NOXA as critical mediator for drug combinations in polychemotherapy

Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice

(2012) Ines Höfig et al.   Cell Communication and Signaling

Optimized anti-tumor effects of anthracyclines plus Vinca alkaloids using a novel, mechanism-based application schedule

(2011) H. Ehrhardt et al.   BLOOD

Important Role of Caspase-8 for Chemosensitivity of ALL Cells

(2011) H. Ehrhardt et al.   CLINICAL CANCER RESEARCH

Different contribution of BH3-only proteins and caspases to doxorubicin-induced apoptosis in p53-deficient leukemia cells

(2010) Nuria López-Royuela et al.   BIOCHEMICAL PHARMACOLOGY

Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways

(2010) L Zhang et al.   CELL DEATH AND DIFFERENTIATION

ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia

(2010) S H Tonino et al.   ONCOGENE

An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs

(2010) C Sheridan et al.   ONCOGENE

Therapeutic potential of proapoptotic molecule Noxa in the selective elimination of tumor cells

(2009) Saori Suzuki et al.   CANCER SCIENCE

Noxa: at the tip of the balance between life and death

(2009) C Ploner et al.   ONCOGENE

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Betulinic acid: A natural product with anticancer activity

(2008) Simone Fulda   MOLECULAR NUTRITION & FOOD RESEARCH

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY