Intrinsic caspase-8 activation mediates sensitization of erlotinib-resistant tumor cells to erlotinib/cell-cycle inhibitors combination treatment

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

(2012) Michael J. Lee et al.   CELL

The PIDDosome, DNA-damage-induced apoptosis and beyond

(2011) S Janssens et al.   CELL DEATH AND DIFFERENTIATION

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

(2011) Maria Feoktistova et al.   MOLECULAR CELL

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

(2011) Tencho Tenev et al.   MOLECULAR CELL

Treatment of HER2-positive breast cancer: current status and future perspectives

(2011) Carlos L. Arteaga et al.   Nature Reviews Clinical Oncology

Cetuximab-Associated Elongation of the Eyelashes

(2010) Philip R. Cohen et al.   AMERICAN JOURNAL OF CLINICAL DERMATOLOGY

Bcl-2 proteins and mitochondria—Specificity in membrane targeting for death

(2010) Jennefer Lindsay et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Synergistic Antitumor Activity of Sorafenib in Combination with Epidermal Growth Factor Receptor Inhibitors in Colorectal and Lung Cancer Cells

(2010) E. Martinelli et al.   CLINICAL CANCER RESEARCH

Focus on histone variant H2AX: To be or not to be

(2010) Jingsong Yuan et al.   FEBS LETTERS

Synergistic interaction between trastuzumab and EGFR/HER-2 tyrosine kinase inhibitors in HER-2 positive breast cancer cells

(2010) Norma O’Donovan et al.   INVESTIGATIONAL NEW DRUGS

New strategies to overcome limitations of reversible EGFR tyrosine kinase inhibitor therapy in non-small cell lung cancer

(2010) Robert C. Doebele et al.   LUNG CANCER

EGFR signaling in breast cancer: Bad to the bone

(2010) John Foley et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Efficacy and safety of erlotinib in patients with locally advanced or metastatic breast cancer

(2008) Maura N. Dickler et al.   BREAST CANCER RESEARCH AND TREATMENT

MCF-7 breast carcinoma cells do not express caspase-3

(2008) Reiner U. Jänicke   BREAST CANCER RESEARCH AND TREATMENT

TNF-α Induces Two Distinct Caspase-8 Activation Pathways

(2008) Lai Wang et al.   CELL

Identification of a Molecular Signaling Network that Regulates a Cellular Necrotic Cell Death Pathway

(2008) Junichi Hitomi et al.   CELL

Synergistic Inhibition of ErbB Signaling by Combined Treatment with Seliciclib and ErbB-Targeting Agents

(2008) I. N. Fleming et al.   CLINICAL CANCER RESEARCH

Modulation of Cellular Apoptosis with Apoptotic Protease-Activating Factor 1 (Apaf-1) Inhibitors

(2008) L. Mondragón et al.   JOURNAL OF MEDICINAL CHEMISTRY