Overcoming bioanalytical challenges in an Onglyza®intravenous [14C]microdose absolute bioavailability study with accelerator MS

Liquid chromatography and tandem mass spectrometry method for the quantitative determination of saxagliptin and its major pharmacologically active 5-monohydroxy metabolite in human plasma: Method validation and overcoming specific and non-specific binding at low concentrations

(2012) Xiaohui (Sophia) Xu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Precision and Accuracy in the Quantitative Analysis of Biological Samples by Accelerator Mass Spectrometry: Application in Microdose Absolute Bioavailability Studies

(2011) Lan Gao et al.   ANALYTICAL CHEMISTRY

Metabolism and Disposition of [14C]BMS-690514, an ErbB/Vascular Endothelial Growth Factor Receptor Inhibitor, after Oral Administration to Humans

(2010) L. J. Christopher et al.   DRUG METABOLISM AND DISPOSITION

Analytical validation of accelerator mass spectrometry for pharmaceutical development

(2010) Bradly D Keck et al.   Bioanalysis

Accelerator mass spectrometry best practices for accuracy and precision in bioanalytical14C measurements

(2010) John S Vogel et al.   Bioanalysis

Accelerator mass spectrometry-enabled studies: current status and future prospects

(2010) Ali Arjomand   Bioanalysis

Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition

(2009) Mark Kirby et al.   CLINICAL SCIENCE

Pharmacokinetics of the Dipeptidyl Peptidase 4 Inhibitor Saxagliptin in Rats, Dogs, and Monkeys and Clinical Projections

(2009) A. Fura et al.   DRUG METABOLISM AND DISPOSITION

BioMICADAS: Compact next generation AMS system for pharmaceutical science

(2009) Tim Schulze-König et al.   NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS

Microdosing: a valuable tool for accelerating drug development and the role of bioanalytical methods in meeting the challenge

(2009) Robert MJ Ings   Bioanalysis

Biological accelerator mass spectrometry at Uppsala University

(2008) Mehran Salehpour et al.   APPLIED RADIATION AND ISOTOPES