Stem cell-based treatments against stroke: observations from human proof-of-concept studies and considerations regarding clinical applicability

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Adult neurogenesis: bridging the gap between mice and humans

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Vascular regulation of adult neurogenesis under physiological and pathological conditions

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Human bone marrow mesenchymal stem/stromal cells produce efficient localization in the brain and enhanced angiogenesis after intra-arterial delivery in rats with cerebral ischemia, but this is not translated to behavioral recovery

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Adult neural stem cells and their niche: a dynamic duo during homeostasis, regeneration, and aging

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Cell-based therapy for ischemic stroke

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Intra-Arterial Delivery Is Not Superior to Intravenous Delivery of Autologous Bone Marrow Mononuclear Cells in Acute Ischemic Stroke

(2013) Bing Yang et al.   STROKE

Stem cell therapy: A clinical trial of stroke

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Proximity of brain infarcts to regions of endogenous neurogenesis and involvement of striatum in ischaemic stroke

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Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation

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Systemically administered human bone marrow-derived mesenchymal stem home into peripheral organs but do not induce neuroprotective effects in the MCAo-mouse model for cerebral ischemia

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Therapeutic Effects of hMAPC and hMSC Transplantation after Stroke in Mice

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Safety of Cell Therapy with Mesenchymal Stromal Cells (SafeCell): A Systematic Review and Meta-Analysis of Clinical Trials

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Transduction of Neural Precursor Cells with TAT-Heat Shock Protein 70 Chaperone: Therapeutic Potential Against Ischemic Stroke after Intrastriatal and Systemic Transplantation

(2012) Thorsten R. Doeppner et al.   STEM CELLS

Intra-Arterial Bone Marrow Mononuclear Cells in Ischemic Stroke

(2012) Francisco Moniche et al.   STROKE

Human Adult Dental Pulp Stem Cells Enhance Poststroke Functional Recovery Through Non-Neural Replacement Mechanisms

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Intravenous autologous bone marrow mononuclear cells for ischemic stroke

(2011) Sean I. Savitz et al.   ANNALS OF NEUROLOGY

Intravenous administration of auto serum-expanded autologous mesenchymal stem cells in stroke

(2011) O. Honmou et al.   BRAIN

The tumorigenicity of diploid and aneuploid human pluripotent stem cells

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Adverse Effects of Bone Marrow Stromal Cell Treatment of Stroke in Diabetic Rats

(2011) Jieli Chen et al.   STROKE

Transplantation of TAT-Bcl-xL-transduced neural precursor cells: Long-term neuroprotection after stroke

(2010) Thorsten R. Doeppner et al.   NEUROBIOLOGY OF DISEASE

Mesenchymal stem cell transplantation modulates neuroinflammation in focal cerebral ischemia: Contribution of fractalkine and IL-5

(2010) Abdullah Md. Sheikh et al.   NEUROBIOLOGY OF DISEASE

Safety of autologous bone marrow mononuclear cell transplantation in patients with nonacute ischemic stroke

(2010) Valeria Battistella et al.   Regenerative Medicine

A Long-Term Follow-Up Study of Intravenous Autologous Mesenchymal Stem Cell Transplantation in Patients With Ischemic Stroke

(2010) Jin Soo Lee et al.   STEM CELLS

Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms

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Therapeutic benefits of human mesenchymal stem cells derived from bone marrow after global cerebral ischemia

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Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats

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Migration and homing of bone-marrow mononuclear cells in chronic ischemic stroke after intra-arterial injection

(2009) Lea Mirian Barbosa da Fonseca et al.   EXPERIMENTAL NEUROLOGY

TAT-Bcl-xL improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia

(2009) Thorsten R. Doeppner et al.   NEUROBIOLOGY OF DISEASE

Optimizing the success of cell transplantation therapy for stroke

(2009) Tonya M. Bliss et al.   NEUROBIOLOGY OF DISEASE

Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model

(2008) Seung-Wan Yoo et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Why are MSCs therapeutic? New data: new insight

(2008) AI Caplan   JOURNAL OF PATHOLOGY

Concise Review: Adult Multipotent Stromal Cells and Cancer: Risk or Benefit?

(2008) Gwendal Lazennec et al.   STEM CELLS

Hematopoietic Stem Cells Reduce Postischemic Inflammation and Ameliorate Ischemic Brain Injury

(2008) Sönke Schwarting et al.   STROKE

Neural stem/precursor cells for the treatment of ischemic stroke

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