Multiscale image-based modeling and simulation of gas flow and particle transport in the human lungs

Multiscale imaging and registration-driven model for pulmonary acinar mechanics in the mouse

(2013) Haribalan Kumar et al.   JOURNAL OF APPLIED PHYSIOLOGY

Performance of Combination Drug and Hygroscopic Excipient Submicrometer Particles from a Softmist Inhaler in a Characteristic Model of the Airways

(2012) P. Worth Longest et al.   ANNALS OF BIOMEDICAL ENGINEERING

Effect of Carrier Gas Properties on Aerosol Distribution in a CT-based Human Airway Numerical Model

(2012) Shinjiro Miyawaki et al.   ANNALS OF BIOMEDICAL ENGINEERING

Peripheral resistance: a link between global airflow obstruction and regional ventilation distribution

(2012) C. Wongviriyawong et al.   JOURNAL OF APPLIED PHYSIOLOGY

A multiscale MDCT image-based breathing lung model with time-varying regional ventilation

(2012) Youbing Yin et al.   JOURNAL OF COMPUTATIONAL PHYSICS

A computational model of the topographic distribution of ventilation in healthy human lungs

(2012) Annalisa J. Swan et al.   JOURNAL OF THEORETICAL BIOLOGY

Comparing MDI and DPI Aerosol Deposition Using In Vitro Experiments and a New Stochastic Individual Path (SIP) Model of the Conducting Airways

(2012) P. Worth Longest et al.   PHARMACEUTICAL RESEARCH

Comparative Computational Modeling of Airflows and Vapor Dosimetry in the Respiratory Tracts of Rat, Monkey, and Human

(2012) R. A. Corley et al.   TOXICOLOGICAL SCIENCES

In silico models of aerosol delivery to the respiratory tract — Development and applications

(2011) P. Worth Longest et al.   ADVANCED DRUG DELIVERY REVIEWS

Severe Asthma

(2011) Nizar N. Jarjour et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Simulating ventilation distribution in heterogenous lung injury using a binary tree data structure

(2011) Ashley A. Colletti et al.   COMPUTERS IN BIOLOGY AND MEDICINE

Convective flow dominates aerosol delivery to the lung segments

(2011) C. Darquenne et al.   JOURNAL OF APPLIED PHYSIOLOGY

Three-dimensional characterization of regional lung deformation

(2011) Ryan Amelon et al.   JOURNAL OF BIOMECHANICS

Why chaotic mixing of particles is inevitable in the deep lung

(2011) Akira Tsuda et al.   JOURNAL OF THEORETICAL BIOLOGY

Steady streaming: A key mixing mechanism in low-Reynolds-number acinar flows

(2011) Haribalan Kumar et al.   PHYSICS OF FLUIDS

The Onset of Turbulence in Pipe Flow

(2011) K. Avila et al.   SCIENCE

Regional Deposition of Particles in an Image-Based Airway Model: Large-Eddy Simulation and Left-Right Lung Ventilation Asymmetry

(2010) Andrew R. Lambert et al.   AEROSOL SCIENCE AND TECHNOLOGY

Characterization of Respiratory Drug Delivery with Enhanced Condensational Growth using an Individual Path Model of the Entire Tracheobronchial Airways

(2010) Geng Tian et al.   ANNALS OF BIOMEDICAL ENGINEERING

Numerical Study of High-Frequency Oscillatory Air Flow and Convective Mixing in a CT-Based Human Airway Model

(2010) Jiwoong Choi et al.   ANNALS OF BIOMEDICAL ENGINEERING

CFD simulation of particle deposition in a reconstructed human oral extrathoracic airway for air and helium–oxygen mixtures

(2010) J. Sandeau et al.   JOURNAL OF AEROSOL SCIENCE

Simulation of pulmonary air flow with a subject-specific boundary condition

(2010) Youbing Yin et al.   JOURNAL OF BIOMECHANICS

Image-based modeling of lung structure and function

(2010) Merryn H. Tawhai et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

A cubic B-spline-based hybrid registration of lung CT images for a dynamic airway geometric model with large deformation

(2010) Youbing Yin et al.   PHYSICS IN MEDICINE AND BIOLOGY

Validation of Computational Fluid Dynamics in CT-based Airway Models with SPECT/CT

(2010) Jan W. De Backer et al.   RADIOLOGY

Identification of Asthma Phenotypes Using Cluster Analysis in the Severe Asthma Research Program

(2009) Wendy C. Moore et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airflow and Particle Transport in the Human Respiratory System

(2009) C. Kleinstreuer et al.   Annual Review of Fluid Mechanics

Left-to-Right Asymmetry of Aerosol Deposition after Shallow Bolus Inhalation Depends on Lung Ventilation

(2009) Winfried Möller et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Supine and prone differences in regional lung density and pleural pressure gradients in the human lung with constant shape

(2009) Merryn H. Tawhai et al.   JOURNAL OF APPLIED PHYSIOLOGY

The effects of geometry on airflow in the acinar region of the human lung

(2009) Haribalan Kumar et al.   JOURNAL OF BIOMECHANICS

Mass preserving nonrigid registration of CT lung images using cubic B-spline

(2009) Youbing Yin et al.   MEDICAL PHYSICS

On intra- and intersubject variabilities of airflow in the human lungs

(2009) Jiwoong Choi et al.   PHYSICS OF FLUIDS

CFD Simulation of Aerosol Deposition in an Anatomically Based Human Large–Medium Airway Model

(2008) Baoshun Ma et al.   ANNALS OF BIOMEDICAL ENGINEERING

Targeted Drug-Aerosol Delivery in the Human Respiratory System

(2008) C. Kleinstreuer et al.   Annual Review of Biomedical Engineering

Fluid–structure interaction approaches on fixed grids based on two different domain decomposition ideas

(2008) Wolfgang A. Wall et al.   INTERNATIONAL JOURNAL OF COMPUTATIONAL FLUID DYNAMICS

Large eddy and detached eddy simulations of fluid flow and particle deposition in a human mouth–throat

(2008) S.T. Jayaraju et al.   JOURNAL OF AEROSOL SCIENCE

Computational model of airflow in upper 17 generations of human respiratory tract

(2008) T. Gemci et al.   JOURNAL OF BIOMECHANICS

Numerical investigation of the three-dimensional flow in a human lung model

(2008) Rainhill K. Freitas et al.   JOURNAL OF BIOMECHANICS

Asymmetry and transition to turbulence in a smooth axisymmetric constriction

(2008) J. VÉTEL et al.   JOURNAL OF FLUID MECHANICS

Role of mechanical stress in regulating airway surface hydration and mucus clearance rates

(2008) Brian Button et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Flow analyses in the lower airways: Patient-specific model and boundary conditions

(2007) J.W. De Backer et al.   MEDICAL ENGINEERING & PHYSICS