Article
Computer Science, Artificial Intelligence
Martin Papco, Iosu Rodriguez-Martinez, Javier Fumanal-Idocin, Abdulrahman H. Altalhi, Humberto Bustince
Summary: This paper proposes an extension of the deviation-based aggregation function tailored to aggregate multidimensional data, aiming to obtain favorable results in areas with strict temporal constraints such as image processing, deep learning, and decision making.
INFORMATION FUSION
(2021)
Article
Computer Science, Artificial Intelligence
Dojin Choi, Hyeonbyeong Lee, Jongtae Lim, Kyoungsoo Bok, Jaesoo Yoo
Summary: In this paper, a novel and effective continuous subgraph matching scheme leveraging indexing and distributed processing is proposed for real-time graph stream environments. The scheme manages decomposed subqueries as an index based on the degree of nodes and introduces a cost model to optimize query allocation. The implemented scheme in Storm is evaluated to demonstrate its superiority.
KNOWLEDGE-BASED SYSTEMS
(2023)
Article
Health Care Sciences & Services
Joseph Ross Mitchell, Phillip Szepietowski, Rachel Howard, Phillip Reisman, Jennie D. Jones, Patricia Lewis, Brooke L. Fridley, Dana E. Rollison
Summary: This study developed a BERT-based NLP system to automatically extract detailed tumor site and histology information from oncological pathology reports. The system outperformed existing algorithms in predicting ICD-O-3 codes, which could improve cancer treatment outcomes.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Computer Science, Artificial Intelligence
Ruiyuan Li, Huajun He, Rubin Wang, Sijie Ruan, Tianfu He, Jie Bao, Junbo Zhang, Liang Hong, Yu Zheng
Summary: With the development of positioning technology, a large amount of trajectory data has been generated, which is valuable for urban applications. However, managing such data is challenging due to its spatio-temporal dynamics and high-volume properties. Existing trajectory data management frameworks have efficiency and scalability issues, and limited support for query types. This paper introduces TrajMesa, a holistic distributed NoSQL trajectory query engine based on the open-source indexing toolkit GeoMesa, which efficiently manages a large number of trajectories and supports various query types.
IEEE TRANSACTIONS ON KNOWLEDGE AND DATA ENGINEERING
(2023)
Article
Nuclear Science & Technology
Yu Gu, Mengqi Fan, Yuanzhe Zhao, Xiaodan Zhang
Summary: The experimental system architecture is being redesigned to meet the needs of future long pulse experiments, focusing on upgrading data protocols and processing mechanisms for improved real-time feedback and compatibility. Adaptive strategies and optimization technologies are used to enhance data processing efficiency and storage management.
FUSION ENGINEERING AND DESIGN
(2021)
Article
Energy & Fuels
Daniel Mikkelson, J. Michael Doster
Summary: This paper presents two CTES models, namely the single-pipe network design and the dual-pipe network design, to analyze their potential applications in constant steam production. The results indicate that the single-pipe network design is suitable for batch energy applications, while the dual-pipe network design is appropriate for continuous energy applications.
JOURNAL OF ENERGY STORAGE
(2022)
Article
Chemistry, Multidisciplinary
Ciaran J. Rogers, Deepak Asthana, Adam Brookfield, Alessandro Chiesa, Grigore A. Timco, David Collison, Louise S. Natrajan, Stefano Carretta, Richard E. P. Winpenny, Alice M. Bowen
Summary: In this study, we report the synthesis of a molecular multi-qubit model system with three weakly interacting spin 1/2 centers. By characterizing and separately addressing the individual spin qubits, we determine the strength of the inter-qubit dipolar interaction. Our findings suggest that this system could be utilized for EPR-based quantum information processing algorithms.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Automation & Control Systems
Jin Guo, Xuebin Wang, Wenchao Xue, Yanlong Zhao
Summary: This article addresses the defense problem against data tampering attack in cyber-physical systems. It shows how attackers aim to achieve maximum hit effect with minimal attack energy. The proposed compensation-oriented defense approach and corresponding identification algorithm prove strong consistency and establish an optimal defense scheme.
IEEE TRANSACTIONS ON AUTOMATIC CONTROL
(2021)
Article
Computer Science, Information Systems
Michael D. Collins, Joseph F. Lingevitch
Summary: The MVB processor is a useful tool for determining the locations of multiple acoustic sources in the ocean, based on the eigenvectors of the covariance matrix. It allows for determining energy partitioning without the need for computing replica fields, making it advantageous for matched-field processing computations. Examples are presented to show the capabilities and limitations of the approach.
Article
Environmental Sciences
Hushan Lv, Yongrui Li, Yizhuang Xie, Tingting Qiao
Summary: This study introduces a three-dimensional cross-mapping approach and an on-chip data transfer approach based on a superscalar pipeline to improve the data storage and transfer efficiency of SAR imaging systems. The hardware architecture designed and the experimental results obtained demonstrate that the proposed methods can significantly increase the storage access bandwidth and enhance the data transfer efficiency, making them suitable for real-time processing systems in spaceborne SAR.
Review
Chemistry, Analytical
Puneet Mishra, Jean-Michel Roger, Delphine Jouan-Rimbaud-Bouveresse, Alessandra Biancolillo, Federico Marini, Alison Nordon, Douglas N. Rutledge
Summary: This review provides a brief overview of popular multi-block data analysis methods, including their concepts, applications, advantages and disadvantages, as well as software resources, emphasizing their importance in the field of chemometrics.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Jihyun Kim, Myeongjin Jung, Dong Un Lim, Dongjoon Rhee, Sung Hyeon Jung, Hyung Koun Cho, Han-Ki Kim, Jeong Ho Cho, Joohoon Kang
Summary: Multi-valued logic gates are demonstrated on solution-processed molybdenum disulfide (MoS2) thin films by locally increasing the work function of MoS2 through a chemical doping process. Current levels and turn-on voltages for each state can be tuned by modulating the device geometries, eventually leading to the demonstration of various ternary logic gates.
Article
Engineering, Electrical & Electronic
Stefan K. Weber, Giovanna Lehmann Miotto, Joao Almeida, Pascal Herve Blanc, Antonio Dias, Giulio Malaguti, Hanna E. Manninen, Joschka Pfeifer, Sylvain Ravat, Antti Onnela, Serge Mathot, Jasper Kirkby, Antonio Tome, Antonio Amorim
Summary: The CLOUD experiment at CERN investigates aerosol particles under atmospheric conditions, utilizing a clean chamber and advanced instruments. The DAQ system integrates data from these instruments into a single database, ensuring flexibility and fast response.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2021)
Article
Computer Science, Artificial Intelligence
Xuefei Wu, Jiahui Huang
Summary: This study presents an integrated service management system for rural tourist information based on a cloud platform. It addresses the challenges of high platform concurrency, data storage and management difficulties, and data function sharing troubles. The platform design considers three levels - data, process, and architecture. By utilizing Netty data transmission technology, hybrid data storage technology, and the Web Foundation, the Hadoop data storage system enables the collection, storage, administration, and exchange of large amounts of heterogeneous data from various sources. The results demonstrate the system's low response time, meeting the actual needs of CPU consumption time and average utilization rate. It effectively resolves issues in current rural tourism platform applications, including data collection difficulties, low reuse rate, low sharing rate, lack of timely updates, and severe island phenomena.
PEERJ COMPUTER SCIENCE
(2023)
Article
Engineering, Electrical & Electronic
Yong Wan, Zhonghui Ji
Summary: This paper proposes a generalized continuous random process modeling framework to impose any desired probability distribution, autocorrelation, and power spectral density on measured data of power system uncertainty. The proposed stochastic differential equation (SDE) model, together with a quadratic output equation, is used and an algorithm for determining appropriate parameters is presented. Comparative simulations using actual time series data show the effectiveness of the derived random modeling scheme for wind speed, solar radiation, PJM dynamic regulation, and wind power. The proposed SDE model can be easily integrated into various electrical component models for reliable operation, stability assessment, and control of renewable power systems.
IEEE TRANSACTIONS ON POWER SYSTEMS
(2023)
Article
Chemistry, Multidisciplinary
Anna C. Closs, Maximilian Bechtel, Oliver Trapp
Summary: Evolutionary biological processes lead to changes in heritable traits, where the responsible genetic information in DNA is altered, selected, and inherited through the mutation of the base sequence. Evolutionary changes at the molecular level of small organic molecules are unknown but represent an important prerequisite for the emergence of life, where catalysts can exhibit different selectivity during formation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biology
Klaus Paschek, Kai Kohler, Ben K. D. Pearce, Kevin Lange, Thomas K. Henning, Oliver Trapp, Ralph E. Pudritz, Dmitry A. Semenov
Summary: The origin of life on early Earth might be closely related to the formation of ribose in carbonaceous chondrites, which is a crucial component of the RNA world. Through laboratory experiments and theoretical calculations, researchers found that the aqueous formose reaction could produce a significant amount of ribose in carbonaceous chondrites. This discovery sheds light on the possible synthesis of life-building blocks on Earth.
Article
Chemistry, Physical
Sabrina Kraeh, Iris Kachel, Oliver Trapp
Summary: Palladium-catalyzed cross-coupling reactions are efficient methods for organic synthesis, but heteroatom-containing compounds often complicate these reactions. This study introduces a highly active phosphine ligand that enables excellent yields in C-N coupling reactions at ambient temperature. The unique structure of the ligand, incorporating a silicon atom and a cyclohexane moiety, results in electron-rich properties. This ligand facilitates a broad range of coupling reactions under mild conditions in palladium catalysis.
Article
Chemistry, Organic
Jan-Michael Menke, Oliver Trapp
Summary: For the preparation of chiral drugs, the combination of stereochemically stable and flexible catalysts with chiral auxiliaries is crucial. In this study, a successful approach to the spontaneous deracemization of tropos ligands for asymmetric catalysis was demonstrated.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Editorial Material
Biochemistry & Molecular Biology
Oliver Trapp
Article
Biology
Laura Huber, Oliver Trapp
Summary: This study developed a method to investigate the reaction kinetics of single molecules in order to understand chiral symmetry breaking at the molecular level. The results showed that interlocking processes can amplify the occurrence of symmetry breaking, providing a promising direction for experimental implementation and identification of these processes.
ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES
(2022)
Article
Multidisciplinary Sciences
Guiyang Yao, Simone Kosol, Marius T. Wenz, Elisabeth Irran, Bettina G. Keller, Oliver Trapp, Roderich D. Suessmuth
Summary: This article reports the use of the term "ansamer" to describe the isomers of the bicyclic octapeptide alpha-Amanitin. The researchers synthesized analogs of alpha-Amanitin and analyzed their isomers, proposing and describing the term "ansamer" for these isomers.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Constanze Sydow, Christiane Seiband, Alexander F. Siegle, Oliver Trapp
Summary: Organophosphates play important roles in living organisms, but their prebiotic origins are unknown. In this study, the authors demonstrate the efficient formation of organophosphates through a phosphorylation reaction in liquid sulfur dioxide at room temperature. This reaction could have occurred in volcanic environments on Early Earth, and it also has potential applications in synthetic chemistry.
COMMUNICATIONS CHEMISTRY
(2022)
Review
Chemistry, Multidisciplinary
Lena C. Mayer, Simone Heitsch, Oliver Trapp
Summary: Asymmetric synthesis plays a crucial role in preparing enantiomerically pure compounds and controlling individual stereocenters in complex compound synthesis. It relies on the use of enantiopure catalysts and configurationally flexible ligands or organocatalysts. The design of smart catalyst systems that combine supramolecular recognition, stereoconvergent alignment, and catalysis has been successful in enhancing enantioselectivity in asymmetric catalysis.
ACCOUNTS OF CHEMICAL RESEARCH
(2022)
Editorial Material
Chemistry, Medicinal
Simona Collina, Simone Lucarini, Jordi Benet-Buchholz, Simona Collina, Oliver Trapp, Gennaro Pescitelli, Nina Berova
Article
Chemistry, Medicinal
Simone Heitsch, Lena Carina Mayer, Yanis Luca Pignot, Oliver Trapp
Summary: Soai's asymmetric autocatalysis is a remarkable example of symmetry breaking and enantioselective amplification in the alkylation of pyrimidine-5-carbaldehydes. Zinc hemiacetalate complexes formed from the aldehydes and the chiral product alcohol were identified as highly active catalysts in this transformation. By studying the synthesis of coumarin homolog biaryl systems, it was found that they can form hemiacetals through intramolecular cyclization, with the ability to enable or disable this process depending on the tropos or atropos configuration.
Article
Chemistry, Multidisciplinary
Constanze Sydow, Fabian Sauer, Alexander F. Siegle, Oliver Trapp
Summary: Peptides play essential roles in the structure and catalytic functions of living organisms. The formation of peptides faces thermodynamic and kinetic barriers. Recent studies have explored various formation scenarios during the origin of life, including iron(III)-catalyzed condensations. However, iron(III)-catalysts often have low catalytic activity at elevated temperatures. This study demonstrates that reduced iron activated by acetic acid efficiently mediates peptide formation, providing a potential pathway for the formation of the first peptides in anoxic environments.
Review
Chemistry, Multidisciplinary
Lena C. Mayer, Simone Heitsch, Oliver Trapp
Summary: Asymmetric synthesis is a crucial technique for the preparation of chiral compounds and the control of stereocenters in complex syntheses. Configurationally flexible ligands and catalysts can be enriched through dynamic processes, leading to improved enantioselectivity in asymmetric catalysis. This strategy has significant implications for the development of new catalytic applications and understanding of chirality amplification and homochirality in biological systems.
ACCOUNTS OF CHEMICAL RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Maximilian Bechtel, Eva Hummer, Oliver Trapp
Summary: Nucleotides play a vital role in organisms, but there has been no effective selective pathway for their formation. In this study, we have discovered a selective nucleotide synthesis reaction pathway under extremely mild prebiotic conditions for all major bases. This finding opens up new avenues for studying the origins of life.
Article
Chemistry, Multidisciplinary
Mario Grosch, Martin T. Stiebritz, Robert Bolney, Mario Winkler, Eric Jueckstock, Hannah Busch, Sophia Peters, Alexander F. Siegle, Joris van Slageren, Markus Ribbe, Yilin Hu, Oliver Trapp, Christian Robl, Wolfgang Weigand
Summary: This study provides evidence for mackinawite-supported reduction of KCN and proposes a reaction mechanism. The findings open new avenues for investigating other substrates for mackinawite-supported reactions and shed light on the relevance of this type of reaction to the origin of life on Earth.
Article
Chemistry, Multidisciplinary
Alexander M. Prophet, Kritanjan Polley, Gary J. Van Berkel, David T. Limmer, Kevin R. Wilson
Summary: The oxidation kinetics of iodide by ozone at the air-water interface is studied in single microdroplets. Molecular simulations and kinetic modeling are used to understand the underlying multiphase mechanism.
Article
Chemistry, Multidisciplinary
Rong Zhang, Jiajing Lan, Fei Wang, Shumei Chen, Jian Zhang
Summary: By utilizing 1,1'-ferrocene dicarboxylic acid as a chelating and surface protection ligand, we have synthesized multi-nuclear indium oxide clusters with varying nuclear sizes, including heptanuclear and thirteen-nuclear clusters. These clusters possess labile coordination sites, allowing for structural modification and self-assembly, resulting in the formation of various cluster structures.
Article
Chemistry, Multidisciplinary
Hui Wang, Hui Liu, Mingsen Wang, Jiaheng Hou, Yongjun Li, Yuancheng Wang, Yingjie Zhao
Summary: Two supramolecular complexes were prepared using CBs and M1, and their single-crystal structures were analyzed by SCXRD. The unexpected 1:2 self-assembly structure between M1 and CB[8] was discovered for the first time. These complexes exhibit unique photophysical properties and provide valuable information about the structure and photophysical properties of supramolecular complexes.
Article
Chemistry, Multidisciplinary
Chang-Hee Lee, Sookil Park, Sanggil Kim, Ji Young Hyun, Hyun Soo Lee, Injae Shin
Summary: The epidermal growth factor receptor (EGFR) is a cell-surface glycoprotein involved in cell proliferation and tumor development. This study used a fluorescently labeled EGFR to investigate its time-dependent endocytosis in live cells and found that appended glycans affect EGFR internalization. Additionally, the study detected sialic acid residues attached to EGFR on the live cell surface using FRET-based imaging. This research provides valuable insights into the cellular functions of EGFR.
Article
Chemistry, Multidisciplinary
Subhankar Sahu, Lokesh Kumar, Sumita Das, Dipti Gupta, Ruchi Anand
Summary: This study proposes a strategy that combines organic electronics with biosensor scaffolds to create a compact device for monitoring environmental aromatic pollution. By coupling biosensing protein MopR with an organic electrochemical transistor (OECT), a sensor module capable of efficient detection of phenol was designed. Exclusive phenol detection with minimal loss of sensitivity could be achieved in complex pollutant mixtures and real environmental samples.
Review
Chemistry, Multidisciplinary
Changseok Lee, Hyung-Joon Kang, Sungwoo Hong
Summary: The formation of C-N bonds through hydroamination reactions catalyzed by nickel hydrides has been a topic of recent interest. This approach offers a way to efficiently transform a variety of alkene and alkyne substrates into compounds enriched with C-N bonds. The review provides a concise overview of the underlying reaction mechanisms and aims to stimulate further progress in NiH-catalytic techniques and catalyst design.
Article
Chemistry, Multidisciplinary
Yueci Wu, Lu-Lu Sun, Hai-Hao Han, Xiao-Peng He, Weiguo Cao, Tony D. James
Summary: Drug-induced liver injury (DILI) is a common cause of acute liver failure in the USA and Europe, but most cases can be recovered or prevented by discontinuing the offending drug. Recent research has found that peroxynitrite (ONOO-) can be used as a potential indicator for early diagnosis of DILI, and there is an urgent need to establish a method to detect and track peroxynitrite in DILI cases. In this study, a FRET-based nano fluorescent probe CD-N-I was developed, which showed high selectivity and sensitivity in detecting peroxynitrite. The probe successfully detected exogenous peroxynitrite in live cells and endogenous peroxynitrite in APAP-induced liver injury of HepG2 cells.
Article
Chemistry, Multidisciplinary
Dmitry L. Lipilin, Mikhail O. Zubkov, Mikhail D. Kosobokov, Alexander D. Dilman
Summary: This article describes a direct photocatalytic method for the thiolation of unprotected acids, which was previously challenging. By using a thionocarbonate reagent with an N-O bond, the efficient conversion of carboxylic acids to thiols is achieved.
Article
Chemistry, Multidisciplinary
Jason Malenfant, Lucille Kuster, Yohann Gagne, Kouassi Signo, Maxime Denis, Sylvain Canesi, Mathieu Frenette
Summary: Raman microscopy can reveal compound-specific vibrational fingerprints without sample preparation. The combination of efficient theoretical calculations and a user-friendly software can accurately predict peak positions and provide match scores to assist with structure determination.
Article
Chemistry, Multidisciplinary
Jayoh A. Hernandez, Paul S. Micus, Sean Alec Lois Sunga, Luca Mazzei, Stefano Ciurli, Gabriele Meloni
Summary: Essential trace metals play crucial roles in the survival and virulence of bacterial pathogens. Helicobacter pylori requires nickel for colonization and persistence in the stomach, and NixA is an essential nickel transporter in this process. This study characterizes the selectivity and electrogenic nature of NixA-mediated nickel transport.
Article
Chemistry, Multidisciplinary
Tarali Devi, Kuheli Dutta, Jennifer Deutscher, Stefan Mebs, Uwe Kuhlmann, Michael Haumann, Beatrice Cula, Holger Dau, Peter Hildebrandt, Kallol Ray
Summary: This study emphasizes the importance of subtle electronic changes and secondary interactions in the stability of biologically relevant metal-dioxygen intermediates. It also shows that the role of the chloride ligand in stabilizing the Fe-III-(OOBu)-Bu-t moiety can extend to other anions, including the thiolate ligand.
Article
Chemistry, Multidisciplinary
Jacqueline R. Santhouse, Jeremy M. G. Leung, Lillian T. Chong, W. Seth Horne
Summary: By studying the folding kinetics and mechanism of the BdpA sequence, researchers found that altering the backbone connectivity can affect protein folding. This suggests that protein mimetic chains have a significant degree of plasticity in transitioning between unfolded and folded states.
Article
Chemistry, Multidisciplinary
Divanshu Gupta, Ralf Einholz, Holger F. Bettinger
Summary: This study presents the first direct spectroscopic evidence of a cyclic seven-membered iminoborane. Compared to linear amino-iminoboranes, this cyclic iminoborane exhibits weakened bond strength and lower Lewis acidity value. The study suggests that the reduced ring strain of cyclic iminoborane prevents nitrogen fixation but allows facile (2 + 2) cycloaddition reaction with C2H4.
Article
Chemistry, Multidisciplinary
Renny Mathew, Aniruddha Mazumder, Praveen Kumar, Julie Matula, Sharmarke Mohamed, Petr Brazda, Mahesh Hariharan, Brijith Thomas
Summary: This study reveals the packing arrangement of partially disordered nitro-perylenediimide (NO2-PDI) using a synergistic approach that combines 3D ED, ssNMR, and DFT techniques. By overcoming these challenges, this methodology opens up new avenues for material characterization, driving exciting advancements in the field.
