Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis

SMC6 is an essential gene in mice, but a hypomorphic mutant in the ATPase domain has a mild phenotype with a range of subtle abnormalities

(2013) Limei Ju et al.   DNA REPAIR

Molecular control of rodent spermatogenesis

(2012) Sabrina Z. Jan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

During Replication Stress, Non-Smc Element 5 (Nse5) Is Required for Smc5/6 Protein Complex Functionality at Stalled Forks

(2012) Denise E. Bustard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Meiotic DNA joint molecule resolution depends on Nse5-Nse6 of the Smc5-Smc6 holocomplex

(2012) S. Wehrkamp-Richter et al.   NUCLEIC ACIDS RESEARCH

The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

(2012) Frank Sleutels et al.   Epigenetics & Chromatin

The Smc complexes in DNA damage response

(2012) Nan Wu et al.   Cell and Bioscience

Double-Strand Breaks in Heterochromatin Move Outside of a Dynamic HP1a Domain to Complete Recombinational Repair

(2011) Irene Chiolo et al.   CELL

Chromosome length influences replication-induced topological stress

(2011) Andreas Kegel et al.   NATURE

The Smc5–Smc6 Complex Is Required to Remove Chromosome Junctions in Meiosis

(2011) Sarah Farmer et al.   PLoS One

RAD21 Cooperates with Pluripotency Transcription Factors in the Maintenance of Embryonic Stem Cell Identity

(2011) Anja Nitzsche et al.   PLoS One

Cohesin phosphorylation and mobility of SMC1 at ionizing radiation-induced DNA double-strand breaks in human cells

(2010) Christina Bauerschmidt et al.   EXPERIMENTAL CELL RESEARCH

Saccharomyces cerevisiaeEsc2p Interacts with Sir2p through a Small Ubiquitin-like Modifier (SUMO)-binding Motif and Regulates Transcriptionally Silent Chromatin in a Locus-dependent Manner

(2010) Qun Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Condensin and cohesin complexity: the expanding repertoire of functions

(2010) Andrew J. Wood et al.   NATURE REVIEWS GENETICS

RNAi and heterochromatin repress centromeric meiotic recombination

(2010) C. Ellermeier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell type specificity of chromatin organization mediated by CTCF and cohesin

(2010) Chunhui Hou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The pluripotency factor LIN28 marks undifferentiated spermatogonia in mouse

(2009) Ke Zheng et al.   BMC DEVELOPMENTAL BIOLOGY

Condensin: Architect of mitotic chromosomes

(2009) Damien F. Hudson et al.   CHROMOSOME RESEARCH

The unnamed complex: what do we know about Smc5-Smc6?

(2009) Giacomo De Piccoli et al.   CHROMOSOME RESEARCH

The Yin and Yang of the MMS21–SMC5/6 SUMO ligase complex in homologous recombination

(2009) Patrick Ryan Potts   DNA REPAIR

Smc5/6 maintains stalled replication forks in a recombination-competent conformation

(2009) Anja Irmisch et al.   EMBO JOURNAL

Cohesins Functionally Associate with CTCF on Mammalian Chromosome Arms

(2008) Vania Parelho et al.   CELL

The cohesin complex and its roles in chromosome biology

(2008) J.-M. Peters et al.   GENES & DEVELOPMENT

Cohesin mediates transcriptional insulation by CCCTC-binding factor

(2008) Kerstin S. Wendt et al.   NATURE

CTCF physically links cohesin to chromatin

(2008) E. D. Rubio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA