Regulation of the tumor suppressor PTEN by SUMO

SUMO1 modification of PTEN regulates tumorigenesis by controlling its association with the plasma membrane

(2012) Jian Huang et al.   Nature Communications

Human Pathogens and the Host Cell SUMOylation System

(2011) P. Wimmer et al.   JOURNAL OF VIROLOGY

In vivo analysis of protein sumoylation induced by a viral protein: Detection of HCMV pp71-induced Daxx sumoylation

(2011) Jiwon Hwang et al.   METHODS

Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice

(2010) M. Moussavi et al.   CANCER RESEARCH

SIRT1 stabilizes PML promoting its sumoylation

(2010) M Campagna et al.   CELL DEATH AND DIFFERENTIATION

Adenovirus E1B 55-Kilodalton Protein Is a p53-SUMO1 E3 Ligase That Represses p53 and Stimulates Its Nuclear Export through Interactions with Promyelocytic Leukemia Nuclear Bodies

(2010) M. A. Pennella et al.   JOURNAL OF VIROLOGY

Autophagy Is an Essential Component of Drosophila Immunity against Vesicular Stomatitis Virus

(2009) Spencer Shelly et al.   IMMUNITY

Kaposi's Sarcoma-associated Herpesvirus (KSHV) Encodes a SUMO E3 ligase That Is SIM-dependent and SUMO-2/3-specific

(2009) Pei-Ching Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Kaposi's Sarcoma-Associated Herpesvirus Protein LANA2 Disrupts PML Oncogenic Domains and Inhibits PML-Mediated Transcriptional Repression of the Survivin Gene

(2009) L. Marcos-Villar et al.   JOURNAL OF VIROLOGY

Principles of ubiquitin and SUMO modifications in DNA repair

(2009) Steven Bergink et al.   NATURE

Arsenic trioxide stimulates SUMO-2/3 modification leading to RNF4-dependent proteolytic targeting of PML

(2008) Stefan R. Weisshaar et al.   FEBS LETTERS

Virus Infection Triggers SUMOylation of IRF3 and IRF7, Leading to the Negative Regulation of Type I Interferon Gene Expression

(2008) Toru Kubota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin-Proteasome System Is a Key Component of the SUMO-2/3 Cycle

(2008) Joost Schimmel et al.   MOLECULAR & CELLULAR PROTEOMICS

Mechanism and Consequences for Paralog-Specific Sumoylation of Ubiquitin-Specific Protease 25

(2008) Erik Meulmeester et al.   MOLECULAR CELL

The deubiquitinylation and localization of PTEN are regulated by a HAUSP–PML network

(2008) Min Sup Song et al.   NATURE

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

A phosphorylation-dependent intramolecular interaction regulates the membrane association and activity of the tumor suppressor PTEN

(2008) M. Rahdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy

(2008) Pauline Chugh et al.   Retrovirology