Update on Ppar and Nonalcoholic Fatty Liver Disease

Selective PPARγ modulator INT131 normalizes insulin signaling defects and improves bone mass in diet-induced obese mice

(2012) Dae Ho Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Use of thiazolidinediones and the risk of bladder cancer among people with type 2 diabetes: a meta-analysis

(2012) I. N. Colmers et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Nonalcoholic Fatty Liver Disease/Steatohepatitis: Epidemiology, Pathogenesis, Clinical Presentation and Treatment

(2012) Sandra Milic et al.   DIGESTIVE DISEASES

Genetically modified mouse models for the study of nonalcoholic fatty liver disease

(2012) Perumal Nagarajan   WORLD JOURNAL OF GASTROENTEROLOGY

Activation of peroxisome proliferator-activated receptor-γ by rosiglitazone improves lipid homeostasis at the adipose tissue-liver axis in ethanol-fed mice

(2011) Xiuhua Sun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genetic Variation in the Peroxisome Proliferator Activated Receptor-Gamma Gene Is Associated with Histologically Advanced NAFLD

(2011) Samer Gawrieh et al.   DIGESTIVE DISEASES AND SCIENCES

Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte- and macrophage-specific conditional knockouts

(2011) Eva Morán-Salvador et al.   FASEB JOURNAL

Diabetes: New conductors for the peroxisome proliferator-activated receptor γ (PPARγ) orchestra

(2011) Jonathan P. Whitehead   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

N-Acetylfarnesylcysteine Is a Novel Class of Peroxisome Proliferator-activated Receptor γ Ligand with Partial and Full Agonist Activityin Vitroandin Vivo

(2011) Kavita Bhalla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dietary Methionine Restriction Increases Fat Oxidation in Obese Adults with Metabolic Syndrome

(2011) Eric P. Plaisance et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Role of PPARg2 transcription factor in thiazolidinedione-induced insulin sensitization

(2011) Neha Saraf et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Animal models in nonalcoholic steatohepatitis research: utility and clinical translation

(2011) Quentin M. Anstee   LIVER INTERNATIONAL

PPARG gene Pro12Ala variant contributes to the development of non-alcoholic fatty liver in middle-aged and older Chinese population

(2011) Zhen Yang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Activation of Peroxisome Proliferator-Activated Receptor Gamma by Rosiglitazone Increases Sirt6 Expression and Ameliorates Hepatic Steatosis in Rats

(2011) Soo Jin Yang et al.   PLoS One

Lack of association between peroxisome proliferator-activated receptors alpha and gamma2 polymorphisms and progressive liver damage in patients with non-alcoholic fatty liver disease: a case control study

(2010) Paola Dongiovanni et al.   BMC GASTROENTEROLOGY

Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study

(2010) Christopher D. Williams et al.   GASTROENTEROLOGY

Peroxisome proliferators-activated receptor γ2 Pro12Ala variant is associated with body mass index in non-alcoholic fatty liver disease patients

(2010) A. C. Gupta et al.   Hepatology International

Selective modulation of PPARγ activity can lower plasma glucose without typical thiazolidinedione side-effects in patients with Type 2 diabetes

(2010) Fredrick L. Dunn et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Cysteine supplementation reverses methionine restriction effects on rat adiposity: significance of stearoyl-coenzyme A desaturase

(2010) Amany K. Elshorbagy et al.   JOURNAL OF LIPID RESEARCH

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

(2010) Jang Hyun Choi et al.   NATURE

Adenovirus-mediated peroxisome proliferator activated receptor gamma overexpression prevents nutritional fibrotic steatohepatitis in mice

(2010) Yue-Min Nan et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Pro12Ala polymorphism of the peroxisome proliferator-activated receptor γ2 in patients with fatty liver diseases

(2010) Johannes W Rey   WORLD JOURNAL OF GASTROENTEROLOGY

Histopathology of nonalcoholic fatty liver disease

(2010) Elizabeth M Brunt   WORLD JOURNAL OF GASTROENTEROLOGY

The role of the lipogenic pathway in the development of hepatic steatosis

(2009) C. Postic et al.   DIABETES & METABOLISM

Additive action of 11β-HSD1 inhibition and PPAR-γ agonism on hepatic steatosis and triglyceridemia in diet-induced obese rats

(2009) M Berthiaume et al.   INTERNATIONAL JOURNAL OF OBESITY

Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)

(2008) Masato Yoneda et al.   BMC GASTROENTEROLOGY

Hepatic Steatosis in Leptin-Deficient Mice Is Promoted by the PPARγ Target Gene Fsp27

(2008) Kimihiko Matsusue et al.   Cell Metabolism

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

Rosiglitazone prevents nutritional fibrosis and steatohepatitis in mice

(2008) Yue-Min Nan et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Mechanisms of Disease Progression in Nonalcoholic Fatty Liver Disease

(2008) Janice Jou et al.   SEMINARS IN LIVER DISEASE

Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease

(2008) Eric R Kallwitz et al.   WORLD JOURNAL OF GASTROENTEROLOGY