Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells

A switch in the source of ATP production and a loss in capacity to perform glycolysis are hallmarks of hepatocyte failure in advance liver disease

(2014) Taichiro Nishikawa et al.   JOURNAL OF HEPATOLOGY

Metabolic shifts toward glutamine regulate tumor growth, invasion and bioenergetics in ovarian cancer

(2014) L. Yang et al.   Molecular Systems Biology

A light-activated NO donor attenuates anchorage independent growth of cancer cells: Important role of a cross talk between NO and other reactive oxygen species

(2013) Suvajit Sen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A detergent-free strategy for the reconstitution of active enzyme complexes from native biological membranes into nanoscale discs

(2013) Ashley R Long et al.   BMC BIOTECHNOLOGY

Nitric Oxide Production Upregulates Wnt/ -Catenin Signaling by Inhibiting Dickkopf-1

(2013) Q. Du et al.   CANCER RESEARCH

Targeting SOD1 reduces experimental non–small-cell lung cancer

(2013) Andrea Glasauer et al.   JOURNAL OF CLINICAL INVESTIGATION

Understanding Metabolic Regulation and Its Influence on Cell Physiology

(2013) Christian M. Metallo et al.   MOLECULAR CELL

Rare Genomic Structural Variants in Complex Disease: Lessons from the Replication of Associations with Obesity

(2013) Robin G. Walters et al.   PLoS One

Long-Term Nitric Oxide Exposure Enhances Lung Cancer Cell Migration

(2013) Arpasinee Sanuphan et al.   Biomed Research International

Nitric oxide-releasing prodrug triggers cancer cell death through deregulation of cellular redox balance

(2013) Anna E. Maciag et al.   Redox Biology

Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration

(2012) Christine A. Caneba et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Arginine de novo and nitric oxide production in disease states

(2012) Yvette C. Luiking et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Depletion ofL-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes

(2012) Rósula García-Navas et al.   Autophagy

Mitochondrial dysfunction promotes cell migration via reactive oxygen species-enhanced β5-integrin expression in human gastric cancer SC-M1 cells

(2012) Wen-Yi Hung et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Negative argininosuccinate synthetase expression in melanoma tumours may predict clinical benefit from arginine-depleting therapy with pegylated arginine deiminase

(2012) L G Feun et al.   BRITISH JOURNAL OF CANCER

Metabolic Regulation of Epigenetics

(2012) Chao Lu et al.   Cell Metabolism

Nitric Oxide Produced Endogenously Is Responsible for Hypoxia-Induced HIF-1α Stabilization in Colon Carcinoma Cells

(2012) Rajdeep Chowdhury et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Conceptual Framework for Cutting the Pancreatic Cancer Fuel Supply

(2012) A. Le et al.   CLINICAL CANCER RESEARCH

Mitochondrial-associated nitric oxide synthase activity inhibits cytochrome c oxidase: Implications for breast Cancer

(2012) Suvajit Sen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Overexpression of Romo1 Promotes Production of Reactive Oxygen Species and Invasiveness of Hepatic Tumor Cells

(2012) Jin Sil Chung et al.   GASTROENTEROLOGY

Part II. Mitochondrial mutational status of high nitric oxide adapted cell line BT-20 (BT-20-HNO) as it relates to human primary breast tumors

(2012) H. De Vitto et al.   TUMOR BIOLOGY

Part III. Molecular changes induced by high nitric oxide adaptation in human breast cancer cell line BT-20 (BT-20-HNO): a switch from aerobic to anaerobic metabolism

(2012) H. De Vitto et al.   TUMOR BIOLOGY

Metabolomics for mitochondrial and cancer studies

(2011) Deepak Nagrath et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mitochondrial targeted catalase suppresses invasive breast cancer in mice

(2011) Jorming Goh et al.   BMC CANCER

Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetase

(2011) M P Kelly et al.   BRITISH JOURNAL OF CANCER

Nitric Oxide and Calcium Participate in the Fine Regulation of Mitochondrial Biogenesis in Follicular Thyroid Carcinoma Cells

(2011) Soazig Le Pennec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of nitric oxide synthase-3 overexpression on post-translational modifications and cell survival in HepG2 cells

(2011) P. Aguilar-Melero et al.   Journal of Proteomics

A randomised phase II study of pegylated arginine deiminase (ADI-PEG 20) in Asian advanced hepatocellular carcinoma patients

(2010) T-S Yang et al.   BRITISH JOURNAL OF CANCER

Arginine Deiminase as a Novel Therapy for Prostate Cancer Induces Autophagy and Caspase-Independent Apoptosis

(2009) R. H. Kim et al.   CANCER RESEARCH

Epigenetic silencing of argininosuccinate synthetase confers resistance to platinum-induced cell death but collateral sensitivity to arginine auxotrophy in ovarian cancer

(2009) Linda J. Nicholson et al.   INTERNATIONAL JOURNAL OF CANCER

PGC-1-Related Coactivator Modulates Mitochondrial-Nuclear Crosstalk through Endogenous Nitric Oxide in a Cellular Model of Oncocytic Thyroid Tumours

(2009) Mahatsangy Raharijaona et al.   PLoS One

Arginine deiminase, a potential anti-tumor drug

(2008) Ye Ni et al.   CANCER LETTERS

Oxidative Stress Is Inherent in Prostate Cancer Cells and Is Required for Aggressive Phenotype

(2008) B. Kumar et al.   CANCER RESEARCH

A Gene Signature Predicting for Survival in Suboptimally Debulked Patients with Ovarian Cancer

(2008) T. Bonome et al.   CANCER RESEARCH