The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer

Delivery and therapeutic potential of human granzyme B

(2015) Florian C. Kurschus et al.   IMMUNOLOGICAL REVIEWS

Androgen Receptor-Independent Function of FoxA1 in Prostate Cancer Metastasis

(2013) H.-J. Jin et al.   CANCER RESEARCH

The PSA−/lo Prostate Cancer Cell Population Harbors Self-Renewing Long-Term Tumor-Propagating Cells that Resist Castration

(2012) Jichao Qin et al.   Cell Stem Cell

Protease-Activated Drug Development

(2012) Ki Young Choi et al.   Theranostics

CCAAT/Enhancer-binding Protein δ Mediates Tumor Necrosis Factor α-induced Aurora Kinase C Transcription and Promotes Genomic Instability

(2011) Sin-Rong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FBXW7 influences murine intestinal homeostasis and cancer, targeting Notch, Jun, and DEK for degradation

(2011) Roya Babaei-Jadidi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inhibition of the Acetyltransferases p300 and CBP Reveals a Targetable Function for p300 in the Survival and Invasion Pathways of Prostate Cancer Cell Lines

(2011) F. R. Santer et al.   MOLECULAR CANCER THERAPEUTICS

Androgen receptor footprint on the way to prostate cancer progression

(2011) Myles C. Hodgson et al.   WORLD JOURNAL OF UROLOGY

Transcriptional up-regulation of SOD1 by CEBPD: A potential target for cisplatin resistant human urothelial carcinoma cells

(2010) Tzyh-Chyuan Hour et al.   BIOCHEMICAL PHARMACOLOGY

CEBPD Reverses RB/E2F1-Mediated Gene Repression and Participates in HMDB-Induced Apoptosis of Cancer Cells

(2010) Y.-C. Pan et al.   CLINICAL CANCER RESEARCH

The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis

(2010) Kuppusamy Balamurugan et al.   EMBO JOURNAL

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression

(2010) Ankur Sharma et al.   JOURNAL OF CLINICAL INVESTIGATION

Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun

(2010) Joerg D Hoeck et al.   NATURE NEUROSCIENCE

A Novel Antitumor Prodrug Platform Designed to Be Cleaved by the Endoprotease Legumain

(2009) Liron Stern et al.   BIOCONJUGATE CHEMISTRY

Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

(2009) J. Thiery et al.   BLOOD

Role of Cyclic AMP Response Element-Binding Protein in Insulin-like Growth Factor-I Receptor Up-regulation by Sex Steroids in Prostate Cancer Cells

(2009) M. Genua et al.   CANCER RESEARCH

Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth

(2008) R. B. Montgomery et al.   CANCER RESEARCH

Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry

(2008) Dominique Trudel et al.   HUMAN PATHOLOGY

Epigenetic Silencing of CCAAT/Enhancer-binding Protein δ Activity by YY1/Polycomb Group/DNA Methyltransferase Complex

(2008) Chiung-Yuan Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sumoylation of LAP1 is involved in the HDAC4-mediated repression of COX-2 transcription

(2008) Wen-Ling Wang et al.   NUCLEIC ACIDS RESEARCH