- Home
- Publications
- Publication Search
- Publication Details
Title
Molecular genetics of high-risk chronic lymphocytic leukemia
Authors
Keywords
-
Journal
Expert Review of Hematology
Volume 5, Issue 6, Pages 593-602
Publisher
Informa UK Limited
Online
2012-12-08
DOI
10.1586/ehm.12.58
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Risk categories and refractory CLL in the era of chemoimmunotherapy
- (2012) T. Zenz et al. BLOOD
- Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
- (2012) D. Rossi et al. BLOOD
- The B-cell receptor signaling pathway as a therapeutic target in CLL
- (2012) J. A. Woyach et al. BLOOD
- Different impact of NOTCH1 and SF3B1 mutations on the risk of chronic lymphocytic leukemia transformation to Richter syndrome
- (2012) Davide Rossi et al. BRITISH JOURNAL OF HAEMATOLOGY
- Splice Modulating Therapies for Human Disease
- (2012) Pietro Spitali et al. CELL
- Different distribution of NOTCH1 mutations in chronic lymphocytic leukemia with isolated trisomy 12 or associated with other chromosomal alterations
- (2012) Cristina López et al. GENES CHROMOSOMES & CANCER
- Novel Targeted Agents and the Need to Refine Clinical End Points in Chronic Lymphocytic Leukemia
- (2012) Bruce D. Cheson et al. JOURNAL OF CLINICAL ONCOLOGY
- Alemtuzumab in Combination With Methylprednisolone Is a Highly Effective Induction Regimen for Patients With Chronic Lymphocytic Leukemia and Deletion of TP53: Final Results of the National Cancer Research Institute CLL206 Trial
- (2012) Andrew R. Pettitt et al. JOURNAL OF CLINICAL ONCOLOGY
- ERIC recommendations on TP53 mutation analysis in chronic lymphocytic leukemia
- (2012) S Pospisilova et al. LEUKEMIA
- Therapeutic approaches to modulating Notch signaling: Current challenges and future prospects
- (2012) Casper Groth et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- NOTCH1 mutations in CLL associated with trisomy 12
- (2011) V. Balatti et al. BLOOD
- Alteration of BIRC3 and multiple other NF- B pathway genes in splenic marginal zone lymphoma
- (2011) D. Rossi et al. BLOOD
- Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
- (2011) D. Rossi et al. BLOOD
- Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia
- (2011) D. Rossi et al. BLOOD
- The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation
- (2011) D. Rossi et al. BLOOD
- ATM gene alterations in chronic lymphocytic leukemia patients induce a distinct gene expression profile and predict disease progression
- (2011) A. Guarini et al. HAEMATOLOGICA
- ATM germline heterozygosity does not play a role in chronic lymphocytic leukemia initiation but influences rapid disease progression through loss of the remaining ATM allele
- (2011) A. Skowronska et al. HAEMATOLOGICA
- Analysis of NOTCH1 mutations in monoclonal B-cell lymphocytosis
- (2011) S. Rasi et al. HAEMATOLOGICA
- NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL
- (2011) I. Del Giudice et al. HAEMATOLOGICA
- Missense Mutations Located in Structural p53 DNA-Binding Motifs Are Associated With Extremely Poor Survival in Chronic Lymphocytic Leukemia
- (2011) Martin Trbusek et al. JOURNAL OF CLINICAL ONCOLOGY
- Mutational Status of theTP53Gene As a Predictor of Response and Survival in Patients With Chronic Lymphocytic Leukemia: Results From the LRF CLL4 Trial
- (2011) David Gonzalez et al. JOURNAL OF CLINICAL ONCOLOGY
- Oncogenic and tumor suppressor functions of Notch in cancer: it’s NOTCH what you think: Table I.
- (2011) Camille Lobry et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Analysis of the chronic lymphocytic leukemia coding genome: role ofNOTCH1mutational activation
- (2011) Giulia Fabbri et al. JOURNAL OF EXPERIMENTAL MEDICINE
- T Cell Lineage Commitment: Identity and Renunciation
- (2011) E. V. Rothenberg JOURNAL OF IMMUNOLOGY
- Frequent pathway mutations of splicing machinery in myelodysplasia
- (2011) Kenichi Yoshida et al. NATURE
- Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
- (2011) Xose S. Puente et al. NATURE
- Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
- (2011) Víctor Quesada et al. NATURE GENETICS
- SomaticSF3B1Mutation in Myelodysplasia with Ring Sideroblasts
- (2011) E. Papaemmanuil et al. NEW ENGLAND JOURNAL OF MEDICINE
- SF3B1and Other Novel Cancer Genes in Chronic Lymphocytic Leukemia
- (2011) Lili Wang et al. NEW ENGLAND JOURNAL OF MEDICINE
- Understanding and Managing Ultra High-Risk Chronic Lymphocytic Leukemia
- (2011) S. Stilgenbauer et al. Hematology-American Society of Hematology Education Program
- Is the Aberrant Expression of p53 by Immunocytochemistry a Surrogate Marker ofTP53Mutation and/or Deletion in Chronic Lymphocytic Leukemia?
- (2010) Marilisa Marinelli et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Functions of Notch Signaling in the Immune System: Consensus and Controversies
- (2010) Julie S. Yuan et al. Annual Review of Immunology
- The lymph node microenvironment promotes B-cell receptor signaling, NF- B activation, and tumor proliferation in chronic lymphocytic leukemia
- (2010) Y. Herishanu et al. BLOOD
- 17-DMAG targets the nuclear factor- B family of proteins to induce apoptosis in chronic lymphocytic leukemia: clinical implications of HSP90 inhibition
- (2010) E. Hertlein et al. BLOOD
- Allogeneic stem cell transplantation provides durable disease control in poor-risk chronic lymphocytic leukemia: long-term clinical and MRD results of the German CLL Study Group CLL3X trial
- (2010) P. Dreger et al. BLOOD
- Molecular pathogenesis and targeted therapies for NOTCH1-induced T-cell acute lymphoblastic leukemia
- (2010) Maddalena Paganin et al. BLOOD REVIEWS
- NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL
- (2010) Paolo Sportoletti et al. BRITISH JOURNAL OF HAEMATOLOGY
- Interaction with Vascular Endothelium Enhances Survival in Primary Chronic Lymphocytic Leukemia Cells via NF- B Activation and De novo Gene Transcription
- (2010) A. G. S. Buggins et al. CANCER RESEARCH
- Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged
- (2010) C. J. David et al. GENES & DEVELOPMENT
- TP53Mutation and Survival in Chronic Lymphocytic Leukemia
- (2010) Thorsten Zenz et al. JOURNAL OF CLINICAL ONCOLOGY
- Notch signalling in T-cell lymphoblastic leukaemia/lymphoma and other haematological malignancies
- (2010) Jon C Aster et al. JOURNAL OF PATHOLOGY
- Addition of rituximab to fludarabine and cyclophosphamide in patients with chronic lymphocytic leukaemia: a randomised, open-label, phase 3 trial
- (2010) M Hallek et al. LANCET
- TP53 mutation profile in chronic lymphocytic leukemia: evidence for a disease specific profile from a comprehensive analysis of 268 mutations
- (2010) T Zenz et al. LEUKEMIA
- TP53 Mutations are infrequent in newly diagnosed chronic lymphocytic leukemia
- (2010) Norafiza Zainuddin et al. LEUKEMIA RESEARCH
- Spliceosome Structure and Function
- (2010) C. L. Will et al. Cold Spring Harbor Perspectives in Biology
- Non-Canonical NF-κB Activation and Abnormal B Cell Accumulation in Mice Expressing Ubiquitin Protein Ligase-Inactive c-IAP2
- (2010) Dietrich B. Conze et al. PLOS BIOLOGY
- Regulation and Function of NF-κB Transcription Factors in the Immune System
- (2009) Sivakumar Vallabhapurapu et al. Annual Review of Immunology
- Monoallelic and biallelic inactivation of TP53 gene in chronic lymphocytic leukemia: selection, impact on survival, and response to DNA damage
- (2009) J. Malcikova et al. BLOOD
- Detailed analysis of p53 pathway defects in fludarabine-refractory chronic lymphocytic leukemia (CLL): dissecting the contribution of 17p deletion, TP53 mutation, p53-p21 dysfunction, and miR34a in a prospective clinical trial
- (2009) T. Zenz et al. BLOOD
- De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience
- (2009) C. S. Tam et al. BLOOD
- The Spliceosome: Design Principles of a Dynamic RNP Machine
- (2009) Markus C. Wahl et al. CELL
- The Prognostic Value of TP53 Mutations in Chronic Lymphocytic Leukemia Is Independent of Del17p13: Implications for Overall Survival and Chemorefractoriness
- (2009) D. Rossi et al. CLINICAL CANCER RESEARCH
- Rituximab, Fludarabine, Cyclophosphamide, and Mitoxantrone: A New, Highly Active Chemoimmunotherapy Regimen for Chronic Lymphocytic Leukemia
- (2009) Francesc Bosch et al. JOURNAL OF CLINICAL ONCOLOGY
- Subcutaneous Alemtuzumab in Fludarabine-Refractory Chronic Lymphocytic Leukemia: Clinical Results and Prognostic Marker Analyses From the CLL2H Study of the German Chronic Lymphocytic Leukemia Study Group
- (2009) Stephan Stilgenbauer et al. JOURNAL OF CLINICAL ONCOLOGY
- p53 expression by immunohistochemistry is an important determinant of survival in patients with chronic lymphocytic leukemia receiving frontline chemo-immunotherapy
- (2009) Ellen J. Schlette et al. LEUKEMIA & LYMPHOMA
- The NF- B subunit Rel A is associated with in vitro survival and clinical disease progression in chronic lymphocytic leukemia and represents a promising therapeutic target
- (2008) S. Hewamana et al. BLOOD
- Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells
- (2008) E. Rosati et al. BLOOD
- Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up
- (2008) T. Zenz et al. BLOOD
- Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute-Working Group 1996 guidelines
- (2008) M. Hallek et al. BLOOD
- The Novel Nuclear Factor- B Inhibitor LC-1 Is Equipotent in Poor Prognostic Subsets of Chronic Lymphocytic Leukemia and Shows Strong Synergy with Fludarabine
- (2008) S. Hewamana et al. CLINICAL CANCER RESEARCH
- The detection of TP53 mutations in chronic lymphocytic leukemia independently predicts rapid disease progression and is highly correlated with a complex aberrant karyotype
- (2008) F Dicker et al. LEUKEMIA
- Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK
- (2008) Brian J Zarnegar et al. NATURE IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search