PPARγAgonists in Adaptive Immunity: What Do Immune Disorders and Their Models Have to Tell Us?

IL-33 Induces Antigen-Specific IL-5+ T Cells and Promotes Allergic-Induced Airway Inflammation Independent of IL-4

(2014) M. Kurowska-Stolarska et al.   JOURNAL OF IMMUNOLOGY

The Peroxisome Proliferator-Activated Receptor   Agonist Rosiglitazone Ameliorates Murine Lupus by Induction of Adiponectin

(2014) T. Aprahamian et al.   JOURNAL OF IMMUNOLOGY

Autoimmune Memory T Helper 17 Cell Function and Expansion Are Dependent on Interleukin-23

(2013) Christopher J. Haines et al.   Cell Reports

Adaptive immunity in rheumatic diseases – Bystander or pathogenic player?

(2012) Hans Ulrich Scherer et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

IL-5 promotes induction of antigen-specific CD4+CD25+ T regulatory cells that suppress autoimmunity

(2012) G. T. Tran et al.   BLOOD

Regulatory T Cells Expressing PPAR-γ Control Inflammation in Obesity

(2012) Masahide Hamaguchi et al.   Cell Metabolism

Targeting Orphan Nuclear Receptors for Treatment of Metabolic Diseases and Autoimmunity

(2012) Thomas P. Burris et al.   CHEMISTRY & BIOLOGY

Pioglitazone, PPARγ Agonist, Attenuates Experimental Autoimmune Neuritis

(2012) Hhoonisha Ramkalawan et al.   INFLAMMATION

The nuclear receptor PPARs as important regulators of T-cell functions and autoimmune diseases

(2012) Je-Min Choi et al.   MOLECULES AND CELLS

A B cell explanation for autoimmune disease: the forbidden clone returns

(2012) Fiona McQueen   POSTGRADUATE MEDICAL JOURNAL

Thiazolidinediones and PPARγ agonists: time for a reassessment

(2012) Bertrand Cariou et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PPAR-γ agonists, mainly 15d-PGJ2, reduce eosinophil recruitment following allergen challenge

(2011) Thais S. Farnesi-de-Assunção et al.   CELLULAR IMMUNOLOGY

Nuclear receptors: TH 17 cell control from within

(2011) L. Klotz et al.   FEBS LETTERS

Peroxisome Proliferator-Activated Receptor γ Is Required for CD4 + T Cell-Mediated Lymphopenia-Associated Autoimmunity

(2011) William J. Housley et al.   JOURNAL OF IMMUNOLOGY

The Dysregulation of Cytokine Networks in Systemic Lupus Erythematosus

(2011) Sokratis A. Apostolidis et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

The Role of Cytokines in the Pathogenesis and Treatment of Systemic Lupus Erythematosus

(2011) Laurie S. Davis et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

PPARγ expression is increased in systemic lupus erythematosus patients and represses CD40/CD40L signaling pathway

(2011) DS Oxer et al.   LUPUS

The Nuclear Hormone Receptor PPARγas a Therapeutic Target in Major Diseases

(2011) Martina Victoria Schmidt et al.   TheScientificWorldJOURNAL

The Th1 life cycle: molecular control of IFN-γ to IL-10 switching

(2011) Andrew Cope et al.   TRENDS IN IMMUNOLOGY

Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis

(2010) Adriana M. C. Mus et al.   ARTHRITIS AND RHEUMATISM

The Role of T cell PPAR γ in mice with experimental inflammatory bowel disease

(2010) Amir J Guri et al.   BMC GASTROENTEROLOGY

Interferon-alpha, -beta and -gamma induce CXCL9 and CXCL10 secretion by human thyrocytes: Modulation by peroxisome proliferator-activated receptor-gamma agonists

(2010) Alessandro Antonelli et al.   CYTOKINE

Rituximab versus Cyclophosphamide for ANCA-Associated Vasculitis

(2010) John H. Stone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Regulation of T Helper 17 Cell Differentiation

(2010) Eun Sook Hwang   YONSEI MEDICAL JOURNAL

Rituximab in patients with primary progressive multiple sclerosis: Results of a randomized double-blind placebo-controlled multicenter trial

(2009) Kathleen Hawker et al.   ANNALS OF NEUROLOGY

Anti-allergic function and regulatory mechanisms of KR62980 in allergen-induced airway inflammation

(2009) Hee Yeon Won et al.   BIOCHEMICAL PHARMACOLOGY

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peroxisome Proliferator-Activated Receptor   Ligands Enhance Human B Cell Antibody Production and Differentiation

(2009) T. M. Garcia-Bates et al.   JOURNAL OF IMMUNOLOGY

Peroxisome Proliferator-Activated Receptor   Agonist Down-Regulates IL-17 Expression in a Murine Model of Allergic Airway Inflammation

(2009) S. J. Park et al.   JOURNAL OF IMMUNOLOGY

Regulatory T cells exert checks and balances on self tolerance and autoimmunity

(2009) Kajsa Wing et al.   NATURE IMMUNOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD4 T cells: fates, functions, and faults

(2008) J. Zhu et al.   BLOOD

Control of cytokine gene transcription in Th1 and Th2 cells

(2008) H. Bowen et al.   CLINICAL AND EXPERIMENTAL ALLERGY

The many faces of PPARγ: Anti-inflammatory by any means?

(2008) Attila Szanto et al.   IMMUNOBIOLOGY

Treating patients with lupus with B-cell depletion

(2008) DA Isenberg   LUPUS

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE