4.1 Review

Impact of steroid hormone signals on Drosophila cell cycle during development

Journal

CELL DIVISION
Volume 4, Issue -, Pages -

Publisher

BIOMED CENTRAL LTD
DOI: 10.1186/1747-1028-4-3

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Funding

  1. Australian National Health and Medical Research Council (NHMRC)
  2. Cancer Council of Victoria (CCV)

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Metamorphosis of Drosophila involves proliferation, differentiation and death of larval tissues in order to form the adult fly. The major steroid hormone implicated in the larval-pupal transition and adult tissue modelling is ecdysone. Previous reviews have draw together studies connecting ecdysone signaling to the processes of apoptosis and differentiation. Here we discuss those reports connecting the ecdysone pulse to developmentally regulated cell cycle progression.

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