In junk we trust: repetitive DNA, epigenetics and facioscapulohumeral muscular dystrophy

Altruistic functions for selfish DNA

(2011) Geoffrey J. Faulkner et al.   CELL CYCLE

Transcriptional regulation through noncoding RNAs and epigenetic modifications

(2010) Riki Kurokawa et al.   RNA Biology

RNA regulation of epigenetic processes

(2009) John S. Mattick et al.   BIOESSAYS

Remodeling of the chromatin structure of the facioscapulohumeral muscular dystrophy (FSHD) locus and upregulation of FSHD-related gene 1 (FRG1) expression during human myogenic differentiation

(2009) Beatrice Bodega et al.   BMC BIOLOGY

CTCF: Master Weaver of the Genome

(2009) Jennifer E. Phillips et al.   CELL

How cohesin and CTCF cooperate in regulating gene expression

(2009) Kerstin S. Wendt et al.   CHROMOSOME RESEARCH

The role of RNP biogenesis in spinal muscular atrophy

(2009) Ashwin Chari et al.   CURRENT OPINION IN CELL BIOLOGY

FSHD region gene 1 (FRG1) is crucial for angiogenesis linking FRG1 to facioscapulohumeral muscular dystrophy-associated vasculopathy

(2009) R. D. Wuebbles et al.   Disease Models & Mechanisms

Identification of a perinuclear positioning element in human subtelomeres that requires A-type lamins and CTCF

(2009) Alexandre Ottaviani et al.   EMBO JOURNAL

Comprehensive expression analysis of FSHD candidate genes at the mRNA and protein level

(2009) Rinse Klooster et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Analysis of allele-specific RNA transcription in FSHD by RNA-DNA FISH in single myonuclei

(2009) Peter S Masny et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Common epigenetic changes of D4Z4 in contraction-dependent and contraction-independent FSHD

(2009) Jessica C. de Greef et al.   HUMAN MUTATION

Many paths to one goal? The proteins that recognize methylated DNA in eukaryotes

(2009) Nobuhiro Sasai et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Laminopathies and the long strange trip from basic cell biology to therapy

(2009) Howard J. Worman et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-coding RNAs: regulators of disease

(2009) Ryan J Taft et al.   JOURNAL OF PATHOLOGY

Loss of YY1 Impacts the Heterochromatic State and Meiotic Double-Strand Breaks during Mouse Spermatogenesis

(2009) S. Wu et al.   MOLECULAR AND CELLULAR BIOLOGY

Quality of life and pain in patients with facioscapulohumeral muscular dystrophy

(2009) Luca Padua et al.   MUSCLE & NERVE

DNaseI hypersensitivity at gene-poor, FSH dystrophy-linked 4q35.2

(2009) Xueqing Xu et al.   NUCLEIC ACIDS RESEARCH

Biphasic Myopathic Phenotype of Mouse DUX, an ORF within Conserved FSHD-Related Repeats

(2009) Darko Bosnakovski et al.   PLoS One

DUX4c Is Up-Regulated in FSHD. It Induces the MYF5 Protein and Human Myoblast Proliferation

(2009) Eugénie Ansseau et al.   PLoS One

Transcriptional regulation differs in affected facioscapulohumeral muscular dystrophy patients compared to asymptomatic related carriers

(2009) P. Arashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emergence of lineage-specific chromosomal topologies from coordinate gene regulation

(2009) I. Rajapakse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Specific Loss of Histone H3 Lysine 9 Trimethylation and HP1γ/Cohesin Binding at D4Z4 Repeats Is Associated with Facioscapulohumeral Dystrophy (FSHD)

(2009) Weihua Zeng et al.   PLoS Genetics

The D4Z4 Macrosatellite Repeat Acts as a CTCF and A-Type Lamins-Dependent Insulator in Facio-Scapulo-Humeral Dystrophy

(2009) Alexandre Ottaviani et al.   PLoS Genetics

Chronic Pain in Persons With Myotonic Dystrophy and Facioscapulohumeral Dystrophy

(2008) Mark P. Jensen et al.   ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION

Nuclear architecture and gene regulation

(2008) Elena Fedorova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Towards an integrated understanding of the structure and mechanics of the cell nucleus

(2008) Amy C. Rowat et al.   BIOESSAYS

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

HP1: a functionally multifaceted protein

(2008) Laura Fanti et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Muscular dystrophy candidate gene FRG1 is critical for muscle development

(2008) Meredith L. Hanel et al.   DEVELOPMENTAL DYNAMICS

An isogenetic myoblast expression screen identifies DUX4-mediated FSHD-associated molecular pathologies

(2008) Darko Bosnakovski et al.   EMBO JOURNAL

Facioscapulohumeral muscular dystrophy: hearing loss and other atypical features of patients with large 4q35 deletions

(2008) C. P. Trevisan et al.   EUROPEAN JOURNAL OF NEUROLOGY

Epigenetic Silencing of CCAAT/Enhancer-binding Protein δ Activity by YY1/Polycomb Group/DNA Methyltransferase Complex

(2008) Chiung-Yuan Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic mechanisms of facioscapulohumeral muscular dystrophy

(2008) Jessica C. de Greef et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Isolation of an active step I spliceosome and composition of its RNP core

(2008) Sergey Bessonov et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

Is there a code embedded in proteins that is based on post-translational modifications?

(2008) Robert J. Sims et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Epigenetics of a tandem DNA repeat: chromatin DNaseI sensitivity and opposite methylation changes in cancers

(2008) Koji Tsumagari et al.   NUCLEIC ACIDS RESEARCH

A Functional Role for 4qA/B in the Structural Rearrangement of the 4q35 Region and in the Regulation of FRG1 and ANT1 in Facioscapulohumeral Dystrophy

(2008) Iryna Pirozhkova et al.   PLoS One

Facioscapulohumeral Dystrophy

(2007) Shree Pandya et al.   PHYSICAL THERAPY