Host-Directed Antimicrobial Drugs with Broad-Spectrum Efficacy against Intracellular Bacterial Pathogens

Coxiella burnetiiexploits host cAMP-dependent protein kinase signalling to promote macrophage survival

(2013) Laura J. MacDonald et al.   CELLULAR MICROBIOLOGY

Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors

(2013) Maria F. Sassano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii

(2013) Erin J. van Schaik et al.   NATURE REVIEWS MICROBIOLOGY

A call for antibiotic alternatives research

(2013) Thaddeus B. Stanton   TRENDS IN MICROBIOLOGY

Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening

(2013) J. A. McDonough et al.   mBio

Bacterial Colonization of Host Cells in the Absence of Cholesterol

(2013) Stacey D. Gilk et al.   PLoS Pathogens

Host-Brucella interactions and the Brucella genome as tools for subunit antigen discovery and immunization against brucellosis

(2013) Gabriel Gomez et al.   Frontiers in Cellular and Infection Microbiology

Drug induced phospholipidosis: An acquired lysosomal storage disorder

(2012) James A. Shayman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Raloxifene attenuates Pseudomonas aeruginosa pyocyanin production and virulence

(2012) Shannan J. Ho Sui et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI

(2012) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vitamin D Inhibits Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis Infection in Macrophages through the Induction of Autophagy

(2012) Grant R. Campbell et al.   PLoS Pathogens

Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis

(2011) Ruth J. Napier et al.   Cell Host & Microbe

Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum

(2011) Qingming Xiong et al.   CELLULAR MICROBIOLOGY

Protein Kinase LegK2 Is a Type IV Secretion System Effector Involved in Endoplasmic Reticulum Recruitment and Intracellular Replication of Legionella pneumophila

(2011) Eva Hervet et al.   INFECTION AND IMMUNITY

Molecular Basis of Immunity to Rickettsial Infection Conferred through Outer Membrane Protein B

(2011) Yvonne Gar-Yun Chan et al.   INFECTION AND IMMUNITY

Effects of coadministration of natural polyphenols with doxycycline or calcium modulators on acute Chlamydia pneumoniae infection in vitro

(2011) Olli P Salin et al.   JOURNAL OF ANTIBIOTICS

Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine

(2011) E. Abbate et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Nifedipine Affects the Course of Salmonella enterica Serovar Typhimurium Infection by Modulating Macrophage Iron Homeostasis

(2011) Sabine M. Mair et al.   JOURNAL OF INFECTIOUS DISEASES

Cholesterol Depletion of Hepatoma Cells Impairs Hepatitis B Virus Envelopment by Altering the Topology of the Large Envelope Protein

(2011) C. Dorobantu et al.   JOURNAL OF VIROLOGY

Vitamin D Is Required for IFN- -Mediated Antimicrobial Activity of Human Macrophages

(2011) M. Fabri et al.   Science Translational Medicine

Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model

(2011) Choong Bum Lee et al.   UROLOGIA INTERNATIONALIS

Control of Host Cell Phosphorylation by Legionella Pneumophila

(2011) Eva Haenssler et al.   Frontiers in Microbiology

Functional Inhibitors of Acid Sphingomyelinase (FIASMAs): A Novel Pharmacological Group of Drugs with Broad Clinical Applications

(2010) Johannes Kornhuber et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The influence of donepezil and EGb 761 on the innate immunity of human leukocytes

(2010) Marta Sochocka et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now!

(2010) Leonard Amaral et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Selective Serotonin Reuptake Inhibitor Suppression of HIV Infectivity and Replication

(2010) Tami Benton et al.   PSYCHOSOMATIC MEDICINE

Inhibition of Listeria monocytogenes infection by neurological drugs

(2009) Linda A. Lieberman et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Cytotoxic effects of antipsychotic drugs implicate cholesterol homeostasis as a novel chemotherapeutic target

(2009) Erik D. Wiklund et al.   INTERNATIONAL JOURNAL OF CANCER

Smooth Brucella strains invade and replicate in human lung epithelial cells without inducing cell death

(2009) Mariana C. Ferrero et al.   MICROBES AND INFECTION

Host cell-free growth of the Q fever bacterium Coxiella burnetii

(2009) A. Omsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cholesterol-Dependent Anaplasma phagocytophilum Exploits the Low-Density Lipoprotein Uptake Pathway

(2009) Qingming Xiong et al.   PLoS Pathogens

A Small-Molecule Screen Identifies the Antipsychotic Drug Pimozide as an Inhibitor of Listeria monocytogenes Infection

(2008) L. A. Lieberman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

CME Information

(2008)   CLINICAL INFECTIOUS DISEASES

Characterization of a Coxiella burnetii ftsZ Mutant Generated by Himar1 Transposon Mutagenesis

(2008) P. A. Beare et al.   JOURNAL OF BACTERIOLOGY

Effect of donepezil on innate antiviral immunity of human leukocytes

(2008) Marta Sochocka et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

A Cholesterol Biosynthesis Inhibitor Blocks Staphylococcus aureus Virulence

(2008) C.-I Liu et al.   SCIENCE

Type IV Secretion-Dependent Activation of Host MAP Kinases Induces an Increased Proinflammatory Cytokine Response to Legionella pneumophila

(2008) Sunny Shin et al.   PLoS Pathogens