Defibrotide for the treatment of hepatic veno-occlusive disease in children after hematopoietic stem cell transplantation

Defibrotide for prophylaxis of hepatic veno-occlusive disease in paediatric haemopoietic stem-cell transplantation: an open-label, phase 3, randomised controlled trial

(2012) Selim Corbacioglu et al.   LANCET

A Phase 1 Dose Escalation, Pharmacokinetic, and Pharmacodynamic Evaluation of eIF-4E Antisense Oligonucleotide LY2275796 in Patients with Advanced Cancer

(2011) D. S. Hong et al.   CLINICAL CANCER RESEARCH

Contribution of fibrinolytic tests to the differential diagnosis of veno-occlusive disease complicating pediatric hematopoietic stem cell transplantation

(2011) Maria Teresa Sartori et al.   PEDIATRIC BLOOD & CANCER

Defibrotide for the Treatment of Severe Hepatic Veno-Occlusive Disease and Multiorgan Failure after Stem Cell Transplantation: A Multicenter, Randomized, Dose-Finding Trial

(2010) Paul G. Richardson et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Defibrotide Prevents the Activation of Macrovascular and Microvascular Endothelia Caused by Soluble Factors Released to Blood by Autologous Hematopoietic Stem Cell Transplantation

(2010) Marta Palomo et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Genetic variations in the heparanase gene (HPSE) associate with increased risk of GVHD following allogeneic stem cell transplantation: effect of discrepancy between recipients and donors

(2010) O. Ostrovsky et al.   BLOOD

Safety and efficacy of targeted busulfan therapy in children undergoing myeloablative matched sibling donor BMT for sickle cell disease

(2010) M E McPherson et al.   BONE MARROW TRANSPLANTATION

Melphalan, prednisone, thalidomide and defibrotide in relapsed/refractory multiple myeloma: results of a multicenter phase I/II trial

(2010) A. Palumbo et al.   HAEMATOLOGICA

Pharmacokinetic targeting of intravenous busulfan reduces conditioning regimen related toxicity following allogeneic hematopoietic cell transplantation for acute myelogenous leukemia

(2010) Joseph Pidala et al.   Journal of Hematology & Oncology

Danaparoid as the prophylaxis for hepatic veno-occlusive disease after allogeneic hematopoietic stem cell transplantation in childhood hematological malignancy

(2010) Hirotoshi Sakaguchi et al.   PEDIATRIC BLOOD & CANCER

Hepatic Veno-Occlusive Disease

(2010) Maria Giuseppina Cefalo et al.   PEDIATRIC DRUGS

Hepatic Veno-Occlusive Disease following Stem Cell Transplantation: Incidence, Clinical Course, and Outcome

(2009) Jason A. Coppell et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Safety and efficacy of single-agent lenalidomide in patients with relapsed and refractory multiple myeloma

(2009) P. Richardson et al.   BLOOD

The fibrinolytic mechanism of defibrotide: effect of defibrotide on plasmin activity

(2009) Cinara L Echart et al.   BLOOD COAGULATION & FIBRINOLYSIS

Hepatic veno-occlusive disease in children after hematopoietic stem cell transplantation: incidence, risk factors and outcome

(2009) S H Lee et al.   BONE MARROW TRANSPLANTATION

Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan

(2009) Barbara Cappelli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Preclinical Studies in Support of Defibrotide for the Treatment of Multiple Myeloma and Other Neoplasias

(2009) C. S. Mitsiades et al.   CLINICAL CANCER RESEARCH

Low incidence of hepatic veno-occlusive disease in pediatric patients undergoing hematopoietic stem cell transplantation attributed to a combination of intravenous heparin, oral glutamine, and ursodiol at a single transplant institution

(2009) Sonali Lakshminarayanan et al.   PEDIATRIC TRANSPLANTATION

Angiogenesis alteration by defibrotide: implications for its mechanism of action in severe hepatic veno-occlusive disease

(2008) L. Benimetskaya et al.   BLOOD

Early intervention with antithrombin III therapy to prevent progression of hepatic venoocclusive disease

(2008) Edward Peres et al.   BLOOD COAGULATION & FIBRINOLYSIS

A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation

(2008) L Barkholt et al.   BONE MARROW TRANSPLANTATION

Vascular disorders of the liver

(2008) Laurie D. DeLeve et al.   HEPATOLOGY

Defibrotide in the prevention and treatment of veno-occlusive disease in autologous and allogeneic stem cell transplantation in children

(2008) Amrana Qureshi et al.   PEDIATRIC BLOOD & CANCER