Mutual regulation between DNA-PKcs and snail1 leads to increased genomic instability and aggressive tumor characteristics

DNA-PKCS binding to p53 on the p21WAF1/CIP1 promoter blocks transcription resulting in cell death

(2015) Richard Hill et al.   Oncotarget

DNA-PKcs-mediated stabilization of p53 by JNK2 is involved in arsenite-induced DNA damage and apoptosis in human embryo lung fibroblast cells

(2012) Yuan Li et al.   TOXICOLOGY LETTERS

Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair

(2011) Shichuan Zhang et al.   JOURNAL OF CELL BIOLOGY

Orphan Receptor TR3 Enhances p53 Transactivation and Represses DNA Double-Strand Break Repair in Hepatoma Cells under Ionizing Radiation

(2011) Bi-xing Zhao et al.   MOLECULAR ENDOCRINOLOGY

Radiosensitivity profiles from a panel of ovarian cancer cell lines exhibiting genetic alterations in p53 and disparate DNA-dependent protein kinase activities

(2010) Langland   ONCOLOGY REPORTS

A Role of DNA-PK for the Metabolic Gene Regulation in Response to Insulin

(2009) Roger H.F. Wong et al.   CELL

Inhibition of 11β–hydroxysteroid dehydrogenase type II selectively blocks the tumor COX-2 pathway and suppresses colon carcinogenesis in mice and humans

(2009) Ming-Zhi Zhang et al.   JOURNAL OF CLINICAL INVESTIGATION

Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells

(2009) Nawneet K. Kurrey et al.   STEM CELLS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

The endless tale of non-homologous end-joining

(2008) Eric Weterings et al.   CELL RESEARCH