NMDA receptor-mediated excitotoxicity depends on the coactivation of synaptic and extrasynaptic receptors

Synaptic NMDA Receptors Mediate Hypoxic Excitotoxic Death

(2012) C. M. Wroge et al.   JOURNAL OF NEUROSCIENCE

Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

(2011) A. E. Barry et al.   JOURNAL OF NEUROSCIENCE

Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function

(2011) Clare M. Gladding et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

NMDA receptors: Recent insights and clinical correlations

(2011) E. E. Benarroch   NEUROLOGY

Calcium, ischemia and excitotoxicity

(2010) Kinga Szydlowska et al.   CELL CALCIUM

Memantine Preferentially Blocks Extrasynaptic over Synaptic NMDA Receptor Currents in Hippocampal Autapses

(2010) P. Xia et al.   JOURNAL OF NEUROSCIENCE

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Memantine

(2009) Kate McKeage   CNS DRUGS

Hippocampal NMDA receptor subunits differentially regulate fear memory formation and neuronal signal propagation

(2009) Can Gao et al.   HIPPOCAMPUS

Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity

(2009) Linda K. Friedman et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

N-methyl-D-aspartate-stimulated ERK1/2 signaling and the transcriptional up-regulation of plasticity-related genes are developmentally regulated following in vitro neuronal maturation

(2009) Xianju Zhou et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Reverse glial glutamate uptake triggers neuronal cell death through extrasynaptic NMDA receptor activation

(2009) E. Gouix et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A quantitative method to assess extrasynaptic NMDA receptor function in the protective effect of synaptic activity against neurotoxicity

(2008) C Peter Bengtson et al.   BMC NEUROSCIENCE

Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

(2008) F. Léveillé et al.   FASEB JOURNAL

Recruiting Extrasynaptic NMDA Receptors Augments Synaptic Signaling

(2007) Alexander Z. Harris et al.   JOURNAL OF NEUROPHYSIOLOGY