Metabolites in safety testing

Safety Assessment of Drug Metabolites: Implications of Regulatory Guidance and Potential Application of Genetically Engineered Mouse Models that Express Human P450s

(2009) Mark W. Powley et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The Role of Gut Microbiota in Drug Response

(2009) I. Wilson et al.   CURRENT PHARMACEUTICAL DESIGN

Covalent Binding of Phenylacetic Acid to Protein in Incubations with Freshly Isolated Rat Hepatocytes

(2009) M. P. Grillo et al.   DRUG METABOLISM AND DISPOSITION

Serotonergic drugs and valvular heart disease

(2009) Richard B Rothman et al.   Expert Opinion On Drug Safety

Simultaneous quantification of losartan and active metabolite in human plasma by liquid chromatography–tandem mass spectrometry using irbesartan as internal standard

(2009) Budi Prasaja et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Safety testing of metabolites: Expectations and outcomes

(2008) K. Sandy Pang   CHEMICO-BIOLOGICAL INTERACTIONS