Prevention of DNA re-replication in eukaryotic cells

Replication licensing and the DNA damage checkpoint

(2010) Jeanette Gowen Cook   Frontiers in Bioscience-Landmark

Dynamics of Pre-replicative Complex Assembly

(2010) Vasiliki Tsakraklides et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Mutagenesis Studies of the C-terminal Region of Licensing Factor Cdt1 Enable the Identification of Key Residues for Binding to Replicative Helicase Mcm Proteins

(2010) JunGoo Jee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization and Structure Determination of the Cdt1 Binding Domain of Human Minichromosome Maintenance (Mcm) 6

(2010) Zhun Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin

(2010) Benoit Miotto et al.   MOLECULAR CELL

Factors Affecting the Diversity of DNA Replication Licensing Control in Eukaryotes

(2009) Lucy S. Drury et al.   CURRENT BIOLOGY

Acetylation/Deacetylation Modulates the Stability of DNA Replication Licensing Factor Cdt1

(2009) Michele A. Glozak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Docking of a Specialized PIP Box onto Chromatin-Bound PCNA Creates a Degron for the Ubiquitin Ligase CRL4Cdt2

(2009) Courtney G. Havens et al.   MOLECULAR CELL

Quaternary structure of the human Cdt1-Geminin complex regulates DNA replication licensing

(2009) V. De Marco et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors

(2009) Bulat I. Khayrutdinov et al.   PROTEIN SCIENCE

HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1

(2008) B. Miotto et al.   GENES & DEVELOPMENT

Cdt1 Forms a Complex with the Minichromosome Maintenance Protein (MCM) and Activates Its Helicase Activity

(2008) Zhiying You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human CDT1 Associates with CDC7 and Recruits CDC45 to Chromatin during S Phase

(2008) Andrea Ballabeni et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Cdt1 Lacking the Evolutionarily Conserved Region That Interacts with MCM2–7 Is Capable of Inducing Re-replication

(2008) Jamie K. Teer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdt1 and Cdc6 Are Destabilized by Rereplication-induced DNA Damage

(2008) Jonathan R. Hall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MCM9 Binds Cdt1 and Is Required for the Assembly of Prereplication Complexes

(2008) Malik Lutzmann et al.   MOLECULAR CELL

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Identification of Novel Human Cdt1-binding Proteins by a Proteomics Approach: Proteolytic Regulation by APC/CCdh1

(2007) Nozomi Sugimoto et al.   MOLECULAR BIOLOGY OF THE CELL