Hyaluronic acid and neural stem cells: implications for biomaterial design

Enzyme-mediated hyaluronic acid–tyramine hydrogels for the propagation of human embryonic stem cells in 3D

(2015) Keming Xu et al.   Acta Biomaterialia

Cell encapsulation in a magnetically aligned collagen–GAG copolymer microenvironment

(2015) Tyler Novak et al.   Acta Biomaterialia

Dynamic stiffening of poly(ethylene glycol)-based hydrogels to direct valvular interstitial cell phenotype in a three-dimensional environment

(2015) Kelly M. Mabry et al.   BIOMATERIALS

Accelerated wound healing by injectable microporous gel scaffolds assembled from annealed building blocks

(2015) Donald R. Griffin et al.   NATURE MATERIALS

Dynamic phototuning of 3D hydrogel stiffness

(2015) Ryan S. Stowers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD44: molecular interactions, signaling and functions in the nervous system

(2015) Joanna Dzwonek et al.   Frontiers in Cellular Neuroscience

Static stretch affects neural stem cell differentiation in an extracellular matrix-dependent manner

(2015) Janahan Arulmoli et al.   Scientific Reports

Porous Hyaluronic Acid Hydrogels for Localized Nonviral DNA Delivery in a Diabetic Wound Healing Model

(2015) Talar Tokatlian et al.   Advanced Healthcare Materials

Delivery of iPS-NPCs to the Stroke Cavity within a Hyaluronic Acid Matrix Promotes the Differentiation of Transplanted Cells

(2014) Jonathan Lam et al.   ADVANCED FUNCTIONAL MATERIALS

Hydrogels: Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems (Adv. Mater. 6/2014)

(2014) Daniel D. McKinnon et al.   ADVANCED MATERIALS

Developmentally regulated collagen/integrin interactions confer adhesive properties to early postnatal neural stem cells

(2014) Tobias Bergström et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Interaction of Hyaluronan Binding Peptides with Glycosaminoglycans in Poly(ethylene glycol) Hydrogels

(2014) Justine J. Roberts et al.   BIOMACROMOLECULES

The role of SDF-1α–ECM crosstalk in determining neural stem cell fate

(2014) Caroline P. Addington et al.   BIOMATERIALS

Magnetically Aligned Supramolecular Hydrogels

(2014) Matthew Wallace et al.   CHEMISTRY-A EUROPEAN JOURNAL

Tissue integrity signals communicated by high-molecular weight hyaluronan and the resolution of inflammation

(2014) S. M. Ruppert et al.   IMMUNOLOGIC RESEARCH

Heparin Prevents Intracellular Hyaluronan Synthesis and Autophagy Responses in Hyperglycemic Dividing Mesangial Cells and Activates Synthesis of an Extensive Extracellular Monocyte-adhesive Hyaluronan Matrix after Completing Cell Division

(2014) Aimin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions

(2014) Hal X. Nguyen et al.   JOURNAL OF COMPARATIVE NEUROLOGY

RNA sequencing of microglia and monocyte-derived macrophages from mice with experimental autoimmune encephalomyelitis illustrates a changing phenotype with disease course

(2014) Nuruddeen D. Lewis et al.   JOURNAL OF NEUROIMMUNOLOGY

Engineering In Situ Cross-Linkable and Neurocompatible Hydrogels

(2014) Xiaowei Li et al.   JOURNAL OF NEUROTRAUMA

Advanced biomaterials for repairing the nervous system: what can hydrogels do for the brain?

(2014) Zin Z. Khaing et al.   Materials Today

Protective Properties of Neural Extracellular Matrix

(2014) Anne Suttkus et al.   MOLECULAR NEUROBIOLOGY

Hyaluronan-based extracellular matrix under conditions of homeostatic plasticity

(2014) J. C. Valenzuela et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Knock-Down of CD44 Regulates Endothelial Cell Differentiation via NFκB-Mediated Chemokine Production

(2014) Berit Olofsson et al.   PLoS One

Enhanced cognitive flexibility in reversal learning induced by removal of the extracellular matrix in auditory cortex

(2014) M. F. K. Happel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Injury to the Spinal Cord Niche Alters the Engraftment Dynamics of Human Neural Stem Cells

(2014) Christopher J. Sontag et al.   Stem Cell Reports

Chemical sintering generates uniform porous hyaluronic acid hydrogels

(2013) Cynthia Cam et al.   Acta Biomaterialia

Hyaluronan: A simple polysaccharide with diverse biological functions

(2013) Kevin T. Dicker et al.   Acta Biomaterialia

Synthesis of Photodegradable Macromers for Conjugation and Release of Bioactive Molecules

(2013) Donald R. Griffin et al.   BIOMACROMOLECULES

Repair of the injured spinal cord by transplantation of neural stem cells in a hyaluronan-based hydrogel

(2013) Andrea J. Mothe et al.   BIOMATERIALS

Dynamic tissue engineering scaffolds with stimuli-responsive macroporosity formation

(2013) Li-Hsin Han et al.   BIOMATERIALS

Porous chitosan-hyaluronic acid scaffolds as a mimic of glioblastoma microenvironment ECM

(2013) Stephen J. Florczyk et al.   BIOMATERIALS

The survival of engrafted neural stem cells within hyaluronic acid hydrogels

(2013) Yajie Liang et al.   BIOMATERIALS

Channel density and porosity of degradable bridging scaffolds on axon growth after spinal injury

(2013) Aline M. Thomas et al.   BIOMATERIALS

Augmentation of integrin-mediated mechanotransduction by hyaluronic acid

(2013) Anant Chopra et al.   BIOMATERIALS

Non-viral DNA delivery from porous hyaluronic acid hydrogels in mice

(2013) Talar Tokatlian et al.   BIOMATERIALS

Selective expression of hyaluronan and receptor for hyaluronan mediated motility (Rhamm) in the adult mouse subventricular zone and rostral migratory stream and in ischemic cortex

(2013) Charlotta Lindwall et al.   BRAIN RESEARCH

Hydrogels for lentiviral gene delivery

(2013) Stephanie K Seidlits et al.   Expert Opinion on Drug Delivery

Immobilized Heavy Chain-Hyaluronic Acid Polarizes Lipopolysaccharide-activated Macrophages toward M2 Phenotype

(2013) Hua He et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic acid-based hydrogel enhances neuronal survival in spinal cord slice cultures from postnatal mice

(2013) Nikos Schizas et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Hyaluronic Acid Click Hydrogels Emulate the Extracellular Matrix

(2013) Shawn C. Owen et al.   LANGMUIR

Mechanical Properties and Degradation of Chain and Step-Polymerized Photodegradable Hydrogels

(2013) Mark W. Tibbitt et al.   MACROMOLECULES

Perineuronal and perisynaptic extracellular matrix in the human spinal cord

(2013) C. Jäger et al.   NEUROSCIENCE

In Vivo Molecular Markers for Pro-inflammatory Cytokine M1 Stage and Resident Microglia in Trimethyltin-Induced Hippocampal Injury

(2013) C. A. McPherson et al.   NEUROTOXICITY RESEARCH

Dynamic Changes of CD44 Expression from Progenitors to Subpopulations of Astrocytes and Neurons in Developing Cerebellum

(2013) Masae Naruse et al.   PLoS One

Directing neural stem cell fate with biomaterial parameters for injured brain regeneration

(2013) Shenglian Yao et al.   Progress in Natural Science-Materials International

Hydrogel formulation determines cell fate of fetal and adult neural progenitor cells

(2013) Emily R. Aurand et al.   Stem Cell Research

Seizure-like activity in hyaluronidase-treated dissociated hippocampal cultures

(2013) Maria Vedunova et al.   Frontiers in Cellular Neuroscience

Digestion products of the PH20 hyaluronidase inhibit remyelination

(2012) Marnie Preston et al.   ANNALS OF NEUROLOGY

Design of Biomimetic Cell-Interactive Substrates Using Hyaluronic Acid Hydrogels with Tunable Mechanical Properties

(2012) Emilie Hachet et al.   BIOMACROMOLECULES

Hydrogel macroporosity and the prolongation of transgene expression and the enhancement of angiogenesis

(2012) Jaclyn A. Shepard et al.   BIOMATERIALS

The effects of intrathecal injection of a hyaluronan-based hydrogel on inflammation, scarring and neurobehavioural outcomes in a rat model of severe spinal cord injury associated with arachnoiditis

(2012) James W. Austin et al.   BIOMATERIALS

The effect of long-term release of Shh from implanted biodegradable microspheres on recovery from spinal cord injury in mice

(2012) Natalia Lowry et al.   BIOMATERIALS

Synergistic effects of SDF-1α chemokine and hyaluronic acid release from degradable hydrogels on directing bone marrow derived cell homing to the myocardium

(2012) Brendan P. Purcell et al.   BIOMATERIALS

Injectable hydrogels for central nervous system therapy

(2012) Malgosia M Pakulska et al.   Biomedical Materials

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells

(2012) Jian Chen et al.   CELL

The perineuronal net and the control of CNS plasticity

(2012) Difei Wang et al.   CELL AND TISSUE RESEARCH

Gender-Dependent Levels of Hyaluronic Acid in Cerebrospinal Fluid of Patients with Neurodegenerative Dementia

(2012) Henrietta M. Nielsen et al.   Current Alzheimer Research

Engineering an in situ crosslinkable hydrogel for enhanced remyelination

(2012) Xiaowei Li et al.   FASEB JOURNAL

Chemotactic recruitment of adult neural progenitor cells into multifunctional hydrogels providing sustained SDF-1α release and compatible structural support

(2012) Teck Chuan Lim et al.   FASEB JOURNAL

CD44 is required for the migration of transplanted oligodendrocyte progenitor cells to focal inflammatory demyelinating lesions in the spinal cord

(2012) Jing-Hua Piao et al.   GLIA

The High and Low Molecular Weight Forms of Hyaluronan Have Distinct Effects on CD44 Clustering

(2012) Cuixia Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High molecular weight hyaluronan reduces lipopolysaccharide mediated microglial activation

(2012) James W. Austin et al.   JOURNAL OF NEUROCHEMISTRY

The perineuronal net component of the extracellular matrix in plasticity and epilepsy

(2012) Paulette A. McRae et al.   NEUROCHEMISTRY INTERNATIONAL

Hyaluronan tetrasaccharide in the cerebrospinal fluid is associated with self-repair of rats after chronic spinal cord compression

(2012) J. Wang et al.   NEUROSCIENCE

CD44 expression in astrocytes and microglia is associated with ALS progression in a mouse model

(2012) Tomohiro Matsumoto et al.   NEUROSCIENCE LETTERS

Advances in natural biomaterials for nerve tissue repair

(2012) Zin Z. Khaing et al.   NEUROSCIENCE LETTERS

3D Differentiation of Neural Stem Cells in Macroporous Photopolymerizable Hydrogel Scaffolds

(2012) Hang Li et al.   PLoS One

The role of hyaluronan in wound healing

(2012) Joseph S Frenkel   International Wound Journal

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

White matter lesions defined by diffusion tensor imaging in older adults

(2011) Stephen A. Back et al.   ANNALS OF NEUROLOGY

Single-Cell Redox Imaging Demonstrates a Distinctive Response of Dopaminergic Neurons to Oxidative Insults

(2011) Maxx P. Horowitz et al.   ANTIOXIDANTS & REDOX SIGNALING

Diels−Alder Click Cross-Linked Hyaluronic Acid Hydrogels for Tissue Engineering

(2011) Chelsea M. Nimmo et al.   BIOMACROMOLECULES

Elucidating the mechanobiology of malignant brain tumors using a brain matrix-mimetic hyaluronic acid hydrogel platform

(2011) Badriprasad Ananthanarayanan et al.   BIOMATERIALS

Multifunctional, multichannel bridges that deliver neurotrophin encoding lentivirus for regeneration following spinal cord injury

(2011) Hannah M. Tuinstra et al.   BIOMATERIALS

Neuroprotection: The Emerging Concept of Restorative Neural Stem Cell Biology for the Treatment of Neurodegenerative Diseases

(2011) Fiorella Piemonte et al.   Current Neuropharmacology

Glia unglued: How signals from the extracellular matrix regulate the development of myelinating glia

(2011) Holly Colognato et al.   Developmental Neurobiology

Extracellular matrix and perineuronal nets in CNS repair

(2011) Jessica C.F. Kwok et al.   Developmental Neurobiology

Cell-based transplantation strategies to promote plasticity following spinal cord injury

(2011) Crystal A. Ruff et al.   EXPERIMENTAL NEUROLOGY

Role of Receptor for Hyaluronic Acid-mediated Motility (RHAMM) in Low Molecular Weight Hyaluronan (LMWHA)-mediated Fibrosarcoma Cell Adhesion

(2011) Katerina Kouvidi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic acid and fibrin hydrogels with concentrated DNA/PEI polyplexes for local gene delivery

(2011) Yuguo Lei et al.   JOURNAL OF CONTROLLED RELEASE

High molecular weight hyaluronic acid limits astrocyte activation and scar formation after spinal cord injury

(2011) Zin Z Khaing et al.   Journal of Neural Engineering

Tunable Growth Factor Delivery from Injectable Hydrogels for Tissue Engineering

(2011) Katarina Vulic et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization of a Hierarchical Network of Hyaluronic Acid/Gelatin Composite for use as a Smart Injectable Biomaterial

(2011) Hossein K. Heris et al.   MACROMOLECULAR BIOSCIENCE

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels

(2011) Ryan G. Wylie et al.   NATURE MATERIALS

Astrocytes in aged nonhuman primate brain gray matter synthesize excess hyaluronan

(2011) Robert Cargill et al.   NEUROBIOLOGY OF AGING

Combination of Hyaluronic Acid Hydrogel Scaffold and PLGA Microspheres for Supporting Survival of Neural Stem Cells

(2011) Ying Wang et al.   PHARMACEUTICAL RESEARCH

Rho GTPases Mediate the Mechanosensitive Lineage Commitment of Neural Stem Cells

(2011) Albert J. Keung et al.   STEM CELLS

Hyaluronan scaffolds: A balance between backbone functionalization and bioactivity

(2010) Doris Eng et al.   Acta Biomaterialia

Crystal templating dendritic pore networks and fibrillar microstructure into hydrogels

(2010) Scott A. Zawko et al.   Acta Biomaterialia

Cells of the oligodendroglial lineage, myelination, and remyelination

(2010) Veronique E. Miron et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The effects of hyaluronic acid hydrogels with tunable mechanical properties on neural progenitor cell differentiation

(2010) Stephanie K. Seidlits et al.   BIOMATERIALS

Expression of hyaluronan and the hyaluronan-binding proteoglycans neurocan, aggrecan, and versican by neural stem cells and neural cells derived from embryonic stem cells

(2010) Mary Abaskharoun et al.   BRAIN RESEARCH

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

Peptide-Functionalized Click Hydrogels with Independently Tunable Mechanics and Chemical Functionality for 3D Cell Culture

(2010) Cole A. DeForest et al.   CHEMISTRY OF MATERIALS

Interactions between oligodendrocyte precursors control the onset of CNS myelination

(2010) Yan Yang et al.   DEVELOPMENTAL BIOLOGY

The spinal cord ependymal region: A stem cell niche in the caudal central nervous system

(2010) Jean et al.   Frontiers in Bioscience-Landmark

Two-photon lithography in the future of cell-based therapeutics and regenerative medicine: a review of techniques for hydrogel patterning and controlled release

(2010) Andrea M Kasko et al.   Future Medicinal Chemistry

Hyaluronic acid hydrogel modified with nogo-66 receptor antibody and poly-L-lysine to promote axon regrowth after spinal cord injury

(2010) Yue-Teng Wei et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Photocleavable side groups to spatially alter hydrogel properties and cellular interactions

(2010) Vyas V. Ramanan et al.   JOURNAL OF MATERIALS CHEMISTRY

TLR2 activation inhibits embryonic neural progenitor cell proliferation

(2010) Eitan Okun et al.   JOURNAL OF NEUROCHEMISTRY

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

(2010) Alexander Dityatev et al.   NATURE REVIEWS NEUROSCIENCE

Perineuronal net formation and structure in aggrecan knockout mice

(2010) K.A. Giamanco et al.   NEUROSCIENCE

Hyaluronan oligosaccharides promote functional recovery after spinal cord injury in rats

(2010) Norimitsu Wakao et al.   NEUROSCIENCE LETTERS

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

(2010) J. A. Sloane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-dimensional photolithographic patterning of multiple bioactive ligands in poly(ethylene glycol) hydrogels

(2010) Joseph C. Hoffmann et al.   Soft Matter

Patterning hydrogels in three dimensions towards controlling cellular interactions

(2010) Sudhir Khetan et al.   Soft Matter

Role of hyaluronan in glioma invasion

(2010) Jong Bae Park et al.   Cell Adhesion & Migration

High-Resolution Patterning of Hydrogels in Three Dimensions using Direct-Write Photofabrication for Cell Guidance

(2009) Stephanie K. Seidlits et al.   ADVANCED FUNCTIONAL MATERIALS

The influence of hydrogel modulus on the proliferation and differentiation of encapsulated neural stem cells

(2009) Akhilesh Banerjee et al.   BIOMATERIALS

The promotion of neuronal maturation on soft substrates

(2009) Ana I. Teixeira et al.   BIOMATERIALS

The effect of substrate stiffness on adult neural stem cell behavior

(2009) Nic D. Leipzig et al.   BIOMATERIALS

Response of Ependymal Progenitors to Spinal Cord Injury or Enhanced Physical Activity in Adult Rat

(2009) Dasa Cizkova et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Viability and differentiation of neural precursors on hyaluronic acid hydrogel scaffold

(2009) Linjie Pan et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Up-regulation of oligodendrocyte precursor cell αV integrin and its extracellular ligands during central nervous system remyelination

(2009) Chao Zhao et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Hyaluronic acid inhibits the glial scar formation after brain damage with tissue loss in rats

(2009) Chien-Min Lin et al.   SURGICAL NEUROLOGY

Microbubbles in ultrasound-triggered drug and gene delivery

(2008) Sophie Hernot et al.   ADVANCED DRUG DELIVERY REVIEWS

Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury

(2008) Kristen N. Segovia et al.   ANNALS OF NEUROLOGY

In vivo real-time bioimaging of hyaluronic acid derivatives using quantum dots

(2008) Jiseok Kim et al.   BIOPOLYMERS

Brain Extracellular Matrix in Neurodegeneration

(2008) Dafna Bonneh-Barkay et al.   BRAIN PATHOLOGY

Targeting Hyaluronan Interactions in Malignant Gliomas and Their Drug-Resistant Multipotent Progenitors

(2008) A. G. Gilg et al.   CLINICAL CANCER RESEARCH

Hyaluronan, CD44 and Emmprin: Partners in cancer cell chemoresistance

(2008) Bryan P. Toole et al.   DRUG RESISTANCE UPDATES

Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin-R in the rat spinal cord

(2008) Clare M. Galtrey et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

HyaluronanCD44 pathway regulates orientation of mitotic spindle in normal epithelial cells

(2008) Takeshi Fujiwara et al.   GENES TO CELLS

Extracellular matrix of the central nervous system: from neglect to challenge

(2008) Dieter R. Zimmermann et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Cell-surface and mitotic-spindle RHAMM: moonlighting or dual oncogenic functions?

(2008) C. A. Maxwell et al.   JOURNAL OF CELL SCIENCE

Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation

(2008) Steven M. Pollard et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Hyaluronan: A constitutive regulator of chemoresistance and malignancy in cancer cells

(2008) Bryan P. Toole et al.   SEMINARS IN CANCER BIOLOGY

Molecular Mechanism of Systemic Delivery of Neural Precursor Cells to the Brain: Assembly of Brain Endothelial Apical Cups and Control of Transmigration by CD44

(2008) Christine Rampon et al.   STEM CELLS

Spinal Cord Injury Reveals Multilineage Differentiation of Ependymal Cells

(2008) Konstantinos Meletis et al.   PLOS BIOLOGY

Hyaluronan accumulates around differentiating neurons in spinal cord of chicken embryos

(2007) Zoltán Mészár et al.   BRAIN RESEARCH BULLETIN

Aggrecan-based extracellular matrix is an integral part of the human basal ganglia circuit

(2007) G. Brückner et al.   NEUROSCIENCE

Brain micro-ecologies: neural stem cell niches in the adult mammalian brain

(2007) P. A Riquelme et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A ‘GAG’ reflex prevents repair of the damaged CNS

(2007) Larry S. Sherman et al.   TRENDS IN NEUROSCIENCES