Article
Psychology, Multidisciplinary
Kaiyi Zhu, Wei Yang, Zesheng Ying, Yingjie Cai, XiaoJiao Peng, Nijia Zhang, Hailang Sun, Yuanqi Ji, Ming Ge
Summary: This study investigated the long-term quality of life (QoL) of children with cerebellar mutism syndrome (CMS) and identified risk factors for a low QoL. Children with CMS had significantly lower QoL scores compared to those without CMS, and factors such as older age, chemotherapy, and ventriculoperitoneal (VP) shunt placement were associated with lower QoL scores. The study highlights the need for early rehabilitation for CMS patients.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Rebecca van Kalsbeek, Melissa Hudson, Renee L. Mulder, Matthew M. Ehrhardt, Daniel Green, Daniel Mulrooney, Jessica C. Hakkert, Jaap M. den Hartogh, Anouk M. Nijenhuis, Hanneke van Santen, Antoinette Y. N. Schouten-van Meeteren, Harm van Tinteren, Lisanne A. Verbruggen, Heather Conklin, Lisa Jacola, Rachel Tillery Webster, Marita Partanen, Wouter J. W. J. Kollen, Martha M. Grootenhuis, Rob Pieters, Leontien C. M. Kremer
Summary: The International Childhood Cancer Outcome Project group developed a core outcome set to measure the quality of care for 17 types of childhood cancers. The set includes physical core outcomes and aspects of quality of life, and can be used to evaluate treatment effectiveness and patient well-being.
Article
Chemistry, Physical
Yuxi Wang, Bo Qiu, Lingfei Hu, Gang Lu, Tao Xu
Summary: The reverse concerted metalation-deprotonation (CMD) process is proposed as a key step in rationalizing a newly discovered Rh-catalyzed C-C/olefin-H cascade reaction, which features redox-neutral conditions with 100% atom economy, broad substrate scope, and high efficiency (23 examples, up to 85% yield). DFT calculations suggest that the reverse CMD process is crucial in kinetic override of the normal cut and sew process, leading to the activation of olefinic C-H bonds as the predominant pathway.
Article
Medicine, Research & Experimental
Giovanna Pachele Parizotto, Livia Victorino de Souza, Fernanda Thomazini, Monica Simon Prado, Juan Sebastian Henao Agudelo, Danilo Candido de Almeida, Maria do Carmo Franco
Summary: This study found that children with low birth weight had increased circulating numbers of CD31+/annexin V+ and CD144+ EMPs, and low birth weight and elevated CD31+/annexin V+ EMP levels were significant risk factors for the presence of microvascular endothelial dysfunction.
Article
Oncology
Richard Huan Xu, Dong Dong
Summary: This study examined the difference between self- and proxy-reported health-related quality of life (HRQoL) in Chinese lymphoma survivors and its association with sociodemographic and health characteristics. The results showed that self-reported patients had higher physical, role, and emotional functioning, but lower cognitive and social functioning compared to proxy-reported patients. However, the difference in HRQoL between self- and proxy-reported patients was not significant among different subtypes of lymphoma.
Article
Telecommunications
Rasoul Roustaei, Hamid Haj Seyyed Javadi, Midia Reshadi
Summary: Due to the heterogeneity of devices and resource limitations in the Internet of Things, simplifying and lightening algorithms in this domain has become an interesting study area. A critical aspect in the Internet of Things is the establishment of secret keys for secure communication. The importance of communication security and the need for lightweight algorithms have motivated the development of a lightweight key agreement protocol. This article presents a lightweight method for key agreement, analyzing its performance and showing its resistance to attacks.
WIRELESS PERSONAL COMMUNICATIONS
(2023)
Article
Cell Biology
Rida Rehman, Michael Miller, Sruthi Sankari Krishnamurthy, Jacob Kjell, Lobna Elsayed, Stefanie M. Hauck, Florian Olde Heuvel, Alison Conquest, Akila Chandrasekar, Albert Ludolph, Tobias Boeckers, Medhanie A. Mulaw, Magdalena Goetz, Maria Cristina Morganti-Kossmann, Aya Takeoka, Francesco Roselli
Summary: This study investigates the role of tyrosine-kinase signaling in traumatic brain injury (TBI) using array phosphoproteomics. The findings reveal that Met/HGFR serves as a modulator of early neuroinflammation in TBI and inhibition of Met/HGFR can improve neuronal survival and motor recovery.
Article
Endocrinology & Metabolism
Steven Allender, Liliana Orellana, Nic Crooks, Kristy A. Bolton, Penny Fraser, Andrew Dwight Brown, Ha Le, Janette Lowe, Kayla de la Haye, Lynne Millar, Marjorie Moodie, Boyd Swinburn, Colin Bell, Claudia Strugnell
Summary: The study found that the Whole of Systems Trial of Prevention Strategies for Childhood Obesity had a positive impact on reducing takeaway food intake and improving health-related quality of life, but the effects on BMI z scores and overweight/obesity prevalence were not significant.
Article
Oncology
Veronika Koutna, Marek Blatny, Martin Jelinek
Summary: In pediatric cancer settings, parents tend to underestimate the quality of life and posttraumatic growth (PTG) of their children, showing poor concordance with children's own reports. Parental reports of children's PTG are influenced by their own level of PTG, indicating that parents are not very accurate reporters of PTG in the child.
Article
Ophthalmology
Alexandra O. Robertson, Valerija Tadic, Lisanne A. Horvat-Gitsels, Mario Cortina-Borja, Jugnoo S. Rahi
Summary: This study investigated disagreement between children's self-reported vision-related quality of life and functional vision and their parents' proxy-reports. The results showed that children generally rated themselves better than their parents did, and parents both underestimated and overestimated their child's quality of life. With increasing age, children were more likely to rate their quality of life better than their parents.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Yao Wu, Cong Zhao, Yanzhuang Su, Sason Shaik, Wenzhen Lai
Summary: The copper-dependent formylglycine-generating enzyme (FGE) catalyzes the oxygen-dependent oxidation of specific peptidyl-cysteine residues to formylglycine. Our QM/MM calculations provide a likely mechanism for this transformation, suggesting the involvement of a triplet Cu-II-superoxide complex and a Cu-I-alkylperoxo intermediate. The results also indicate that the aldehyde oxygen of the final product originates from O-2.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Oncology
Deborah Tomlinson, Erin Plenert, Grace Dadzie, Robyn Loves, Sadie Cook, Tal Schechter, L. Lee Dupuis, Lillian Sung
Summary: This study aims to qualitatively describe reasons for disagreement in ratings of bothersome symptoms between child self-report and parent proxy-report. Through the analysis, themes were identified explaining the discrepancies, such as differing perception, understanding difficulties, lack of communication, projection, and discrepancies. Enhancing communication between children and parents about symptom reporting may reduce some of the disagreements identified. Future research should focus on methods that encourage communication between children with cancer and their caregivers.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Critical Care Medicine
Amery Treble-Barna, Shari L. Wade, Valentina Pilipenko, Lisa J. Martin, Keith Owen Yeates, H. Gerry Taylor, Brad G. Kurowski
Summary: The study investigated the differential effect of BDNF Val66Met polymorphism on behavioral adjustment in children with TBI compared to children with OI. Met carriers in the TBI group showed a trend of poorer behavioral adjustment relative to Val/Val homozygotes, while the opposite trend was observed in the OI group. These within-group differences did not reach statistical significance.
JOURNAL OF NEUROTRAUMA
(2022)
Article
Pediatrics
Ellen van der Plas, T. Leigh Spencer Noakes, Darci T. Butcher, Rosanna Weksberg, Laura Galin-Corini, Elizabeth A. Wanstall, Patrick Te, Laura Hopf, Sharon Guger, Johann Hitzler, Russell J. Schachar, Shinya Ito, Brian J. Nieman
Summary: The study evaluated cognition, behavior, and quality of life in child and adolescent acute lymphoblastic leukemia (ALL) survivors, finding impairments in survivors in cognition, behavior, and motor skills, associated with reduced quality of life. Math difficulties and behavioral problems were found to increase the risk for reduced quality of life in ALL survivors, suggesting that even mild impairments have broad implications. Screening and early intervention targeting cognitive and behavioral function may enhance quality of life for ALL survivors.
PEDIATRIC RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Naresh Bhuma, Ludivine Lebedel, Hiroki Yamashita, Yutaka Shimizu, Zahra Abada, Ana Arda, Jerome Desire, Bastien Michelet, Agnes Martin-Mingot, Ali Abou-Hassan, Masahiro Takumi, Jerome Marrot, Jesus Jimenez-Barbero, Aiichiro Nagaki, Yves Bleriot, Sebastien Thibaudeau
Summary: Ferrier's research in 1962 on the transformation of glycals into unsaturated glycosyl derivatives involved an alpha,beta unsaturated glycosyl cation. Through NMR-based structural analysis and DFT calculations, this elusive ionic species was characterized, leading to the synthesis of unsaturated nitrogen-containing C-aryl glycosides and C-alkyl glycosides under different conditions.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Clinical Neurology
Edith N. Botchway, Celia Godfrey, Vicki Anderson, Cathy Catroppa
JOURNAL OF HEAD TRAUMA REHABILITATION
(2019)
Article
Neurosciences
Travis Wearne, Vicki Anderson, Cathy Catroppa, Angela Morgan, Jennie Ponsford, Robyn Tate, Tamara Ownsworth, Leanne Togher, Jennifer Fleming, Jacinta Douglas, Kimberley Docking, Linda Sigmundsdottir, Heather Francis, Cynthia Honan, Skye McDonald
NEUROPSYCHOLOGICAL REHABILITATION
(2020)
Article
Rehabilitation
Edith N. Botchway, Celia Godfrey, Christian L. Nicholas, Stephen Hearps, Vicki Anderson, Cathy Catroppa
DISABILITY AND REHABILITATION
(2020)
Article
Critical Care Medicine
Nicholas P. Ryan, Jonathan Reyes, Louise Crossley, Miriam H. Beauchamp, Cathy Catroppa, Vicki A. Anderson
JOURNAL OF NEUROTRAUMA
(2019)
Article
Clinical Neurology
Clara Chavez Arana, Cathy Catroppa, Guillermina Yanez-Tellez, Belen Prieto-Corona, Miguel A. de Leon, Antonio Garcia, Roberto Gomez-Raygoza, Stephen J. C. Hearps, Vicki Anderson
DEVELOPMENTAL NEUROREHABILITATION
(2020)
Article
Neurosciences
Carola Tuerk, Fanny Degeilh, Cathy Catroppa, Julian J. Dooley, Michael Kean, Vicki Anderson, Miriam H. Beauchamp
HUMAN BRAIN MAPPING
(2020)
Article
Clinical Neurology
Joy Noelle Yumul, Audrey McKinlay, Martin Than, Vicki Anderson, Cathy Catroppa
JOURNAL OF HEAD TRAUMA REHABILITATION
(2020)
Article
Psychology, Developmental
Daniel J. King, Stefano Seri, Richard Beare, Cathy Catroppa, Vicki A. Anderson, Amanda G. Wood
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2020)
Article
Neurosciences
Edith N. Botchway, Celia Godfrey, Nicholas P. Ryan, Stephen Hearps, Christian L. Nicholas, Vicki A. Anderson, Cathy Catroppa
Article
Critical Care Medicine
Nicholas P. Ryan, Vicki A. Anderson, Erin D. Bigler, Maureen Dennis, H. Gerry Taylor, Kenneth H. Rubin, Kathryn Vannatta, Cynthia A. Gerhardt, Terry Stancin, Miriam H. Beauchamp, Stephen Hearps, Cathy Catroppa, Keith Owen Yeates
Summary: This international multi-cohort study synthesized data from two large observational cohort studies on child TBI, revealing a brain-injury specific effect on Theory of Mind (ToM) abilities. The study highlighted the importance of ToM deficits in linking severe child TBI to long-term social adjustment difficulties. Large-scale data harmonization projects were emphasized for improving the quality of evidence regarding TBI outcomes.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Psychology, Developmental
Nicholas P. Ryan, Cathy Catroppa, Nathan Hughes, Felicity L. Painter, Stephen Hearps, Miriam H. Beauchamp, Vicki A. Anderson
Summary: This study found that severe TBI is associated with volumetric differences within the CEN and its hub regions. Compared to controls, the TBI group showed significantly worse EF, which was linked to more frequent anti-social behaviors and abnormal CEN morphometry. Reduced EF was found to mediate the prospective relationship between post-injury CEN structural differences and increased anti-social behavior.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2021)
Review
Psychology, Clinical
Zhi Xiang On, Nicholas P. Ryan, Monika Konjarski, Cathy Catroppa, Robyn Stargatt
Summary: Recent studies have shown significant impacts of childhood traumatic brain injury on social cognition, particularly in theory of Mind (ToM) and pragmatic language tasks. Despite relatively intact basic social cognitive skills, children with TBI are vulnerable to deficits in higher-order aspects of social cognition such as ToM and pragmatic language. Further research using larger samples and longitudinal prospective studies are needed to evaluate the effects of injury on social cognitive outcomes and recovery after pediatric TBI.
NEUROPSYCHOLOGY REVIEW
(2022)
Review
Psychology, Clinical
Joy Noelle Yumul, Louise Crowe, Cathy Catroppa, Vicki Anderson, Audrey McKinlay
Summary: Research identified the experience of post-concussive signs and symptoms in children under 5 years old and explored the presentation and progression of post-concussive symptoms, highlighting a lack of empirical data on managing post-concussive symptoms in preschoolers during the recovery period.
NEUROPSYCHOLOGY REVIEW
(2022)
Review
Psychology, Multidisciplinary
Janeen Bower, Wendy L. Magee, Cathy Catroppa, Felicity Anne Baker
Summary: The study synthesized 46 studies investigating the neural processing of music in children aged 0-18 years. It was found that children process music more slowly compared to adults, with immature cortical areas impacting musical processing and function localization. Complex music processing in infants and young children continues to mature into late adolescence.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Clinical Neurology
Louise M. Crowe, Cathy Catroppa, Franz E. Babl, Celia Godfrey, Vicki Anderson
Summary: The study found that traumatic brain injury in early childhood is associated with lower IQ scores that persist for several years. Family environment plays a predictive role in IQ scores, rather than injury characteristics.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2021)
