Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson’s disease
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Title
Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson’s disease
Authors
Keywords
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Journal
Cell Death & Disease
Volume 4, Issue 1, Pages e467-e467
Publisher
Springer Nature
Online
2013-01-17
DOI
10.1038/cddis.2012.205
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- Drosophila Parkin requires PINK1 for mitochondrial translocation and ubiquitinates Mitofusin
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- Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin
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- Mitochondrial fusion, fission and autophagy as a quality control axis: The bioenergetic view
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- Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
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- The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
- (2008) H. Deng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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