Inhibition of phosphodiesterase 5 reduces bone mass by suppression of canonical Wnt signaling

Dehydroascorbic acid taken up by glucose transporters stimulates estradiol production through inhibition of JNK/c-Jun/AP1 signaling in JAR cells

(2014) Yongjie Wang et al.   MOLECULAR HUMAN REPRODUCTION

WNT7B Promotes Bone Formation in part through mTORC1

(2014) Jianquan Chen et al.   PLoS Genetics

Variation in the Kozak sequence of WNT16 results in an increased translation and is associated with osteoporosis related parameters

(2013) Gretl Hendrickx et al.   BONE

Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/ -Catenin Signaling

(2013) N. Li et al.   MOLECULAR CANCER THERAPEUTICS

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches

(2013) Ernesto Canalis   Nature Reviews Endocrinology

Ascorbic Acid Uptaken by Sodium-Dependent Vitamin C Transporter 2 Induces βhCG Expression through Sp1 and TFAP2A Transcription Factors in Human Choriocarcinoma Cells

(2012) Lihua Chen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Secreted and Transmembrane Wnt Inhibitors and Activators

(2012) C.-M. Cruciat et al.   Cold Spring Harbor Perspectives in Biology

Alternative Wnt Pathways and Receptors

(2012) R. van Amerongen   Cold Spring Harbor Perspectives in Biology

Tadalafil as monotherapy and in combination regimens for the treatment of pulmonary arterial hypertension

(2012) Dioma U. Udeoji et al.   Therapeutic Advances in Respiratory Disease

Inhibition of PDE5 by Sulindac Sulfide Selectively Induces Apoptosis and Attenuates Oncogenic Wnt/ -Catenin-Mediated Transcription in Human Breast Tumor Cells

(2011) H. N. Tinsley et al.   Cancer Prevention Research

Genetic Ablation of cGMP-Dependent Protein Kinase Type I Causes Liver Inflammation and Fasting Hyperglycemia

(2011) S. Z. Lutz et al.   DIABETES

Colon Tumor Cell Growth-Inhibitory Activity of Sulindac Sulfide and Other Nonsteroidal Anti-Inflammatory Drugs Is Associated with Phosphodiesterase 5 Inhibition

(2010) H. N. Tinsley et al.   Cancer Prevention Research

An update on new oral PDE5 inhibitors for the treatment of erectile dysfunction

(2010) Victor Palit et al.   Nature Reviews Urology

cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action

(2010) S. H. Francis et al.   PHARMACOLOGICAL REVIEWS

A nonsense mutation in cGMP-dependent type II protein kinase (PRKG2) causes dwarfism in American Angus cattle

(2009) J. E. Koltes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sfrp Controls Apicobasal Polarity and Oriented Cell Division in Developing Gut Epithelium

(2009) Makoto Matsuyama et al.   PLoS Genetics

Rac1 Activation Controls Nuclear Localization of β-catenin during Canonical Wnt Signaling

(2008) Ximei Wu et al.   CELL

Phosphorylation of GSK-3β by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes

(2008) Yosuke Kawasaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE