ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation

Human autophagy geneATG16L1is post-transcriptionally regulated byMIR142-3p

(2014) Zili Zhai et al.   Autophagy

Receptor-mediated mitophagy in yeast and mammalian systems

(2014) Lei Liu et al.   CELL RESEARCH

CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation

(2014) Pietri Puustinen et al.   JOURNAL OF CELL BIOLOGY

The interplay between autophagy and mitochondrial dysfunction in oxidative stress-induced cardiac aging and pathology

(2014) Stephanie E. Wohlgemuth et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Insights Into Echo-Attenuated Plaques, Echolucent Plaques, and Plaques With Spotty Calcification

(2014) Jun Pu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy

(2014) Guo Chen et al.   MOLECULAR CELL

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

(2014) Hannah C. Dooley et al.   MOLECULAR CELL

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

FIP200 regulates targeting of Atg16L1 to the isolation membrane

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Inhibition of serine/threonine protein phosphatase PP1 protects cardiomyocytes from tunicamycin-induced apoptosis and I/R through the upregulation of p-eIF2α

(2013) CHUN-LEI LIU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

(2013) Naonobu Fujita et al.   JOURNAL OF CELL BIOLOGY

Stroma Cell-Derived Factor-1α Signaling Enhances Calcium Transients and Beating Frequency in Rat Neonatal Cardiomyocytes

(2013) Ielham Hadad et al.   PLoS One

PTEN Increases Autophagy and Inhibits the Ubiquitin-Proteasome Pathway in Glioma Cells Independently of its Lipid Phosphatase Activity

(2013) Rajaa Errafiy et al.   PLoS One

Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy

(2012) Shu-Yong Lin et al.   Autophagy

Src Family Kinase Inhibitor PP2 Induces LC3 Conversion in a Manner That is Uncoupled from Autophagy and Increases Apoptosis in Multidrug-Resistant Cells

(2012) Yun-Ki Kim et al.   Biomolecules & Therapeutics

Phosphorylation of Atg5 by the Gadd45β–MEKK4-p38 pathway inhibits autophagy

(2012) E Keil et al.   CELL DEATH AND DIFFERENTIATION

Mechanism and functions of membrane binding by the Atg5-Atg12/Atg16 complex during autophagosome formation

(2012) Julia Romanov et al.   EMBO JOURNAL

Cardiomyocyte-expressed farnesoid-X-receptor is a novel apoptosis mediator and contributes to myocardial ischaemia/reperfusion injury

(2012) Jun Pu et al.   EUROPEAN HEART JOURNAL

Structural basis for protein phosphatase 1 regulation and specificity

(2012) Wolfgang Peti et al.   FEBS Journal

Downregulation of protein kinase CK2 induces autophagic cell death through modulation of the mTOR and MAPK signaling pathways in human glioblastoma cells

(2012) BIRGITTE B. OLSEN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Chikungunya virus–induced autophagy delays caspase-dependent cell death

(2012) Pierre-Emmanuel Joubert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CK2 and the regulation of the carbohydrate metabolism

(2012) Faizeh Al Quobaili et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Protein Phosphatase-1α Interacts with and Dephosphorylates Polycystin-1

(2012) Stephen C. Parnell et al.   PLoS One

Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates

(2012) Michael F. Chou et al.   PLoS One

NADP+ Binding to the Regulatory Subunit of Methionine Adenosyltransferase II Increases Intersubunit Binding Affinity in the Hetero-Trimer

(2012) Beatriz González et al.   PLoS One

Phosphorylation of CRN2 by CK2 regulates F-actin and Arp2/3 interaction and inhibits cell migration

(2012) Charles-Peter Xavier et al.   Scientific Reports

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

Autophagy: for better or for worse

(2011) Ellen Wirawan et al.   CELL RESEARCH

KIBRA Regulates Hippo Signaling Activity via Interactions with Large Tumor Suppressor Kinases

(2011) Ling Xiao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of PTP  as an autophagic phosphatase

(2011) K. R. Martin et al.   JOURNAL OF CELL SCIENCE

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

Serine 403 Phosphorylation of p62/SQSTM1 Regulates Selective Autophagic Clearance of Ubiquitinated Proteins

(2011) Gen Matsumoto et al.   MOLECULAR CELL

Intestinal homeostasis and its breakdown in inflammatory bowel disease

(2011) Kevin J. Maloy et al.   NATURE

Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas?

(2011) L. Emdad et al.   NEURO-ONCOLOGY

The period of the circadian oscillator is primarily determined by the balance between casein kinase 1 and protein phosphatase 1

(2011) H.-m. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts

(2011) Tina C Wan et al.   BMC Pharmacology & Toxicology

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

(2010) Y. Cheng et al.   CARDIOVASCULAR RESEARCH

Sphingosine-1-phosphate phosphohydrolase-1 regulates ER stress-induced autophagy

(2010) S Lépine et al.   CELL DEATH AND DIFFERENTIATION

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde

(2010) Heng Ma et al.   EUROPEAN HEART JOURNAL

The regulation of autophagy - unanswered questions

(2010) Y. Chen et al.   JOURNAL OF CELL SCIENCE

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites

(2010) Michael J Ragusa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Simultaneous Induction of Non-Canonical Autophagy and Apoptosis in Cancer Cells by ROS-Dependent ERK and JNK Activation

(2010) Chew Hooi Wong et al.   PLoS One

Autophagy genes mediate the effect of calcineurin on life span inC. elegans

(2009) Meenakshi Dwivedi et al.   Autophagy

Coordinated regulation of autophagy by p38α MAPK through mAtg9 and p38IP

(2009) Jemma L Webber et al.   EMBO JOURNAL

Regulation of Autophagy by the p300 Acetyltransferase

(2009) In Hye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The selectivity of inhibitors of protein kinase CK2: an update

(2008) Mario A. Pagano et al.   BIOCHEMICAL JOURNAL

Tyrosine 302 in RACK1 Is Essential for Insulin-like Growth Factor-I-mediated Competitive Binding of PP2A and β1 Integrin and for Tumor Cell Proliferation and Migration

(2008) Patrick A. Kiely et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase CK2, an important regulator of the inflammatory response?

(2008) Nishi N. Singh et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Protein phosphatase 1 regulates the phosphorylation state of the polarity scaffold Par-3

(2008) A. Traweger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA