Do epigenetic drug treatments hold the key to killing cancer progenitor cells?

Cancer Development, Progression, and Therapy: An Epigenetic Overview

(2013) Sibaji Sarkar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A melanocyte lineage program confers resistance to MAP kinase pathway inhibition

(2013) Cory M. Johannessen et al.   NATURE

TGF-β1 regulates cell fate during epithelial–mesenchymal transition by upregulating survivin

(2013) J Lee et al.   Cell Death & Disease

Demethylation and re-expression of epigenetically silenced tumor suppressor genes: sensitization of cancer cells by combination therapy

(2013) Sibaji Sarkar et al.   Epigenomics

Identifying Division Symmetry of Mouse Embryonic Stem Cells: Negative Impact of DNA Methyltransferases on Symmetric Self-Renewal

(2013) Lukasz Jasnos et al.   Stem Cell Reports

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

T-Oligos Inhibit Growth and Induce Apoptosis in Human Ovarian Cancer Cells

(2011) Sibaji Sarkar et al.   OLIGONUCLEOTIDES

Integrated Epigenetics of Human Breast Cancer: Synoptic Investigation of Targeted Genes, MicroRNAs and Proteins upon Demethylation Treatment

(2011) Ramin Radpour et al.   PLoS One

Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state

(2011) C. L. Chaffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer

(2011) R. A. Juergens et al.   Cancer Discovery

Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer

(2010) N. Matsumura et al.   GENOME RESEARCH

Cancer stem cells: the theory and perspectives in cancer therapy

(2010) Justyna Gil et al.   JOURNAL OF APPLIED GENETICS

Combination therapy of established cancer using a histone deacetylase inhibitor and a TRAIL receptor agonist

(2008) A. J. Frew et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA