46 phosphorylation of p53

(2009) J. Mi et al.   MOLECULAR CANCER THERAPEUTICS

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Adenovirus-mediated siRNA targeting Mcl-1 gene increases radiosensitivity of pancreatic carcinoma cells in vitro and in vivo

(2009) Xiang Guoan et al.   SURGERY

Inhibition of expression of anti-apoptotic protein Bcl-2 and induction of cell death in radioresistant human prostate adenocarcinoma cell line (PC-3) by methyl jasmonate

(2008) Daniel Ezekwudo et al.   CANCER LETTERS

Combination treatment with arsenic trioxide and irradiation enhances apoptotic effects in U937 cells through increased mitotic arrest and ROS generation

(2008) Sheng-Yow Ho et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Alpinia pricei rhizome extracts induce apoptosis of human carcinoma KB cells via a mitochondria-dependent apoptotic pathway

(2008) Hsin-Ling Yang et al.   FOOD AND CHEMICAL TOXICOLOGY

Flavopiridol Potentiates the Cytotoxic Effects of Radiation in Radioresistant Tumor Cells in Which p53 is Mutated or Bcl-2 is Overexpressed

(2008) Takamitsu Hara et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Involvement of Caspases and Apoptosis-Inducing Factor in Bufotalin-Induced Apoptosis of Hep 3B Cells

(2008) Chun-Li Su et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cells

(2008) Ning Wang et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

ARF Induces Autophagy by Virtue of Interaction with Bcl-xl

(2008) Julia Pimkina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ganoderma tsugae extracts inhibit colorectal cancer cell growth via G2/M cell cycle arrest

(2008) Shih-Chung Hsu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Berberine prevents UV-induced MMP-1 and reduction of type I procollagen expression in human dermal fibroblasts

(2008) Sangmin Kim et al.   PHYTOMEDICINE

Identification of CD133-Positive Radioresistant Cells in Atypical Teratoid/ Rhabdoid Tumor

(2008) Shih-Hwa Chiou et al.   PLoS One

Enhanced induction of apoptosis in a radio-resistant bladder tumor cell line by combined treatments with X-rays and wortmannin

(2008) Trinidad Ortiz et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Antitumor effect and mechanism of Gecko on human esophageal carcinoma cell lines in vitro and xenografted sarcoma 180 in Kunming mice

(2008) Fei Liu et al.   WORLD JOURNAL OF GASTROENTEROLOGY