Mitochondrial dysfunction induced by frataxin deficiency is associated with cellular senescence and abnormal calcium metabolism

The endoplasmic reticulum–mitochondria connection: One touch, multiple functions

(2013) Saverio Marchi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Programmed Cell Senescence during Mammalian Embryonic Development

(2013) Daniel Muñoz-Espín et al.   CELL

Apoptotic cell death and altered calcium homeostasis caused by frataxin depletion in dorsal root ganglia neurons can be prevented by BH4 domain of Bcl-xL protein

(2013) S. Mincheva-Tasheva et al.   HUMAN MOLECULAR GENETICS

Mitochondrial pathophysiology in Friedreich's ataxia

(2013) Pilar González-Cabo et al.   JOURNAL OF NEUROCHEMISTRY

Prevalence gradients of Friedreich's Ataxia and R1b haplotype in Europe co-localize, suggesting a common Palaeolithic origin in the Franco-Cantabrian ice age refuge

(2013) Pierre Vankan   JOURNAL OF NEUROCHEMISTRY

Cardiomyopathy of Friedreich Ataxia

(2013) Frank Weidemann et al.   JOURNAL OF NEUROCHEMISTRY

Friedreich Ataxia: Neuropathology Revised

(2013) Arnulf H. Koeppen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry

(2013) David Pla-Martín et al.   NEUROBIOLOGY OF DISEASE

Mitochondria: In Sickness and in Health

(2012) Jodi Nunnari et al.   CELL

Mitochondrial Ca2+ and neurodegeneration

(2012) Tito Calì et al.   CELL CALCIUM

Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia

(2012) A. Hick et al.   Disease Models & Mechanisms

2-Hydroxyoleic Acid Induces ER Stress and Autophagy in Various Human Glioma Cell Lines

(2012) Amaia Marcilla-Etxenike et al.   PLoS One

SCaMC-1 promotes cancer cell survival by desensitizing mitochondrial permeability transition via ATP/ADP-mediated matrix Ca2+ buffering

(2011) J Traba et al.   CELL DEATH AND DIFFERENTIATION

Silencing of frataxin gene expression triggers p53-dependent apoptosis in human neuron-like cells

(2011) G. M. Palomo et al.   HUMAN MOLECULAR GENETICS

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

A rapid, noninvasive immunoassay for frataxin: Utility in assessment of Friedreich ataxia

(2010) Eric C. Deutsch et al.   MOLECULAR GENETICS AND METABOLISM

Flavin Adenine Dinucleotide Rescues the Phenotype of Frataxin Deficiency

(2010) Pilar Gonzalez-Cabo et al.   PLoS One

Frataxin deficiency induces Schwann cell inflammation and death

(2009) Chunye Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Limitations in a frataxin knockdown cell model for Friedreich ataxia in a high-throughput drug screen

(2009) Nadège Calmels et al.   BMC Neurology

Increased Endoplasmic Reticulum Stress and Decreased Proteasomal Function in Lafora Disease Models Lacking the Phosphatase Laforin

(2009) Santiago Vernia et al.   PLoS One

Quality control of mitochondria: protection against neurodegeneration and ageing

(2008) Takashi Tatsuta et al.   EMBO JOURNAL

The effects of frataxin silencing in HeLa cells are rescued by the expression of human mitochondrial ferritin

(2007) Isabella Zanella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE