Challenges in selectivity, specificity and quantitation range of ligand-binding assays: case studies using a microfluidics platform

Assay Formats: Recommendation for Best Practices and Harmonization from the Global Bioanalysis Consortium Harmonization Team

(2013) Sherri Dudal et al.   AAPS Journal

Bioanalytical platform comparison using a generic human IgG PK assay format

(2013) Beth A. Leary et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Analytical assay platforms for soluble target engagement biomarkers: old favorites and emerging technologies

(2013) Joanne Goodman et al.   Bioanalysis

The Gyrolab™ immunoassay system: a platform for automated bioanalysis and rapid sample turnaround

(2013) Kristy J Fraley et al.   Bioanalysis

Rapid development of multiple ‘fit-for-purpose’ assays on an automatic microfluidic system using a streamlined process in support of early biotherapeutics discovery programs

(2013) Rong Liu et al.   Bioanalysis

Development and validation of an alpha fetoprotein immunoassay using Gyros technology

(2012) Allison M. Given et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Validation of a gyrolab™ assay for quantification of rituximab in human serum

(2012) Xiaodong F. Liu et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development

(2011) Jean W. Lee et al.   AAPS Journal

Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development

(2010) Alvydas Mikulskis et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Application of the Gyrolab™ platform to ligand-binding assays: a user’s perspective

(2010) Johanna R Mora et al.   Bioanalysis

Application of miniaturized immunoassays to discovery pharmacokinetic bioanalysis

(2010) Jeanette Roman et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS