MS-based approaches for studying the pharmacokinetics of protein drugs

Recombinant immunotherapeutics: current state and perspectives regarding the feasibility and market

(2010) Chung-Jr Huang et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Characterization of protein therapeutics by mass spectrometry: recent developments and future directions

(2010) Guodong Chen et al.   DRUG DISCOVERY TODAY

Natriuretic peptides in heart failure: where we are, where we are going

(2010) Alberto Palazzuoli et al.   Internal and Emergency Medicine

Combined use of immunoassay and two-dimensional liquid chromatography mass spectrometry for the detection and identification of metabolites from biotherapeutic pharmacokinetic samples

(2010) Robert E. Murphy et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Targeted Ion Parking for the Quantitation of Biotherapeutic Proteins: Concepts and Preliminary Data

(2010) J. Larry Campbell et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Liquid chromatography/tandem mass spectrometry assay for the absolute quantification of the expected circulating apelin peptides in human plasma

(2010) Cédric Mesmin et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Critical comparison of MS and immunoassays for the bioanalysis of therapeutic antibodies

(2010) Eric Ezan et al.   Bioanalysis

Bioanalysis of recombinant proteins and antibodies by mass spectrometry

(2009) Eric Ezan et al.   ANALYST

Determination of Taspoglutide in Human and Animal Plasma Using Liquid Chromatography−Tandem Mass Spectrometry with Orthogonal Column-Switching

(2009) Katja Heinig et al.   ANALYTICAL CHEMISTRY

Synthetic therapeutic peptides: science and market

(2009) Patrick Vlieghe et al.   DRUG DISCOVERY TODAY

A sensitive and high-throughput LC–MS/MS method for the quantification of pegylated-interferon-α2a in human serum using monolithic C18 solid phase extraction for enrichment

(2009) Ziping Yang et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

(2009) Andrew N. Hoofnagle et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Towards Absolute Quantification of Therapeutic Monoclonal Antibody in Serum by LC−MS/MS Using Isotope-Labeled Antibody Standard and Protein Cleavage Isotope Dilution Mass Spectrometry

(2008) Olivier Heudi et al.   ANALYTICAL CHEMISTRY

Assessing Immunogenicity in the Presence of Excess Protein Therapeutic Using Immunoprecipitation and Quantitative Mass Spectrometry

(2008) Hendrik Neubert et al.   ANALYTICAL CHEMISTRY

Quantitative bioanalysis of peptides by liquid chromatography coupled to (tandem) mass spectrometry

(2008) Irene van den Broek et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Protein Standard Absolute Quantification (PSAQ) for improved investigation of staphylococcal food poisoning outbreaks

(2008) Alain Dupuis et al.   PROTEOMICS

Quantitative aspects of the analysis of the monoclonal antibody trastuzumab using high-performance liquid chromatography coupled with electrospray mass spectrometry

(2007) Carola W.N. Damen et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS