Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer’s disease

Behavioral Improvement after Chronic Administration of Coenzyme Q10 in P301S Transgenic Mice

(2018) Ceyhan Elipenahli et al.   JOURNAL OF ALZHEIMERS DISEASE

Oxidation of KCNB1 potassium channels triggers apoptotic integrin signaling in the brain

(2017) Wei Yu et al.   Cell Death & Disease

Oxidation of KCNB1 Potassium Channels Causes Neurotoxicity and Cognitive Impairment in a Mouse Model of Traumatic Brain Injury

(2016) W. Yu et al.   JOURNAL OF NEUROSCIENCE

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

(2016) Bob Olsson et al.   LANCET NEUROLOGY

ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B-Driven Brainstem Glioma Model

(2016) R. K. Mittapalli et al.   MOLECULAR CANCER THERAPEUTICS

Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer’s disease mouse model

(2016) V Frazzini et al.   Cell Death & Disease

Oxidation of K+Channels in Aging and Neurodegeneration

(2016) Federico Sesti   Aging and Disease

Dasatinib as the salvage therapy for chronic myeloid leukemia with blast crisis and central nervous system involvement: A case report

(2015) SHIUE-WEI LAI et al.   Oncology Letters

Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models

(2014) Scott J. Webster et al.   Frontiers in Genetics

Dasatinib Maintenance Therapy after Allogeneic Hematopoietic Stem Cell Transplantation for an Isolated Central Nervous System Blast Crisis in Chronic Myelogenous Leukemia

(2013) Mitsutaka Nishimoto et al.   ACTA HAEMATOLOGICA

Sunitinib LC–MS/MS Assay in Mouse Plasma and Brain Tissue: Application in CNS Distribution Studies

(2013) Rajneet K. Oberoi et al.   CHROMATOGRAPHIA

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

An evolutionarily conserved mode of modulation of Shaw-like K+ channels

(2012) Diego Cotella et al.   FASEB JOURNAL

Molecular Mechanisms Underlying the Apoptotic Effect of KCNB1 K+Channel Oxidation

(2012) Xilong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer’s disease

(2012) Gunjan Dhawan et al.   Journal of Neuroinflammation

Toxic Role of K+ Channel Oxidation in Mammalian Brain

(2012) D. Cotella et al.   JOURNAL OF NEUROSCIENCE

Isolated central nervous system relapse in patient with blast-crisis chronic myeloid leukemia in durable complete cytogenetic remission on dasatinib treatment: pharmacokinetics and ABL mutation analysis in cerebrospinal fluid

(2012) Hong-Sheng Zhou et al.   LEUKEMIA & LYMPHOMA

Active Efflux of Dasatinib from the Brain Limits Efficacy against Murine Glioblastoma: Broad Implications for the Clinical Use of Molecularly Targeted Agents

(2012) S. Agarwal et al.   MOLECULAR CANCER THERAPEUTICS

P-Glycoprotein Function at the Blood–Brain Barrier: Effects of Age and Gender

(2012) Daniëlle M. E. van Assema et al.   MOLECULAR IMAGING AND BIOLOGY

Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice

(2011) Magali Dumont et al.   FASEB JOURNAL

Oxidative Stress and β-Amyloid Protein in Alzheimer’s Disease

(2011) Zhiyou Cai et al.   NEUROMOLECULAR MEDICINE

Dasatinib induces complete remission in a patient with primary cerebral involvement of B-cell chronic lymphocytic leukemia failing chemotherapy

(2010) G. Russwurm et al.   BLOOD

Excellent response to dasatinib of childhood Philadelphia positive intracranial acute lymphoblastic leukaemia tumours

(2010) Vivek A. Bhadri et al.   BRITISH JOURNAL OF HAEMATOLOGY

GFAP and S100B are biomarkers of traumatic brain injury: An observational cohort study

(2010) P. E. Vos et al.   NEUROLOGY

Brain Accumulation of Dasatinib Is Restricted by P-Glycoprotein (ABCB1) and Breast Cancer Resistance Protein (ABCG2) and Can Be Enhanced by Elacridar Treatment

(2009) J. S. Lagas et al.   CLINICAL CANCER RESEARCH

P-glycoprotein and Breast Cancer Resistance Protein Influence Brain Distribution of Dasatinib

(2009) Y. Chen et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Dasatinib in the management of lymphoid blast crisis of Philadelphia-positive chronic myeloid leukemia with multiple extra-medullary and intracranial localizations

(2009) Giuliana Alimena et al.   LEUKEMIA RESEARCH

Oxidation of a potassium channel causes progressive sensory function loss during aging

(2009) Shi-Qing Cai et al.   NATURE NEUROSCIENCE

Dasatinib crosses the blood-brain barrier and is an efficient therapy for central nervous system Philadelphia chromosome-positive leukemia

(2008) K. Porkka et al.   BLOOD