A new era for functional labeling of neurons: activity-dependent promoters have come of age

Transcription of the Immediate-Early Gene Arc in CA1 of the Hippocampus Reveals Activity Differences along the Proximodistal Axis That Are Attenuated by Advanced Age

(2013) A. L. Hartzell et al.   JOURNAL OF NEUROSCIENCE

Optical control of mammalian endogenous transcription and epigenetic states

(2013) Silvana Konermann et al.   NATURE

Mapping brain circuitry with a light microscope

(2013) Pavel Osten et al.   NATURE METHODS

Functional labeling of neurons and their projections using the synthetic activity–dependent promoter E-SARE

(2013) Takashi Kawashima et al.   NATURE METHODS

Arc/Arg3.1 Is a Postsynaptic Mediator of Activity-Dependent Synapse Elimination in the Developing Cerebellum

(2013) Takayasu Mikuni et al.   NEURON

Permanent Genetic Access to Transiently Active Neurons via TRAP: Targeted Recombination in Active Populations

(2013) Casey J. Guenthner et al.   NEURON

Creating a False Memory in the Hippocampus

(2013) S. Ramirez et al.   SCIENCE

Long-Distance Integration of Nuclear ERK Signaling Triggered by Activation of a Few Dendritic Spines

(2013) S. Zhai et al.   SCIENCE

Nonlinear Decoding and Asymmetric Representation of Neuronal Input Information by CaMKIIα and Calcineurin

(2013) Hajime Fujii et al.   Cell Reports

Inverse Synaptic Tagging of Inactive Synapses via Dynamic Interaction of Arc/Arg3.1 with CaMKIIβ

(2012) Hiroyuki Okuno et al.   CELL

Elimination of Dendritic Spines with Long-Term Memory Is Specific to Active Circuits

(2012) J. Sanders et al.   JOURNAL OF NEUROSCIENCE

Medial Prefrontal Cortex Neuronal Activation and Synaptic Alterations after Stress-Induced Reinstatement of Palatable Food Seeking: A Study Using c-fos-GFP Transgenic Female Rats

(2012) C. Cifani et al.   JOURNAL OF NEUROSCIENCE

Optogenetic stimulation of a hippocampal engram activates fear memory recall

(2012) Xu Liu et al.   NATURE

Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay

(2012) Alexandre Melnikov et al.   NATURE BIOTECHNOLOGY

Spatiotemporal control of gene expression by a light-switchable transgene system

(2012) Xue Wang et al.   NATURE METHODS

Serial two-photon tomography for automated ex vivo mouse brain imaging

(2012) Timothy Ragan et al.   NATURE METHODS

Silent synapses in selectively activated nucleus accumbens neurons following cocaine sensitization

(2012) Eisuke Koya et al.   NATURE NEUROSCIENCE

Functional anatomy of neural circuits regulating fear and extinction

(2012) E. Knapska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of a Synthetic Memory Trace

(2012) A. R. Garner et al.   SCIENCE

Rapid synaptic potentiation within the anterior cingulate cortex mediates trace fear learning

(2012) Giannina Descalzi et al.   Molecular Brain

Bioluminescence imaging of Arc expression enables detection of activity-dependent and plastic changes in the visual cortex of adult mice

(2010) Hironori Izumi et al.   Brain Structure & Function

SRF binding to SRE 6.9 in the Arc promoter is essential for LTD in cultured Purkinje cells

(2010) Constance Smith-Hicks et al.   NATURE NEUROSCIENCE

An Embedded Subnetwork of Highly Active Neurons in the Neocortex

(2010) Lina Yassin et al.   NEURON

Regulation and function of immediate-early genes in the brain: Beyond neuronal activity markers

(2010) Hiroyuki Okuno   NEUROSCIENCE RESEARCH

Noninvasive bioluminescence imaging of c-fos expression in the mouse barrel cortex

(2009) Makoto Wada et al.   BEHAVIOURAL BRAIN RESEARCH

The Serum Response Factor and a Putative Novel Transcription Factor Regulate Expression of the Immediate-Early Gene Arc/Arg3.1 in Neurons

(2009) S. A. Pintchovski et al.   JOURNAL OF NEUROSCIENCE

Fluorescent Arc/Arg3.1 indicator mice: A versatile tool to study brain activity changes in vitro and in vivo

(2009) Valery Grinevich et al.   JOURNAL OF NEUROSCIENCE METHODS

Targeted disruption of cocaine-activated nucleus accumbens neurons prevents context-specific sensitization

(2009) Eisuke Koya et al.   NATURE NEUROSCIENCE

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

Signaling Mechanisms Linking Neuronal Activity to Gene Expression and Plasticity of the Nervous System

(2008) Steven W. Flavell et al.   Annual Review of Neuroscience

In vivo and in vitro visualization of gene expression dynamics over extensive areas of the brain

(2008) M EGUCHI et al.   NEUROIMAGE

Synaptic activity-responsive element in the Arc/Arg3.1 promoter essential for synapse-to-nucleus signaling in activated neurons

(2008) T. Kawashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spine-Type-Specific Recruitment of Newly Synthesized AMPA Receptors with Learning

(2008) N. Matsuo et al.   SCIENCE