Linking System-Wide Impacts of RNA Polymerase Mutations to the Fitness Cost of Rifampin Resistance in Pseudomonas aeruginosa

Fitness Is Strongly Influenced by Rare Mutations of Large Effect in a Microbial Mutation Accumulation Experiment

(2014) K. Heilbron et al.   GENETICS

Genetic characterization of compensatory evolution in strains carrying rpoB Ser531Leu, the rifampicin resistance mutation most frequently found in clinical isolates

(2013) G. Brandis et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genotype-by-environment interactions due to antibiotic resistance and adaptation inEscherichia coli

(2013) A. R. Hall   JOURNAL OF EVOLUTIONARY BIOLOGY

Count-based differential expression analysis of RNA sequencing data using R and Bioconductor

(2013) Simon Anders et al.   Nature Protocols

Fitness-compensatory mutations in rifampicin-resistant RNA polymerase

(2012) Gerrit Brandis et al.   MOLECULAR MICROBIOLOGY

Altered Fatty Acid Metabolism Due to Rifampicin-Resistance Conferring Mutations in the rpoB Gene of Mycobacterium tuberculosis: Mapping the Potential of Pharmaco-metabolomics for Global Health and Personalized Medicine

(2012) Ilse du Preez et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

A Genome-Wide Analysis of Promoter-Mediated Phenotypic Noise in Escherichia coli

(2012) Olin K. Silander et al.   PLoS Genetics

Mutation of RNA Polymerase β Subunit (rpoB) Promotes hVISA-to-VISA Phenotypic Conversion of Strain Mu3

(2011) Miki Matsuo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Fitness Cost of Rifampicin Resistance in Pseudomonas aeruginosa Depends on Demand for RNA Polymerase

(2011) A. R. Hall et al.   GENETICS

Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes

(2011) Iñaki Comas et al.   NATURE GENETICS

Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosa

(2010) R. C. MacLean et al.   GENETICS

Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance

(2010) Anna Zorzet et al.   MOLECULAR MICROBIOLOGY

The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts

(2010) R. Craig MacLean et al.   NATURE REVIEWS GENETICS

Antibiotic resistance and its cost: is it possible to reverse resistance?

(2010) Dan I. Andersson et al.   NATURE REVIEWS MICROBIOLOGY

Pseudomonas Genome Database: improved comparative analysis and population genomics capability for Pseudomonas genomes

(2010) G. L. Winsor et al.   NUCLEIC ACIDS RESEARCH

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

TopHat: discovering splice junctions with RNA-Seq

(2009) Cole Trapnell et al.   BIOINFORMATICS

The Fitness Cost of Streptomycin Resistance Depends on rpsL Mutation, Carbon Source and RpoS ( S)

(2009) W. Paulander et al.   GENETICS

The Distribution of Fitness Effects of Beneficial Mutations in Pseudomonas aeruginosa

(2009) R. Craig MacLean et al.   PLoS Genetics

Linezolid Resistance in Staphylococcus aureus: Gene Dosage Effect, Stability, Fitness Costs, and Cross-Resistances

(2008) S. Besier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

(2008) L. Sandegren et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY