Inhibition of Rac1 signaling by lovastatin protects against anthracycline-induced cardiac toxicity

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

(2014) Tomáš Šimůnek et al.   Pharmacological Reports

Modulation of the Rho/ROCK Pathway in Heart and Lung after Thorax Irradiation Reveals Targets to Improve Normal Tissue Toxicity

(2012) Virginie Monceau et al.   CURRENT DRUG TARGETS

Pleiotropic Effects of Statins

(2010) Qian Zhou et al.   CIRCULATION JOURNAL

Statins inhibit aminoglycoside accumulation and cytotoxicity to renal proximal tubule cells

(2009) Daniel J. Antoine et al.   BIOCHEMICAL PHARMACOLOGY

Anthracycline Degradation in Cardiomyocytes: A Journey to Oxidative Survival

(2009) Pierantonio Menna et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Importance of Rac1 Signaling Pathway Inhibition in the Pleiotropic Effects of HMG-CoA Reductase Inhibitors

(2009) Mamunur Rashid et al.   CIRCULATION JOURNAL

Targeting the Mevalonate Pathway for Improved Anticancer Therapy

(2009) G. Fritz   CURRENT CANCER DRUG TARGETS

Topoisomerase II -dependent and -independent apoptotic effects of dexrazoxane and doxorubicin

(2009) T. Yan et al.   MOLECULAR CANCER THERAPEUTICS

Statins and cardioprotection — More than just lipid lowering?

(2009) Andrew Ludman et al.   PHARMACOLOGY & THERAPEUTICS

Lovastatin attenuates ionizing radiation-induced normal tissue damage in vivo

(2009) Christian Ostrau et al.   RADIOTHERAPY AND ONCOLOGY

The Nuclear Import of the Small GTPase Rac1 is Mediated by the Direct Interaction with Karyopherin α2

(2009) Kirstin Sandrock et al.   TRAFFIC

Anthracycline Cardiotoxicity: From Bench to Bedside

(2008) Luca Gianni et al.   JOURNAL OF CLINICAL ONCOLOGY

A Bacterial Cytotoxin Identifies the RhoA Exchange Factor Net1 as a Key Effector in the Response to DNA Damage

(2008) Lina Guerra et al.   PLoS One

Pleiotropic effects of statin therapy: molecular mechanisms and clinical results

(2008) Chao-Yung Wang et al.   TRENDS IN MOLECULAR MEDICINE

Reversal of chemoresistance and enhancement of apoptosis by statins through down-regulation of the NF-κB pathway

(2007) Kwang Seok Ahn et al.   BIOCHEMICAL PHARMACOLOGY

Lovastatin protects human endothelial cells from the genotoxic and cytotoxic effects of the anticancer drugs doxorubicin and etoposide

(2006) J Damrot et al.   BRITISH JOURNAL OF PHARMACOLOGY