Genomic polymorphisms in sickle cell disease: implications for clinical diversity and treatment

Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls

(2010)   NATURE

Methodological challenges of genome-wide association analysis in Africa

(2010) Yik-Ying Teo et al.   NATURE REVIEWS GENETICS

Association of the MBL2 Gene EXON1 Polymorphism and Vasoocclusive Crisis in Patients with Sickle Cell Anemia

(2009) M.C.V.C. Oliveira et al.   ACTA HAEMATOLOGICA

Effects ofRANTESandMBL2gene polymorphisms in sickle cell disease clinical outcomes: Association of the g.In1.1T>CRANTESvariant with protection against infections

(2009) Omer Placide Dossou-Yovo et al.   AMERICAN JOURNAL OF HEMATOLOGY

Granulocytic sarcoma

(2009)   BLOOD

The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume

(2009) L. Blanc et al.   BLOOD

Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster

(2009) N. Solovieff et al.   BLOOD

Programmed death 1 signaling on chronic myeloid leukemia-specific T cells results in T-cell exhaustion and disease progression

(2009) S. Mumprecht et al.   BLOOD

The pharmacokinetics of codeine and its metabolites in Blacks with sickle cell disease

(2009) Stacy S. Shord et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis

(2009) Abeer M. Al-Subaie et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

rs660 polymorphism in Ro52 (SSA1; TRIM 21) is a marker for age-dependent tolerance induction and efficiency of alloimmunization in sickle cell disease☆

(2009) Zohreh Tatari-Calderone et al.   MOLECULAR IMMUNOLOGY

Finding the missing heritability of complex diseases

(2009) Teri A. Manolio et al.   NATURE

Computation for ChIP-seq and RNA-seq studies

(2009) Shirley Pepke et al.   NATURE METHODS

Detecting gene–gene interactions that underlie human diseases

(2009) Heather J Cordell   NATURE REVIEWS GENETICS

ChIP–seq: advantages and challenges of a maturing technology

(2009) Peter J. Park   NATURE REVIEWS GENETICS

Genetic Variation on Chromosome 6 Influences F Cell Levels in Healthy Individuals of African Descent and HbF Levels in Sickle Cell Patients

(2009) Lisa E. Creary et al.   PLoS One

Epistatic interactions between genetic disorders of hemoglobin can explain why the sickle-cell gene is uncommon in the Mediterranean

(2009) Bridget S. Penman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HLA-G polymorphism influences the susceptibility to HCV infection in sickle cell disease patients

(2009) E. A. A. Cordero et al.   TISSUE ANTIGENS

UGT1A1 promoter polymorphisms and the development of hyperbilirubinemia and gallbladder disease in children with sickle cell anemia

(2008) Shannon L. Carpenter et al.   AMERICAN JOURNAL OF HEMATOLOGY

Association of sickle avascular necrosis with bone morphogenic protein 6

(2008) Pinar Ulug et al.   ANNALS OF HEMATOLOGY

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia

(2008) K. I. Ataga et al.   BLOOD

Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease

(2008) A. E. Ashley-Koch et al.   BLOOD

BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies

(2008) Amanda E. Sedgewick et al.   BLOOD CELLS MOLECULES AND DISEASES

DNA polymorphisms at the BCL11A, HBS1L-MYB, and  -globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

(2008) G. Lettre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sickle Cell Anemia, the First Molecular Disease: Overview of Molecular Etiology, Pathophysiology, and Therapeutic Approaches

(2008) Martin H. Steinberg   TheScientificWorldJOURNAL

Evidence for HLA class II susceptible and protective haplotypes for osteomyelitis in pediatric patients with sickle cell anemia

(2008) K. Al-Ola et al.   TISSUE ANTIGENS

Fetal hemoglobin in sickle cell anemia: Bayesian modeling of genetic associations

(2007) Paola Sebastiani et al.   AMERICAN JOURNAL OF HEMATOLOGY

UGT2B7 promoter variant −840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease

(2007) Deepika S. Darbari et al.   AMERICAN JOURNAL OF HEMATOLOGY

Mutations and polymorphisms in hemoglobin genes and the risk of pulmonary hypertension and death in sickle cell disease

(2007) James G. Taylor et al.   AMERICAN JOURNAL OF HEMATOLOGY