Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer

Low TLR9 expression defines an aggressive subtype of triple-negative breast cancer

(2012) Johanna Tuomela et al.   BREAST CANCER RESEARCH AND TREATMENT

Triple Negative Breast Cancer: From Molecular Portrait to Therapeutic Intervention

(2012) Pietro Carotenuto et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Targeting Toll-like receptors by chloroquine protects mice from experimental cerebral malaria

(2012) Xiaotong Zhu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The p53-independent induction of apoptosis in breast cancer cells in response to proteasome inhibitor bortezomib

(2012) Azmi Yerlikaya et al.   TUMOR BIOLOGY

Akt and p53 are potential mediators of reduced mammary tumor growth by Chloroquine and the mTOR inhibitor RAD001

(2011) Christian R. Loehberg et al.   BIOCHEMICAL PHARMACOLOGY

Estrogen receptor-α and sex steroid hormones regulate Toll-like receptor-9 expression and invasive function in human breast cancer cells

(2011) Jouko Sandholm et al.   BREAST CANCER RESEARCH AND TREATMENT

Repositioning chloroquine and metformin to eliminate cancer stem cell traits in pre-malignant lesions

(2011) Alejandro Vazquez-Martin et al.   DRUG RESISTANCE UPDATES

Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines

(2011) A. Kuznik et al.   JOURNAL OF IMMUNOLOGY

Triple-Negative Breast Cancer

(2010) Anthony D. Elias   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Antitumor and antimetastatic activities of chloroquine diphosphate in a murine model of breast cancer

(2010) Pei-Du Jiang et al.   BIOMEDICINE & PHARMACOTHERAPY

Design and synthesis of chloroquine analogs with anti-breast cancer property

(2010) V.R. Solomon et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Aspirin: Old drug, new uses and challenges*

(2010) Neville D Yeomans   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Malignant Precursor Cells Pre-Exist in Human Breast DCIS and Require Autophagy for Survival

(2010) Virginia Espina et al.   PLoS One

Hydroxychloroquine, chloroquine, and all-trans retinoic acid regulate growth, survival, and histone acetylation in breast cancer cells

(2009) Rayhana Rahim et al.   ANTI-CANCER DRUGS

Toll-like receptor 9 agonists promote IL-8 and TGF-β1production via activation of nuclear factor κB in PC-3 cells

(2009) Jin-ming Di et al.   CANCER GENETICS AND CYTOGENETICS

A threshold level of TLR9 mRNA predicts cellular responsiveness to CpG-ODN in haematological and non-haematological tumour cell lines

(2009) Areej Assaf et al.   CELLULAR IMMUNOLOGY

A 4-aminoquinoline derivative that markedly sensitizes tumor cell killing by Akt inhibitors with a minimum cytotoxicity to non-cancer cells

(2009) Changkun Hu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Toll-Like Receptor 9 Mediates CpG Oligonucleotide-Induced Cellular Invasion

(2008) J. M. Ilvesaro et al.   MOLECULAR CANCER RESEARCH