B cell autophagy mediates TLR7-dependent autoimmunity and inflammation

The autophagy geneATG5plays an essential role in B lymphocyte development

(2014) Brian C. Miller et al.   Autophagy

Impact of interferon-  on hematopoiesis

(2014) A. M. de Bruin et al.   BLOOD

TLR Agonists Promote Marginal Zone B Cell Activation and Facilitate T-Dependent IgM Responses

(2014) A. V. Rubtsov et al.   JOURNAL OF IMMUNOLOGY

ATG5 regulates plasma cell differentiation

(2013) Kara L. Conway et al.   Autophagy

Genetic susceptibility to SLE: Recent progress from GWAS

(2013) Yong Cui et al.   JOURNAL OF AUTOIMMUNITY

Overexpression of TLR7 promotes cell-intrinsic expansion and autoantibody production by transitional T1 B cells

(2013) Natalia V. Giltiay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Increased Ribonuclease Expression Reduces Inflammation and Prolongs Survival in TLR7 Transgenic Mice

(2013) X. Sun et al.   JOURNAL OF IMMUNOLOGY

Plasma cells require autophagy for sustainable immunoglobulin production

(2013) Niccolò Pengo et al.   NATURE IMMUNOLOGY

Toll-like Receptor 7-Stimulated Tumor Necrosis Factor α Causes Bone Marrow Damage in Systemic Lupus Erythematosus

(2013) Haoyang Zhuang et al.   Arthritis & Rheumatology

Role of autophagy in immunity and autoimmunity, with a special focus on systemic lupus erythematosus

(2012) Marina Pierdominici et al.   FASEB JOURNAL

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

(2012) Jill Henault et al.   IMMUNITY

Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell-mediated autoimmunity

(2012) E. R. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The genomics of autoimmune disease in the era of genome-wide association studies and beyond

(2011) Christopher J. Lessard et al.   AUTOIMMUNITY REVIEWS

Chronic IFN-  production in mice induces anemia by reducing erythrocyte life span and inhibiting erythropoiesis through an IRF-1/PU.1 axis

(2011) S. F. Libregts et al.   BLOOD

Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking

(2011) Ryutaro Fukui et al.   IMMUNITY

Inflammatory Cytokines in Systemic Lupus Erythematosus

(2011) Kim Ohl et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Possible role of the JAK/STAT pathways in the regulation of T cell-interferon related genes in systemic lupus erythematosus

(2011) M Kawasaki et al.   LUPUS

Systemic Lupus Erythematosus

(2011) George C. Tsokos   NEW ENGLAND JOURNAL OF MEDICINE

Association of TLR7 copy number variation with susceptibility to childhood-onset systemic lupus erythematosus in Mexican population

(2010) H. Garcia-Ortiz et al.   ANNALS OF THE RHEUMATIC DISEASES

Endogenous retroviral pathogenesis in lupus

(2010) Andras Perl et al.   CURRENT OPINION IN RHEUMATOLOGY

The interferon-α signature of systemic lupus erythematosus

(2010) G. Obermoser et al.   LUPUS

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

(2010) N. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogenesis of human systemic lupus erythematosus: recent advances

(2010) José C. Crispín et al.   TRENDS IN MOLECULAR MEDICINE

Epigenetics Lessons from Twins: Prospects for Autoimmune Disease

(2009) Esteban Ballestar   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

(2008) You-Me Kim et al.   NATURE

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

(2008) John B Harley et al.   NATURE GENETICS