Reprogramming the fate of human glioma cells to impede brain tumor development

Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-κB

(2014) A Tchoghandjian et al.   CELL DEATH AND DIFFERENTIATION

In Vivo Direct Reprogramming of Reactive Glial Cells into Functional Neurons after Brain Injury and in an Alzheimer’s Disease Model

(2013) Ziyuan Guo et al.   Cell Stem Cell

BMP Signaling Induces Astrocytic Differentiation of Clinically Derived Oligodendroglioma Propagating Cells

(2013) Maya Srikanth et al.   MOLECULAR CANCER RESEARCH

In vivo reprogramming of astrocytes to neuroblasts in the adult brain

(2013) Wenze Niu et al.   NATURE CELL BIOLOGY

Generation of induced neurons via direct conversion in vivo

(2013) O. Torper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells

(2013) D. Rohle et al.   SCIENCE

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

Reprogramming of Pericyte-Derived Cells of the Adult Human Brain into Induced Neuronal Cells

(2012) Marisa Karow et al.   Cell Stem Cell

Direct reprogramming of human astrocytes into neural stem cells and neurons

(2012) Stefania Corti et al.   EXPERIMENTAL CELL RESEARCH

Cell death and neuronal differentiation of glioblastoma stem-like cells induced by neurogenic transcription factors

(2012) Pierre-Olivier Guichet et al.   GLIA

Recent advances in the molecular understanding of glioblastoma

(2012) Fonnet E. Bleeker et al.   JOURNAL OF NEURO-ONCOLOGY

SoxC Transcription Factors Are Required for Neuronal Differentiation in Adult Hippocampal Neurogenesis

(2012) L. Mu et al.   JOURNAL OF NEUROSCIENCE

Neuronal Transcription Factors Induce Conversion of Human Glioma Cells to Neurons and Inhibit Tumorigenesis

(2012) Junli Zhao et al.   PLoS One

Glioma Development: Where Did It All Go Wrong?

(2011) Kumar Sukhdeo et al.   CELL

Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons

(2011) Esther Y. Son et al.   Cell Stem Cell

Activation of Postnatal Neural Stem Cells Requires Nuclear Receptor TLX

(2011) W. Niu et al.   JOURNAL OF NEUROSCIENCE

MicroRNA-146a Inhibits Glioma Development by Targeting Notch1

(2011) J. Mei et al.   MOLECULAR AND CELLULAR BIOLOGY

Generation of subtype-specific neurons from postnatal astroglia of the mouse cerebral cortex

(2011) Christophe Heinrich et al.   Nature Protocols

Efficient Conversion of Astrocytes to Functional Midbrain Dopaminergic Neurons Using a Single Polycistronic Vector

(2011) Russell C. Addis et al.   PLoS One

microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

(2010) Fadila Guessous et al.   CELL CYCLE

Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells

(2010) B. Campos et al.   CLINICAL CANCER RESEARCH

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Directing Astroglia from the Cerebral Cortex into Subtype Specific Functional Neurons

(2010) Christophe Heinrich et al.   PLOS BIOLOGY

Sox11 Prevents Tumorigenesis of Glioma-Initiating Cells by Inducing Neuronal Differentiation

(2009) T. Hide et al.   CANCER RESEARCH

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

Doublecortin induces mitotic microtubule catastrophe and inhibits glioma cell invasion

(2008) Manoranjan Santra et al.   JOURNAL OF NEUROCHEMISTRY