HKH40A downregulates GRP78/BiP expression in cancer cells

Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78

(2013) S Martin et al.   BRITISH JOURNAL OF CANCER

Modulation of ER stress and apoptosis by endoplasmic reticulum calcium leak via translocon during unfolded protein response: involvement of GRP78

(2013) Mehdi Hammadi et al.   FASEB JOURNAL

Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions

(2012) Susanne A.I. Seidel et al.   METHODS

The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies

(2012) B Luo et al.   ONCOGENE

Molecular Interaction Studies Using Microscale Thermophoresis

(2011) Moran Jerabek-Willemsen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Glucose regulated protein 78 (GRP78) is overexpressed in colorectal carcinoma and regulates colorectal carcinoma cell growth and apoptosis

(2010) Xiaoming Xing et al.   ACTA HISTOCHEMICA

The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78

(2010) G. Roue et al.   BLOOD

Targeting plasma membrane GRP78 for cancer growth inhibition

(2010) Steve Schwarze et al.   CANCER BIOLOGY & THERAPY

Unfolded protein response activation contributes to chemoresistance in hepatocellular carcinoma

(2010) Feras Y. Al-Rawashdeh et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling

(2010) Meng-Ju Wu et al.   Molecular Cancer

Targeting GRP78 to enhance melanoma cell death

(2010) Shaun Martin et al.   Pigment Cell & Melanoma Research

Protein-binding assays in biological liquids using microscale thermophoresis

(2010) Christoph J. Wienken et al.   Nature Communications

GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib

(2009) J. Kern et al.   BLOOD

Activation and clinical significance of the unfolded protein response in breast cancer

(2009) P Scriven et al.   BRITISH JOURNAL OF CANCER

Upregulation of GRP78 and GRP94 and Its Function in Chemotherapy Resistance to VP-16 in Human Lung Cancer Cell Line SK-MES-1

(2009) Lichuan Zhang et al.   CANCER INVESTIGATION

The Thioxotriazole Copper(II) Complex A0 Induces Endoplasmic Reticulum Stress and Paraptotic Death in Human Cancer Cells

(2009) Saverio Tardito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response

(2009) Jiao Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition

(2009) Ziqiu Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis

(2009) P. Baumeister et al.   MOLECULAR CANCER THERAPEUTICS

Expression and clinical significance of Glucose Regulated Proteins GRP78 (BiP) and GRP94 (GP96) in human adenocarcinomas of the esophagus

(2008) Rupert Langer et al.   BMC CANCER

Growth inhibition of hepatocellular carcinoma cells in vitro and in vivo by the 8-methoxy analog of WMC79

(2008) Teresa Kosakowska-Cholody et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Overexpression of GRP78 and GRP94 are markers for aggressive behavior and poor prognosis in gastric carcinomas

(2008) Hua-chuan Zheng et al.   HUMAN PATHOLOGY