ER stress and unfolded protein response in amyotrophic lateral sclerosis—a controversial role of protein disulphide isomerase

Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis

(2015) Marianna Marino et al.   NEUROBIOLOGY OF AGING

Inactivation of mammalian Ero1α is catalysed by specific protein disulfide-isomerases

(2014) Colin Shepherd et al.   BIOCHEMICAL JOURNAL

Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models

(2014) Sami J Barmada et al.   Nature Chemical Biology

Potential Effect of S-Nitrosylated Protein Disulfide Isomerase on Mutant SOD1 Aggregation and Neuronal Cell Death in Amyotrophic Lateral Sclerosis

(2013) Gye Sun Jeon et al.   MOLECULAR NEUROBIOLOGY

Endoplasmic reticulum stress and the ER mitochondria calcium cycle in amyotrophic lateral sclerosis

(2012) Janin Lautenschlaeger et al.   Amyotrophic Lateral Sclerosis

Redox signaling loops in the unfolded protein response

(2012) Arisa Higa et al.   CELLULAR SIGNALLING

Protein disulfide isomerase in ALS mouse glia links protein misfolding with NADPH oxidase-catalyzed superoxide production

(2012) M. Jaronen et al.   HUMAN MOLECULAR GENETICS

Bacitracin inhibits the reductive activity of protein disulfide isomerase by disulfide bond formation with free cysteines in the substrate-binding domain

(2011) Nina Dickerhof et al.   FEBS Journal

Glutathione- and non-glutathione-based oxidant control in the endoplasmic reticulum

(2011) C. Appenzeller-Herzog   JOURNAL OF CELL SCIENCE

Calcium dysregulation in amyotrophic lateral sclerosis

(2010) Julian Grosskreutz et al.   CELL CALCIUM

Oxidative folding in the endoplasmic reticulum: Towards a multiple oxidant hypothesis?

(2010) Éva Margittai et al.   FEBS LETTERS

NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis

(2010) Gang Li et al.   JOURNAL OF CELL BIOLOGY

Endoplasmic Reticulum Stress in Motor Neurons of the Spinal Cord in Sporadic Amyotrophic Lateral Sclerosis

(2010) Shoichi Sasaki   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins

(2010) Benjamin G Hoffstrom et al.   Nature Chemical Biology

Non-invasive diffusion tensor imaging detects white matter degeneration in the spinal cord of a mouse model of amyotrophic lateral sclerosis

(2010) Clare K. Underwood et al.   NEUROIMAGE

Mechanisms and Implications of Reactive Oxygen Species Generation During the Unfolded Protein Response: Roles of Endoplasmic Reticulum Oxidoreductases, Mitochondrial Electron Transport, and NADPH Oxidase

(2009) Célio X.C. Santos et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein disulfide isomerase overexpression in vascular smooth muscle cells induces spontaneous preemptive NADPH oxidase activation and Nox1 mRNA expression: Effects of nitrosothiol exposure

(2009) Denise C. Fernandes et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

(2009) C. Hetz et al.   GENES & DEVELOPMENT

Protein disulfide isomerase (PDI) associates with NADPH oxidase and is required for phagocytosis of Leishmania chagasi promastigotes by macrophages

(2009) Célio X. C. Santos et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A role for motoneuron subtype–selective ER stress in disease manifestations of FALS mice

(2009) Smita Saxena et al.   NATURE NEUROSCIENCE

Novel Role of Protein Disulfide Isomerase in the Regulation of NADPH Oxidase Activity: Pathophysiological Implications in Vascular Diseases

(2008) Francisco R.M. Laurindo et al.   ANTIOXIDANTS & REDOX SIGNALING

ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1

(2008) H. Nishitoh et al.   GENES & DEVELOPMENT

VAPB interacts with and modulates the activity of ATF6

(2008) C. Gkogkas et al.   HUMAN MOLECULAR GENETICS

Deleterious Role of Superoxide Dismutase in the Mitochondrial Intermembrane Space

(2008) Gundars Goldsteins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cu/Zn Superoxide Dismutase Typical for Familial Amyotrophic Lateral Sclerosis Increases the Vulnerability of Mitochondria and Perturbs Ca2+ Homeostasis in SOD1G93A Mice

(2008) M. K. Jaiswal et al.   MOLECULAR PHARMACOLOGY

Mutant SOD1 from spinal cord of G93A rats is destabilized and binds to inner mitochondrial membrane

(2008) Toni Ahtoniemi et al.   NEUROBIOLOGY OF DISEASE

Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis

(2008) Julie D. Atkin et al.   NEUROBIOLOGY OF DISEASE

Spinal anterior horn cells in sporadic amyotrophic lateral sclerosis show ribosomal detachment from, and cisternal distention of the rough endoplasmic reticulum

(2008) K. Oyanagi et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis

(2008) C. Hetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antioxidants reduce endoplasmic reticulum stress and improve protein secretion

(2008) J. D. Malhotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Superoxide dismutase 1 mutants related to amyotrophic lateral sclerosis induce endoplasmic stress in neuro2a cells

(2007) Yeo Kyoung Oh et al.   JOURNAL OF NEUROCHEMISTRY